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Items: 1 to 20 of 116


Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation.

Wu Y, DiMaggio PA Jr, Perlman DH, Zakian VA, Garcia BA.

J Proteome Res. 2013 Jan 4;12(1):316-27. doi: 10.1021/pr300408v. Epub 2012 Dec 13.


Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13.

Tseng SF, Shen ZJ, Tsai HJ, Lin YH, Teng SC.

Nucleic Acids Res. 2009 Jun;37(11):3602-11. doi: 10.1093/nar/gkp235. Epub 2009 Apr 9.


Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13.

Gao H, Toro TB, Paschini M, Braunstein-Ballew B, Cervantes RB, Lundblad V.

Genetics. 2010 Dec;186(4):1147-59. doi: 10.1534/genetics.110.122044. Epub 2010 Sep 13.


Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication.

Liu CC, Gopalakrishnan V, Poon LF, Yan T, Li S.

Mol Cell Biol. 2014 Jan;34(1):57-70. doi: 10.1128/MCB.01235-13. Epub 2013 Oct 28.


SUMOylation regulates telomere length homeostasis by targeting Cdc13.

Hang LE, Liu X, Cheung I, Yang Y, Zhao X.

Nat Struct Mol Biol. 2011 Jul 10;18(8):920-6. doi: 10.1038/nsmb.2100.


A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle.

Tucey TM, Lundblad V.

Biochemistry. 2013 Feb 19;52(7):1131-3. doi: 10.1021/bi3015218. Epub 2013 Feb 7. Erratum in: Biochemistry. 2013 Jul 23;52(29):5027.


Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, Blackburn EH.

Cell. 2009 Jan 9;136(1):50-61. doi: 10.1016/j.cell.2008.11.027.


The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro.

Wu Y, Zakian VA.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20362-9. doi: 10.1073/pnas.1100281108. Epub 2011 Oct 3.


New function of CDC13 in positive telomere length regulation.

Meier B, Driller L, Jaklin S, Feldmann HM.

Mol Cell Biol. 2001 Jul;21(13):4233-45.


Est1p as a cell cycle-regulated activator of telomere-bound telomerase.

Taggart AK, Teng SC, Zakian VA.

Science. 2002 Aug 9;297(5583):1023-6.


PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase.

Shen ZJ, Hsu PH, Su YT, Yang CW, Kao L, Tseng SF, Tsai MD, Teng SC.

Nat Commun. 2014 Nov 12;5:5312. doi: 10.1038/ncomms6312. Erratum in: Nat Commun. 2015;6:7819.


Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.

Puglisi A, Bianchi A, Lemmens L, Damay P, Shore D.

EMBO J. 2008 Sep 3;27(17):2328-39. doi: 10.1038/emboj.2008.158.


Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres.

Chan A, Boulé JB, Zakian VA.

PLoS Genet. 2008 Oct;4(10):e1000236. doi: 10.1371/journal.pgen.1000236. Epub 2008 Oct 24.


S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association.

Goudsouzian LK, Tuzon CT, Zakian VA.

Mol Cell. 2006 Nov 17;24(4):603-10.


Est1 and Cdc13 as comediators of telomerase access.

Evans SK, Lundblad V.

Science. 1999 Oct 1;286(5437):117-20.

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