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Items: 1 to 20 of 99

1.

Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function.

Brownlie RJ, Miosge LA, Vassilakos D, Svensson LM, Cope A, Zamoyska R.

Sci Signal. 2012 Nov 27;5(252):ra87. doi: 10.1126/scisignal.2003365.

PMID:
23193160
2.

Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis.

Salmond RJ, Brownlie RJ, Zamoyska R.

Cell Cycle. 2015;14(5):705-11. doi: 10.1080/15384101.2015.1007018.

3.

The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity.

Gianchecchi E, Palombi M, Fierabracci A.

Autoimmun Rev. 2013 May;12(7):717-25. doi: 10.1016/j.autrev.2012.12.003. Epub 2012 Dec 20. Review.

PMID:
23261816
4.

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

Wu DJ, Zhou W, Enouz S, Orrú V, Stanford SM, Maine CJ, Rapini N, Sawatzke K, Engel I, Fiorillo E, Sherman LA, Kronenberg M, Zehn D, Peterson E, Bottini N.

PLoS One. 2014 Feb 3;9(2):e86677. doi: 10.1371/journal.pone.0086677. eCollection 2014 Feb 3.

5.

Different modulation of Ptpn22 in effector and regulatory T cells leads to attenuation of autoimmune diabetes in transgenic nonobese diabetic mice.

Yeh LT, Miaw SC, Lin MH, Chou FC, Shieh SJ, Chuang YP, Lin SH, Chang DM, Sytwu HK.

J Immunol. 2013 Jul 15;191(2):594-607. doi: 10.4049/jimmunol.1203380. Epub 2013 Jun 10.

6.

Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.

Fousteri G, Jofra T, Di Fonte R, Gagliani N, Morsiani C, Stabilini A, Battaglia M.

Diabetologia. 2015 Jun;58(6):1319-28. doi: 10.1007/s00125-015-3540-9. Epub 2015 Mar 7.

PMID:
25748328
7.

Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.

Bottini N, Peterson EJ.

Annu Rev Immunol. 2014;32:83-119. doi: 10.1146/annurev-immunol-032713-120249. Epub 2013 Dec 18. Review.

PMID:
24364806
8.

PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.

Fousteri G, Jofra T, Di Fonte R, Kuka M, Iannacone M, Battaglia M.

Clin Immunol. 2015 Feb;156(2):98-108. doi: 10.1016/j.clim.2014.12.002. Epub 2014 Dec 13.

PMID:
25513733
9.

The role of PTPN22 in autoimmunity: learning from mice.

Zheng J, Petersen F, Yu X.

Autoimmun Rev. 2014 Mar;13(3):266-71. doi: 10.1016/j.autrev.2013.10.011. Epub 2013 Nov 1. Review.

PMID:
24189282
10.

The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization.

Fousteri G, Jofra T, Debernardis I, Stanford SM, Laurenzi A, Bottini N, Battaglia M.

Clin Exp Immunol. 2014 Oct;178(1):178-89. doi: 10.1111/cei.12393.

11.

Ptpn22 Modifies Regulatory T Cell Homeostasis via GITR Upregulation.

Nowakowska DJ, Kissler S.

J Immunol. 2016 Mar 1;196(5):2145-52. doi: 10.4049/jimmunol.1501877. Epub 2016 Jan 25.

12.

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.

Menard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, Meffre E.

J Clin Invest. 2011 Sep;121(9):3635-44. doi: 10.1172/JCI45790. Epub 2011 Aug 1.

13.

PTPN22 alters the development of regulatory T cells in the thymus.

Maine CJ, Hamilton-Williams EE, Cheung J, Stanford SM, Bottini N, Wicker LS, Sherman LA.

J Immunol. 2012 Jun 1;188(11):5267-75. doi: 10.4049/jimmunol.1200150. Epub 2012 Apr 25.

14.

Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity.

Burn GL, Cornish GH, Potrzebowska K, Samuelsson M, Griffié J, Minoughan S, Yates M, Ashdown G, Pernodet N, Morrison VL, Sanchez-Blanco C, Purvis H, Clarke F, Brownlie RJ, Vyse TJ, Zamoyska R, Owen DM, Svensson LM, Cope AP.

Sci Signal. 2016 Oct 4;9(448):ra99.

PMID:
27703032
15.

The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.

Salmond RJ, Brownlie RJ, Morrison VL, Zamoyska R.

Nat Immunol. 2014 Sep;15(9):875-83. doi: 10.1038/ni.2958. Epub 2014 Aug 10.

16.

Protein tyrosine phosphatase PTPN22 in human autoimmunity.

Vang T, Miletic AV, Bottini N, Mustelin T.

Autoimmunity. 2007 Sep;40(6):453-61. Review.

PMID:
17729039
17.

PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant.

Zheng P, Kissler S.

Diabetes. 2013 Mar;62(3):896-904. doi: 10.2337/db12-0929. Epub 2012 Nov 28.

18.

PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells.

Maine CJ, Marquardt K, Cheung J, Sherman LA.

J Immunol. 2014 Feb 15;192(4):1415-24. doi: 10.4049/jimmunol.1302418. Epub 2014 Jan 22.

19.

Autoimmunity in primary antibody deficiency is associated with protein tyrosine phosphatase nonreceptor type 22 (PTPN22).

Chew GY, Sinha U, Gatenby PA, DeMalmanche T, Adelstein S, Garsia R, Hissaria P, French MA, Wilson A, Whittle B, Kirkpatrick P, Riminton DS, Fulcher DA, Cook MC.

J Allergy Clin Immunol. 2013 Apr;131(4):1130-5, 1135.e1. doi: 10.1016/j.jaci.2012.06.023. Epub 2012 Jul 31.

PMID:
22857794
20.

PTPN22: setting thresholds for autoimmunity.

Gregersen PK, Lee HS, Batliwalla F, Begovich AB.

Semin Immunol. 2006 Aug;18(4):214-23. Epub 2006 May 30. Review.

PMID:
16731003

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