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Items: 1 to 20 of 298

1.

Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: synthesis and in vitro antimicrobial and cytotoxic activities.

Vega-Pérez JM, Periñán I, Argandoña M, Vega-Holm M, Palo-Nieto C, Burgos-Morón E, López-Lázaro M, Vargas C, Nieto JJ, Iglesias-Guerra F.

Eur J Med Chem. 2012 Dec;58:591-612. doi: 10.1016/j.ejmech.2012.10.042. Epub 2012 Nov 1.

2.

Synthesis, antimicrobial and cytotoxicity study of 1,3-disubstituted-1H-naphtho[1,2-e][1,3]oxazines.

Verma V, Singh K, Kumar D, Klapötke TM, Stierstorfer J, Narasimhan B, Qazi AK, Hamid A, Jaglan S.

Eur J Med Chem. 2012 Oct;56:195-202. doi: 10.1016/j.ejmech.2012.08.018. Epub 2012 Aug 23.

PMID:
22982123
3.

Synthesis and biological evaluation of some novel polysubstituted pyrimidine derivatives as potential antimicrobial and anticancer agents.

Rostom SA, Ashour HM, Abd El Razik HA.

Arch Pharm (Weinheim). 2009 May;342(5):299-310. doi: 10.1002/ardp.200800223.

PMID:
19415663
4.

Synthesis and biological evaluation of some 2,4,5-trisubstituted thiazole derivatives as potential antimicrobial and anticancer agents.

Al-Saadi MS, Faidallah HM, Rostom SA.

Arch Pharm (Weinheim). 2008 Jul;341(7):424-34. doi: 10.1002/ardp.200800026.

PMID:
18574850
5.

Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives.

Sreelatha T, Kandhasamy S, Dinesh R, Shruthy S, Shweta S, Mukesh D, Karunagaran D, Balaji R, Mathivanan N, Perumal PT.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3647-51. doi: 10.1016/j.bmcl.2014.04.080. Epub 2014 May 20.

PMID:
24913712
6.

Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: synthesis and in vitro biological evaluation. Part 1.

Bozorov K, Ma HR, Zhao JY, Zhao HQ, Chen H, Bobakulov K, Xin XL, Elmuradov B, Shakhidoyatov K, Aisa HA.

Eur J Med Chem. 2014 Sep 12;84:739-45. doi: 10.1016/j.ejmech.2014.07.065. Epub 2014 Jul 21.

PMID:
25064350
7.

Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles.

El-Gohary NS, Shaaban MI.

Eur J Med Chem. 2013 May;63:185-95. doi: 10.1016/j.ejmech.2013.02.010. Epub 2013 Feb 18.

PMID:
23474904
8.

Synthesis, antimicrobial activity and structure-activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives.

Sharma M, Joshi P, Kumar N, Joshi S, Rohilla RK, Roy N, Rawat DS.

Eur J Med Chem. 2011 Feb;46(2):480-7. doi: 10.1016/j.ejmech.2010.11.027. Epub 2010 Nov 24.

PMID:
21163555
9.

New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation.

Patel NB, Purohit AC, Rajani DP, Moo-Puc R, Rivera G.

Eur J Med Chem. 2013 Apr;62:677-87. doi: 10.1016/j.ejmech.2012.12.055. Epub 2013 Jan 23.

PMID:
23434641
10.

Synthesis and initial biological evaluation of substituted 1-phenylamino-2-thio-4,5-dimethyl-1H-imidazole derivatives.

Yurttaş L, Duran M, Demirayak Ş, Gençer HK, Tunalı Y.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6764-8. doi: 10.1016/j.bmcl.2013.10.024. Epub 2013 Oct 22.

PMID:
24176398
11.

Hydrazones of 2-aryl-quinoline-4-carboxylic acid hydrazides: synthesis and preliminary evaluation as antimicrobial agents.

Metwally KA, Abdel-Aziz LM, Lashine el-SM, Husseiny MI, Badawy RH.

Bioorg Med Chem. 2006 Dec 15;14(24):8675-82. Epub 2006 Sep 1.

PMID:
16949294
12.

Mixed-ligand Cu(II)-vanillin Schiff base complexes; effect of coligands on their DNA binding, DNA cleavage, SOD mimetic and anticancer activity.

Tabassum S, Amir S, Arjmand F, Pettinari C, Marchetti F, Masciocchi N, Lupidi G, Pettinari R.

Eur J Med Chem. 2013 Feb;60:216-32. doi: 10.1016/j.ejmech.2012.08.019. Epub 2012 Aug 23.

PMID:
23291123
13.

Synthesis of certain 2-substituted-1H-benzimidazole derivatives as antimicrobial and cytotoxic agents.

Taher AT, Khalil NA, Ahmed EM, Ragab YM.

Chem Pharm Bull (Tokyo). 2012;60(6):778-84.

14.

New alpha-(N)-heterocyclichydrazones: evaluation of anticancer, anti-HIV and antimicrobial activity.

Savini L, Chiasserini L, Travagli V, Pellerano C, Novellino E, Cosentino S, Pisano MB.

Eur J Med Chem. 2004 Feb;39(2):113-22.

PMID:
14987820
15.

Synthesis and biological activity of new 1,3-dioxolanes as potential antibacterial and antifungal compounds.

Küçük HB, Yusufoğlu A, Mataracı E, Döşler S.

Molecules. 2011 Aug 10;16(8):6806-15. doi: 10.3390/molecules16086806.

16.

Synthesis, characterization and in vitro biological evaluation of some novel diarylsulfonylureas as potential cytotoxic and antimicrobial agents.

Avupati VR, Yejella RP, Guntuku G, Gunta P.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1031-5. doi: 10.1016/j.bmcl.2011.11.125. Epub 2011 Dec 7.

PMID:
22200598
17.

Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives.

Fadda AA, Afsah el-SM, Awad RS.

Eur J Med Chem. 2013 Feb;60:421-30. doi: 10.1016/j.ejmech.2012.11.017. Epub 2012 Nov 20.

PMID:
23318903
18.

Synthesis, antimicrobial activity and cytotoxicity of some new carbazole derivatives.

Kaplancikli ZA, Yurttaş L, Turan-Zitouni G, Özdemir A, Özic R, Ulusoylar-Yildirim Ş.

J Enzyme Inhib Med Chem. 2012 Dec;27(6):868-74. doi: 10.3109/14756366.2011.622273. Epub 2011 Oct 15.

PMID:
21999633
19.

Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities.

Kumar V, Kaur K, Karelia DN, Beniwal V, Gupta GK, Sharma AK, Gupta AK.

Eur J Med Chem. 2014 Jun 23;81:267-76. doi: 10.1016/j.ejmech.2014.05.004. Epub 2014 May 6.

PMID:
24849271
20.

Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells.

Emirdağ-Öztürk S, Karayıldırım T, Çapcı-Karagöz A, Alankuş-Çalışkan Ö, Özmen A, Poyrazoğlu-Çoban E.

Eur J Med Chem. 2014 Jul 23;82:565-73. doi: 10.1016/j.ejmech.2014.05.084. Epub 2014 Jun 7.

PMID:
24941130

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