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Items: 1 to 20 of 148

1.

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.

Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H.

J Clin Invest. 2012 Dec;122(12):4424-38. doi: 10.1172/JCI64537. Epub 2012 Nov 26.

2.

Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.

Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-7. doi: 10.1161/ATVBAHA.113.302586. Epub 2013 Dec 5. Erratum in: Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):e7.

3.

Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis.

Rahman HN, Wu H, Dong Y, Pasula S, Wen A, Sun Y, Brophy ML, Tessneer KL, Cai X, McManus J, Chang B, Kwak S, Rahman NS, Xu W, Fernandes C, Mcdaniel JM, Xia L, Smith L, Srinivasan RS, Chen H.

Circ Res. 2016 Mar 18;118(6):957-69. doi: 10.1161/CIRCRESAHA.115.307679. Epub 2016 Feb 15.

4.

Are epsins a therapeutic target for tumor angiogenesis?

Klauber-Demore N.

J Clin Invest. 2012 Dec;122(12):4341-3. doi: 10.1172/JCI66171. Epub 2012 Nov 26.

5.
6.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Epub 2015 Nov 16. Erratum in: J Clin Invest. 2016 Apr 1;126(4):1607.

7.

Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway.

Zhang J, Ye J, Ma D, Liu N, Wu H, Yu S, Sun X, Tse W, Ji C.

Carcinogenesis. 2013 Mar;34(3):667-77. doi: 10.1093/carcin/bgs386. Epub 2012 Dec 13.

PMID:
23239744
8.

Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2.

Noghero A, Perino A, Seano G, Saglio E, Lo Sasso G, Veglio F, Primo L, Hirsch E, Bussolino F, Morello F.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2280-8. doi: 10.1161/ATVBAHA.112.250621. Epub 2012 Jun 21.

9.

CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth.

Chung TW, Kim SJ, Choi HJ, Kwak CH, Song KH, Suh SJ, Kim KJ, Ha KT, Park YG, Chang YC, Chang HW, Lee YC, Kim CH.

J Mol Med (Berl). 2013 Feb;91(2):271-82. doi: 10.1007/s00109-012-0952-6. Epub 2012 Aug 31.

PMID:
22935775
10.

Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

Huang SW, Lien JC, Kuo SC, Huang TF.

Carcinogenesis. 2012 May;33(5):1022-30. doi: 10.1093/carcin/bgs127. Epub 2012 Mar 20.

PMID:
22436611
11.

Epsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer Progression.

Tessneer KL, Cai X, Pasula S, Dong Y, Liu X, Chang B, McManus J, Hahn S, Yu L, Chen H.

J Can Res Updates. 2013 Jul 1;2(3):144-150.

12.

The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis.

Herkenne S, Paques C, Nivelles O, Lion M, Bajou K, Pollenus T, Fontaine M, Carmeliet P, Martial JA, Nguyen NQ, Struman I.

Sci Signal. 2015 Nov 17;8(403):ra117. doi: 10.1126/scisignal.aaa2403. Erratum in: Sci Signal. 2015 Dec 8;8(406):er9.

PMID:
26577922
13.

Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth.

Lin MI, Yu J, Murata T, Sessa WC.

Cancer Res. 2007 Mar 15;67(6):2849-56.

14.

Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.

Chen MC, Lee CF, Huang WH, Chou TC.

Biochem Pharmacol. 2013 May 1;85(9):1278-87. doi: 10.1016/j.bcp.2013.02.009. Epub 2013 Feb 14.

PMID:
23416116
15.

Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression.

German AE, Mammoto T, Jiang E, Ingber DE, Mammoto A.

J Cell Sci. 2014 Apr 15;127(Pt 8):1672-83. doi: 10.1242/jcs.132316. Epub 2014 Feb 12.

16.

Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.

van Lessen M, Nakayama M, Kato K, Kim JM, Kaibuchi K, Adams RH.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1815-25. doi: 10.1161/ATVBAHA.115.305473. Epub 2015 Jun 11.

17.

Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling.

Qin J, Chen X, Yu-Lee LY, Tsai MJ, Tsai SY.

Cancer Res. 2010 Nov 1;70(21):8812-21. doi: 10.1158/0008-5472.CAN-10-0551. Epub 2010 Oct 26.

18.

Endothelial epsins as regulators and potential therapeutic targets of tumor angiogenesis.

Song K, Wu H, Rahman HN, Dong Y, Wen A, Brophy ML, Wong S, Kwak S, Bielenberg DR, Chen H.

Cell Mol Life Sci. 2017 Feb;74(3):393-398. doi: 10.1007/s00018-016-2347-2. Epub 2016 Aug 29. Review.

PMID:
27572288
19.

Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis.

Germain M, De Arcangelis A, Robinson SD, Baker M, Tavora B, D'Amico G, Silva R, Kostourou V, Reynolds LE, Watson A, Jones JL, Georges-Labouesse E, Hodivala-Dilke K.

J Pathol. 2010 Feb;220(3):370-81. doi: 10.1002/path.2654.

PMID:
19967723

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