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Items: 1 to 20 of 106

1.

T-cell death following immune activation is mediated by mitochondria-localized SARM.

Panneerselvam P, Singh LP, Selvarajan V, Chng WJ, Ng SB, Tan NS, Ho B, Chen J, Ding JL.

Cell Death Differ. 2013 Mar;20(3):478-89. doi: 10.1038/cdd.2012.144.

2.

MEK-ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death.

Tomiyama A, Tachibana K, Suzuki K, Seino S, Sunayama J, Matsuda KI, Sato A, Matsumoto Y, Nomiya T, Nemoto K, Yamashita H, Kayama T, Ando K, Kitanaka C.

Cell Death Dis. 2010 Jul 29;1:e60. doi: 10.1038/cddis.2010.37.

3.

UXT plays dual opposing roles on SARM-induced apoptosis.

Sethurathinam S, Singh LP, Panneerselvam P, Byrne B, Ding JL.

FEBS Lett. 2013 Oct 11;587(20):3296-302. doi: 10.1016/j.febslet.2013.08.033.

4.

Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence.

Panneerselvam P, Singh LP, Ho B, Chen J, Ding JL.

Biochem J. 2012 Mar 1;442(2):263-71. doi: 10.1042/BJ20111653.

PMID:
22145856
5.

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

Carty M, Goodbody R, Schröder M, Stack J, Moynagh PN, Bowie AG.

Nat Immunol. 2006 Oct;7(10):1074-81.

PMID:
16964262
6.

Eriocalyxin B induces apoptosis in lymphoma cells through multiple cellular signaling pathways.

Zhang YW, Jiang XX, Chen QS, Shi WY, Wang L, Sun HD, Shen ZX, Chen Z, Chen SJ, Zhao WL.

Exp Hematol. 2010 Mar;38(3):191-201. doi: 10.1016/j.exphem.2009.12.005.

PMID:
20045442
7.
8.

SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.

Peng J, Yuan Q, Lin B, Panneerselvam P, Wang X, Luan XL, Lim SK, Leung BP, Ho B, Ding JL.

Eur J Immunol. 2010 Jun;40(6):1738-47. doi: 10.1002/eji.200940034.

10.

Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL.

Manicassamy S, Gupta S, Huang Z, Sun Z.

J Immunol. 2006 Jun 1;176(11):6709-16.

11.

Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.

El Fajoui Z, Toscano F, Jacquemin G, Abello J, Scoazec JY, Micheau O, Saurin JC.

Gastroenterology. 2011 Aug;141(2):663-73. doi: 10.1053/j.gastro.2011.04.055.

PMID:
21683075
12.

Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway.

Handrick R, Ontikatze T, Bauer KD, Freier F, Rübel A, Dürig J, Belka C, Jendrossek V.

Mol Cancer Ther. 2010 Sep;9(9):2497-510. doi: 10.1158/1535-7163.MCT-10-0051.

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14.

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis.

Allagnat F, Cunha D, Moore F, Vanderwinden JM, Eizirik DL, Cardozo AK.

Cell Death Differ. 2011 Feb;18(2):328-37. doi: 10.1038/cdd.2010.105.

16.

TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L).

Kim JJ, Lee SB, Park JK, Yoo YD.

Cell Death Differ. 2010 Sep;17(9):1420-34. doi: 10.1038/cdd.2010.19.

17.

NF-kappaB protects Behçet's disease T cells against CD95-induced apoptosis up-regulating antiapoptotic proteins.

Todaro M, Zerilli M, Triolo G, Iovino F, Patti M, Accardo-Palumbo A, di Gaudio F, Turco MC, Petrella A, de Maria R, Stassi G.

Arthritis Rheum. 2005 Jul;52(7):2179-91.

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p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.

Müer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dörken B, Daniel PT, Hemmati P.

J Biol Chem. 2012 May 18;287(21):17343-52. doi: 10.1074/jbc.M111.314898.

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