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Items: 1 to 20 of 84

1.

[How ApoE regulates blood-brain barrier integrity].

Gosselet F.

Med Sci (Paris). 2012 Nov;28(11):920-3. doi: 10.1051/medsci/20122811006. Epub 2012 Nov 12. French. No abstract available.

2.

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV.

Nature. 2012 May 16;485(7399):512-6. doi: 10.1038/nature11087.

3.

Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model.

Nishitsuji K, Hosono T, Nakamura T, Bu G, Michikawa M.

J Biol Chem. 2011 May 20;286(20):17536-42. doi: 10.1074/jbc.M111.225532. Epub 2011 Apr 6.

4.

Apolipoprotein E and Alzheimer disease.

Huang Y.

Neurology. 2006 Jan 24;66(2 Suppl 1):S79-85.

PMID:
16432152
5.
6.

Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.

Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, Hale J, Liu F, Hunter JM, Paul SM.

J Neurosci. 2009 Mar 18;29(11):3603-12. doi: 10.1523/JNEUROSCI.5302-08.2009.

7.
8.

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM.

J Neurosci. 2005 Mar 16;25(11):2803-10.

10.

Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease.

Zlokovic BV.

JAMA Neurol. 2013 Apr;70(4):440-4. doi: 10.1001/jamaneurol.2013.2152. Review.

11.

Alzheimer's disease. Bad for the heart, bad for the mind?

Marx J.

Science. 2001 Oct 19;294(5542):508-9. No abstract available.

PMID:
11641483
12.

Cholesterol and apoe: a target for Alzheimer's disease therapeutics.

Fenili D, McLaurin J.

Curr Drug Targets CNS Neurol Disord. 2005 Oct;4(5):553-67. Review.

PMID:
16266288
13.

Apolipoprotein E genotype and alpha-tocopherol modulate amyloid precursor protein metabolism and cell cycle regulation.

Huebbe P, Schaffer S, Jofre-Monseny L, Boesch-Saadatmandi C, Minihane AM, Müller WE, Eckert GP, Rimbach G.

Mol Nutr Food Res. 2007 Dec;51(12):1510-7.

PMID:
18030662
14.

Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein.

Irizarry MC, Deng A, Lleo A, Berezovska O, Von Arnim CA, Martin-Rehrmann M, Manelli A, LaDu MJ, Hyman BT, Rebeck GW.

J Neurochem. 2004 Sep;90(5):1132-43.

15.

ApoE: crossroads between Alzheimer's disease and atherosclerosis.

Stojakovic T, Scharnagl H, März W.

Semin Vasc Med. 2004 Aug;4(3):279-85. Review.

PMID:
15630629
16.

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM.

Neurobiol Dis. 2002 Apr;9(3):305-18.

PMID:
11950276
17.

Cell biology of the beta-amyloid precursor protein and the genetics of Alzheimer's disease.

Selkoe DJ.

Cold Spring Harb Symp Quant Biol. 1996;61:587-96. Review. No abstract available.

PMID:
9246485
18.

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM.

J Neurosci. 2002 Dec 1;22(23):10083-7.

19.

Apolipoprotein E and cognitive performance.

Raber J, Wong D, Yu GQ, Buttini M, Mahley RW, Pitas RE, Mucke L.

Nature. 2000 Mar 23;404(6776):352-4. No abstract available.

PMID:
10746713
20.

Characterization of transgenic mice expressing apolipoprotein E4(C112R) and apolipoprotein E4(L28P; C112R).

Huber G, März W, Martin JR, Malherbe P, Richards JG, Sueoka N, Ohm T, Hoffmann MM.

Neuroscience. 2000;101(1):211-8.

PMID:
11068149

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