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Items: 1 to 20 of 143

1.

Salvianolic acid B inhibits the amyloid formation of human islet amyloid polypeptide and protects pancreatic beta-cells against cytotoxicity.

Cheng B, Gong H, Li X, Sun Y, Chen H, Zhang X, Wu Q, Zheng L, Huang K.

Proteins. 2013 Apr;81(4):613-21. doi: 10.1002/prot.24216. Epub 2012 Dec 24.

PMID:
23180621
2.

Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide.

Cheng B, Gong H, Li X, Sun Y, Zhang X, Chen H, Liu X, Zheng L, Huang K.

Biochem Biophys Res Commun. 2012 Mar 16;419(3):495-9. doi: 10.1016/j.bbrc.2012.02.042. Epub 2012 Feb 14.

PMID:
22366091
3.

Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus.

Cheng B, Liu X, Gong H, Huang L, Chen H, Zhang X, Li C, Yang M, Ma B, Jiao L, Zheng L, Huang K.

J Agric Food Chem. 2011 Dec 28;59(24):13147-55. doi: 10.1021/jf201702h. Epub 2011 Nov 21.

PMID:
22059381
4.

Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes.

Gong H, Zhang X, Cheng B, Sun Y, Li C, Li T, Zheng L, Huang K.

PLoS One. 2013;8(1):e54198. doi: 10.1371/journal.pone.0054198. Epub 2013 Jan 23.

5.

In vitro evaluation of hypoglycemic agents to target human islet amyloid polypeptide: a key protein involved in amyloid deposition and beta-cell loss.

Fortin JS, Benoit-Biancamano MO.

Can J Diabetes. 2015 Oct;39(5):373-82. doi: 10.1016/j.jcjd.2015.01.291. Epub 2015 Apr 7.

PMID:
25862064
6.

Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus.

Khemtémourian L, Killian JA, Höppener JW, Engel MF.

Exp Diabetes Res. 2008;2008:421287. doi: 10.1155/2008/421287. Review.

7.

Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis.

Fan R, Li X, Gu X, Chan JC, Xu G.

Diabetes Obes Metab. 2010 Sep;12(9):815-24. doi: 10.1111/j.1463-1326.2010.01238.x.

PMID:
20649634
8.

Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity.

Meier DT, Tu LH, Zraika S, Hogan MF, Templin AT, Hull RL, Raleigh DP, Kahn SE.

J Biol Chem. 2015 Dec 18;290(51):30475-85. doi: 10.1074/jbc.M115.676692. Epub 2015 Oct 19.

9.

Geniposide protects pancreatic INS-1E β cells from hIAPP-induced cell damage: potential involvement of insulin degrading-enzyme.

Zhang Y, Yin F, Liu J, Wang Y.

Cell Biol Int. 2015 Apr;39(4):373-8. doi: 10.1002/cbin.10394. Epub 2014 Nov 10.

PMID:
25319222
10.

Human IAPP amyloidogenic properties and pancreatic β-cell death.

Fernández MS.

Cell Calcium. 2014 Nov;56(5):416-27. doi: 10.1016/j.ceca.2014.08.011. Epub 2014 Aug 27. Review.

PMID:
25224501
11.

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes.

Kim J, Cheon H, Jeong YT, Quan W, Kim KH, Cho JM, Lim YM, Oh SH, Jin SM, Kim JH, Lee MK, Kim S, Komatsu M, Kang SW, Lee MS.

J Clin Invest. 2014 Aug;124(8):3311-24. doi: 10.1172/JCI69625. Epub 2014 Jul 18.

12.

Analysis of the ability of pramlintide to inhibit amyloid formation by human islet amyloid polypeptide reveals a balance between optimal recognition and reduced amyloidogenicity.

Wang H, Ridgway Z, Cao P, Ruzsicska B, Raleigh DP.

Biochemistry. 2015 Nov 10;54(44):6704-11. doi: 10.1021/acs.biochem.5b00567. Epub 2015 Oct 30.

13.

Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus.

Caillon L, Hoffmann AR, Botz A, Khemtemourian L.

J Diabetes Res. 2016;2016:5639875. doi: 10.1155/2016/5639875. Epub 2015 Nov 9. Review.

14.
15.

One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice.

Aston-Mourney K, Subramanian SL, Zraika S, Samarasekera T, Meier DT, Goldstein LC, Hull RL.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E475-84. doi: 10.1152/ajpendo.00025.2013. Epub 2013 Jun 4.

16.

Proanthocyanidins are the major anti-diabetic components of cinnamon water extract.

Jiao L, Zhang X, Huang L, Gong H, Cheng B, Sun Y, Li Y, Liu Q, Zheng L, Huang K.

Food Chem Toxicol. 2013 Jun;56:398-405. doi: 10.1016/j.fct.2013.02.049. Epub 2013 Mar 7.

PMID:
23499750
17.

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

Subramanian SL, Hull RL, Zraika S, Aston-Mourney K, Udayasankar J, Kahn SE.

Diabetologia. 2012 Jan;55(1):166-74. doi: 10.1007/s00125-011-2338-7. Epub 2011 Oct 26.

18.

Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway.

Gurlo T, Ryazantsev S, Huang CJ, Yeh MW, Reber HA, Hines OJ, O'Brien TD, Glabe CG, Butler PC.

Am J Pathol. 2010 Feb;176(2):861-9. doi: 10.2353/ajpath.2010.090532. Epub 2009 Dec 30.

19.

Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide-insulin interactions.

Susa AC, Wu C, Bernstein SL, Dupuis NF, Wang H, Raleigh DP, Shea JE, Bowers MT.

J Am Chem Soc. 2014 Sep 17;136(37):12912-9. doi: 10.1021/ja504031d. Epub 2014 Sep 4.

20.

Binding of islet amyloid polypeptide to supported lipid bilayers and amyloid aggregation at the membranes.

Sasahara K, Morigaki K, Okazaki T, Hamada D.

Biochemistry. 2012 Sep 4;51(35):6908-19. doi: 10.1021/bi300542g. Epub 2012 Aug 23.

PMID:
22876830

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