Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 115


The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas.

Tiemessen MM, Baert MR, Schonewille T, Brugman MH, Famili F, Salvatori DC, Meijerink JP, Ozbek U, Clevers H, van Dongen JJ, Staal FJ.

PLoS Biol. 2012;10(11):e1001430. doi: 10.1371/journal.pbio.1001430. Epub 2012 Nov 20.


β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors.

Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA.

PLoS Genet. 2013;9(8):e1003603. doi: 10.1371/journal.pgen.1003603. Epub 2013 Aug 15.


T Cell factor 1 represses CD8+ effector T cell formation and function.

Tiemessen MM, Baert MR, Kok L, van Eggermond MC, van den Elsen PJ, Arens R, Staal FJ.

J Immunol. 2014 Dec 1;193(11):5480-7. doi: 10.4049/jimmunol.1303417. Epub 2014 Oct 29.


Cell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells.

Berga-Bolaños R, Zhu WS, Steinke FC, Xue HH, Sen JM.

Mol Immunol. 2015 Dec;68(2 Pt B):484-9. doi: 10.1016/j.molimm.2015.09.017. Epub 2015 Oct 17.


Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.

Xing S, Li F, Zeng Z, Zhao Y, Yu S, Shan Q, Li Y, Phillips FC, Maina PK, Qi HH, Liu C, Zhu J, Pope RM, Musselman CA, Zeng C, Peng W, Xue HH.

Nat Immunol. 2016 Jun;17(6):695-703. doi: 10.1038/ni.3456. Epub 2016 Apr 25.


Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.

Yu S, Li F, Xing S, Zhao T, Peng W, Xue HH.

J Biol Chem. 2016 May 20;291(21):11148-60. doi: 10.1074/jbc.M116.717801. Epub 2016 Apr 4.


From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.

Steinke FC, Xue HH.

Immunol Res. 2014 Aug;59(1-3):45-55. doi: 10.1007/s12026-014-8545-9. Review.


Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription.

Kennedy MW, Chalamalasetty RB, Thomas S, Garriock RJ, Jailwala P, Yamaguchi TP.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3545-50. doi: 10.1073/pnas.1519994113. Epub 2016 Mar 11.


Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas.

Spaulding C, Reschly EJ, Zagort DE, Yashiro-Ohtani Y, Beverly LJ, Capobianco A, Pear WS, Kee BL.

Blood. 2007 Oct 1;110(7):2650-8. Epub 2007 Jun 21.


Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression.

Wallmen B, Schrempp M, Hecht A.

Nucleic Acids Res. 2012 Oct;40(19):9455-69. doi: 10.1093/nar/gks690. Epub 2012 Aug 2.


Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.

Xu Z, Xing S, Shan Q, Gullicksrud JA, Bair TB, Du Y, Liu C, Xue HH.

J Immunol. 2017 May 1;198(9):3404-3409. doi: 10.4049/jimmunol.1602139. Epub 2017 Mar 27.


The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

Yu S, Zhou X, Steinke FC, Liu C, Chen SC, Zagorodna O, Jing X, Yokota Y, Meyerholz DK, Mullighan CG, Knudson CM, Zhao DM, Xue HH.

Immunity. 2012 Nov 16;37(5):813-26. doi: 10.1016/j.immuni.2012.08.009. Epub 2012 Oct 25. Erratum in: Immunity. 2014 Jan 16;40(1):166.


Differential expression of LEF1/TCFs family members in colonic carcinogenesis.

Han W, He L, Cao B, Zhao X, Zhang K, Li Y, Beck P, Zhou Z, Tian Y, Cheng S, Wang H.

Mol Carcinog. 2017 Nov;56(11):2372-2381. doi: 10.1002/mc.22530. Epub 2017 May 22.


Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.

Staal FJ, Weerkamp F, Baert MR, van den Burg CM, van Noort M, de Haas EF, van Dongen JJ.

J Immunol. 2004 Jan 15;172(2):1099-108.


Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus.

De Jaime-Soguero A, Aulicino F, Ertaylan G, Griego A, Cerrato A, Tallam A, Del Sol A, Cosma MP, Lluis F.

PLoS Genet. 2017 Mar 27;13(3):e1006682. doi: 10.1371/journal.pgen.1006682. eCollection 2017 Mar.


Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.

Boras-Granic K, Chang H, Grosschedl R, Hamel PA.

Dev Biol. 2006 Jul 1;295(1):219-31. Epub 2006 Apr 3.


Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development.

Kuwahara A, Sakai H, Xu Y, Itoh Y, Hirabayashi Y, Gotoh Y.

PLoS One. 2014 May 15;9(5):e94408. doi: 10.1371/journal.pone.0094408. eCollection 2014.


Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex.

Kumar A, Chalamalasetty RB, Kennedy MW, Thomas S, Inala SN, Garriock RJ, Yamaguchi TP.

Mol Cell Biol. 2016 May 31;36(12):1793-802. doi: 10.1128/MCB.01010-15. Print 2016 Jun 15.


A network of high-mobility group box transcription factors programs innate interleukin-17 production.

Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J; Immunological Genome Project Consortium.

Immunity. 2013 Apr 18;38(4):681-93. doi: 10.1016/j.immuni.2013.01.010. Epub 2013 Apr 4.


Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2.

Mallory MJ, Jackson J, Weber B, Chi A, Heyd F, Lynch KW.

Mol Cell Biol. 2011 Jun;31(11):2184-95. doi: 10.1128/MCB.05170-11. Epub 2011 Mar 28.

Supplemental Content

Support Center