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Items: 1 to 20 of 82

1.

Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging.

Singh L, Brennan TA, Kim JH, Egan KP, McMillan EA, Chen Q, Hankenson KD, Zhang Y, Emerson SG, Johnson FB, Pignolo RJ.

Stem Cells. 2013 Mar;31(3):607-11. doi: 10.1002/stem.1294.

2.

Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.

Wang H, Chen Q, Lee SH, Choi Y, Johnson FB, Pignolo RJ.

Aging Cell. 2012 Aug;11(4):704-13. doi: 10.1111/j.1474-9726.2012.00838.x. Epub 2012 Jun 11.

3.

Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.

Brennan TA, Egan KP, Lindborg CM, Chen Q, Sweetwyne MT, Hankenson KD, Xie SX, Johnson FB, Pignolo RJ.

Dis Model Mech. 2014 May;7(5):583-92. doi: 10.1242/dmm.014928. Epub 2014 Mar 13.

4.

Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.

Pignolo RJ, Suda RK, McMillan EA, Shen J, Lee SH, Choi Y, Wright AC, Johnson FB.

Aging Cell. 2008 Jan;7(1):23-31. Epub 2007 Nov 20.

5.

Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage.

Singh L, Brennan TA, Russell E, Kim JH, Chen Q, Brad Johnson F, Pignolo RJ.

Bone. 2016 Apr;85:29-36. doi: 10.1016/j.bone.2016.01.014. Epub 2016 Jan 19.

6.

Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.

Saeed H, Abdallah BM, Ditzel N, Catala-Lehnen P, Qiu W, Amling M, Kassem M.

J Bone Miner Res. 2011 Jul;26(7):1494-505. doi: 10.1002/jbmr.349.

7.

Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice.

Mirsaidi A, Kleinhans KN, Rimann M, Tiaden AN, Stauber M, Rudolph KL, Richards PJ.

J Tissue Eng Regen Med. 2012 May;6(5):378-90. doi: 10.1002/term.440. Epub 2011 Jun 28.

PMID:
21710574
8.

Systemic Mesenchymal Stromal Cell Transplantation Prevents Functional Bone Loss in a Mouse Model of Age-Related Osteoporosis.

Kiernan J, Hu S, Grynpas MD, Davies JE, Stanford WL.

Stem Cells Transl Med. 2016 May;5(5):683-93. doi: 10.5966/sctm.2015-0231. Epub 2016 Mar 17.

9.
10.

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment.

Ju Z, Jiang H, Jaworski M, Rathinam C, Gompf A, Klein C, Trumpp A, Rudolph KL.

Nat Med. 2007 Jun;13(6):742-7. Epub 2007 May 7.

PMID:
17486088
11.

Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation.

Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H.

J Clin Invest. 2010 Oct;120(10):3455-65. doi: 10.1172/JCI42528. Epub 2010 Sep 27.

12.

Target disruption of ribosomal protein pNO40 accelerates aging and impairs osteogenic differentiation of mesenchymal stem cells.

Lin YM, Wu CC, Chang YC, Wu CH, Ho HL, Hu JW, Chang RC, Wang CT, Ouyang P.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):903-10. doi: 10.1016/j.bbrc.2015.12.003. Epub 2015 Dec 23.

PMID:
26721440
13.

Fate of bone marrow mesenchymal stromal cells following autologous transplantation in a rabbit model of osteonecrosis.

Sugaya H, Mishima H, Gao R, Kaul SC, Wadhwa R, Aoto K, Li M, Yoshioka T, Ogawa T, Ochiai N, Yamazaki M.

Cytotherapy. 2016 Feb;18(2):198-204. doi: 10.1016/j.jcyt.2015.10.016.

PMID:
26794712
15.

Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells.

Stenderup K, Justesen J, Clausen C, Kassem M.

Bone. 2003 Dec;33(6):919-26.

PMID:
14678851
18.

Effect of bone-marrow-derived mesenchymal stem cells on high-potential hepatocellular carcinoma in mouse models: an intervention study.

Li T, Song B, Du X, Wei Z, Huo T.

Eur J Med Res. 2013 Sep 30;18:34. doi: 10.1186/2047-783X-18-34.

19.

Critical role for Y1 receptors in mesenchymal progenitor cell differentiation and osteoblast activity.

Lee NJ, Doyle KL, Sainsbury A, Enriquez RF, Hort YJ, Riepler SJ, Baldock PA, Herzog H.

J Bone Miner Res. 2010 Aug;25(8):1736-47. doi: 10.1002/jbmr.61.

20.

Impaired therapeutic capacity of autologous stem cells in a model of type 2 diabetes.

Shin L, Peterson DA.

Stem Cells Transl Med. 2012 Feb;1(2):125-35. doi: 10.5966/sctm.2012-0031. Epub 2012 Jan 26.

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