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Items: 1 to 20 of 178

1.

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice.

Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B.

Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21.

2.

IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function.

Waddell A, Vallance JE, Moore PD, Hummel AT, Wu D, Shanmukhappa SK, Fei L, Washington MK, Minar P, Coburn LA, Nakae S, Wilson KT, Denson LA, Hogan SP, Rosen MJ.

Inflamm Bowel Dis. 2015 Dec;21(12):2737-46. doi: 10.1097/MIB.0000000000000532.

3.

Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis.

Terc J, Hansen A, Alston L, Hirota SA.

Eur J Pharm Sci. 2014 May 13;55:12-9. doi: 10.1016/j.ejps.2014.01.007. Epub 2014 Jan 29.

PMID:
24486481
4.

Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis.

Pastorelli L, Garg RR, Hoang SB, Spina L, Mattioli B, Scarpa M, Fiocchi C, Vecchi M, Pizarro TT.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8017-22. doi: 10.1073/pnas.0912678107. Epub 2010 Apr 12.

5.

Protective role of 1,25(OH)2 vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice.

Zhao H, Zhang H, Wu H, Li H, Liu L, Guo J, Li C, Shih DQ, Zhang X.

BMC Gastroenterol. 2012 May 30;12:57.

6.

IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo.

Scheibe K, Backert I, Wirtz S, Hueber A, Schett G, Vieth M, Probst HC, Bopp T, Neurath MF, Neufert C.

Gut. 2017 May;66(5):823-838. doi: 10.1136/gutjnl-2015-310374. Epub 2016 Jan 18.

PMID:
26783184
7.

Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease.

Beltrán CJ, Núñez LE, Díaz-Jiménez D, Farfan N, Candia E, Heine C, López F, González MJ, Quera R, Hermoso MA.

Inflamm Bowel Dis. 2010 Jul;16(7):1097-107. doi: 10.1002/ibd.21175.

PMID:
20014018
8.

The IL-33/ST2 axis: yet another therapeutic target in inflammatory bowel disease?

Salas A.

Gut. 2013 Oct;62(10):1392-3. doi: 10.1136/gutjnl-2012-303920. Epub 2013 Jan 11. No abstract available.

PMID:
23315502
9.

Activation of Epithelial Signal Transducer and Activator of Transcription 1 by Interleukin 28 Controls Mucosal Healing in Mice With Colitis and Is Increased in Mucosa of Patients With Inflammatory Bowel Disease.

Chiriac MT, Buchen B, Wandersee A, Hundorfean G, Günther C, Bourjau Y, Doyle SE, Frey B, Ekici AB, Büttner C, Weigmann B, Atreya R, Wirtz S, Becker C, Siebler J, Neurath MF.

Gastroenterology. 2017 Jul;153(1):123-138.e8. doi: 10.1053/j.gastro.2017.03.015. Epub 2017 Mar 23.

PMID:
28342759
10.

The matricellular protein CCN1 promotes mucosal healing in murine colitis through IL-6.

Choi JS, Kim KH, Lau LF.

Mucosal Immunol. 2015 Nov;8(6):1285-96. doi: 10.1038/mi.2015.19. Epub 2015 Mar 25.

11.

Interleukin-33 exacerbates acute colitis via interleukin-4 in mice.

Pushparaj PN, Li D, Komai-Koma M, Guabiraba R, Alexander J, McSharry C, Xu D.

Immunology. 2013 Sep;140(1):70-7. doi: 10.1111/imm.12111.

12.

Interleukin-34 Induces Cc-chemokine Ligand 20 in Gut Epithelial Cells.

Franzè E, Marafini I, De Simone V, Monteleone I, Caprioli F, Colantoni A, Ortenzi A, Crescenzi F, Izzo R, Sica G, Sileri P, Rossi P, Pallone F, Monteleone G.

J Crohns Colitis. 2016 Jan;10(1):87-94. doi: 10.1093/ecco-jcc/jjv181. Epub 2015 Oct 8.

PMID:
26449789
13.

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR.

Gastroenterology. 2013 Aug;145(2):407-15. doi: 10.1053/j.gastro.2013.04.011. Epub 2013 Apr 22.

14.

Chloride channel ClC-2 is a key factor in the development of DSS-induced murine colitis.

Nighot P, Young K, Nighot M, Rawat M, Sung EJ, Maharshak N, Plevy SE, Ma T, Blikslager A.

Inflamm Bowel Dis. 2013 Dec;19(13):2867-77. doi: 10.1097/MIB.0b013e3182a82ae9.

15.

Epidermal growth factor is a critical regulator of the cytokine IL-33 in intestinal epithelial cells.

Islam MS, Horiguchi K, Iino S, Kaji N, Mikawa S, Hori M, Ozaki H.

Br J Pharmacol. 2016 Aug;173(16):2532-42. doi: 10.1111/bph.13535. Epub 2016 Jul 19.

16.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
17.

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier.

Kong J, Zhang Z, Musch MW, Ning G, Sun J, Hart J, Bissonnette M, Li YC.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G208-16. Epub 2007 Oct 25.

18.

Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice.

Bersudsky M, Luski L, Fishman D, White RM, Ziv-Sokolovskaya N, Dotan S, Rider P, Kaplanov I, Aychek T, Dinarello CA, Apte RN, Voronov E.

Gut. 2014 Apr;63(4):598-609. doi: 10.1136/gutjnl-2012-303329. Epub 2013 Jun 21.

PMID:
23793223
20.

Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease.

Neves AR, Castelo-Branco MT, Figliuolo VR, Bernardazzi C, Buongusto F, Yoshimoto A, Nanini HF, Coutinho CM, Carneiro AJ, Coutinho-Silva R, de Souza HS.

Inflamm Bowel Dis. 2014 Mar;20(3):444-57. doi: 10.1097/01.MIB.0000441201.10454.06.

PMID:
24412990

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