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Items: 1 to 20 of 273


Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway.

Yang J, Liao D, Chen C, Liu Y, Chuang TH, Xiang R, Markowitz D, Reisfeld RA, Luo Y.

Stem Cells. 2013 Feb;31(2):248-58. doi: 10.1002/stem.1281.


Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

Hsu HS, Huang PI, Chang YL, Tzao C, Chen YW, Shih HC, Hung SC, Chen YC, Tseng LM, Chiou SH.

Cancer. 2011 Jul 1;117(13):2970-85. doi: 10.1002/cncr.25869. Epub 2011 Jan 10.


Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.

Alberti L, Losi L, Leyvraz S, Benhattar J.

PLoS One. 2015 Jul 17;10(7):e0132977. doi: 10.1371/journal.pone.0132977. eCollection 2015.


CD133+ subpopulation of the HT1080 human fibrosarcoma cell line exhibits cancer stem-like characteristics.

Feng BH, Liu AG, Gu WG, Deng L, Cheng XG, Tong TJ, Zhang HZ.

Oncol Rep. 2013 Aug;30(2):815-23. doi: 10.3892/or.2013.2486. Epub 2013 May 23.


Multiple pluripotent stem cell markers in human anaplastic thyroid cancer: the putative upstream role of SOX2.

Carina V, Zito G, Pizzolanti G, Richiusa P, Criscimanna A, Rodolico V, Tomasello L, Pitrone M, Arancio W, Giordano C.

Thyroid. 2013 Jul;23(7):829-37. doi: 10.1089/thy.2012.0372. Epub 2013 Jun 21.


Effect of bisphenol A on the EGFR-STAT3 pathway in MCF-7 breast cancer cells.

Zhang W, Fang Y, Shi X, Zhang M, Wang X, Tan Y.

Mol Med Rep. 2012 Jan;5(1):41-7. doi: 10.3892/mmr.2011.583. Epub 2011 Sep 9.


MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer.

Jiang J, Li Z, Yu C, Chen M, Tian S, Sun C.

Cancer Lett. 2015 Jan 28;356(2 Pt B):962-70. doi: 10.1016/j.canlet.2014.11.007. Epub 2014 Nov 10.


Blockade of Hedgehog Signaling Synergistically Increases Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Cell Lines.

Bai XY, Zhang XC, Yang SQ, An SJ, Chen ZH, Su J, Xie Z, Gou LY, Wu YL.

PLoS One. 2016 Mar 4;11(3):e0149370. doi: 10.1371/journal.pone.0149370. eCollection 2016.


VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.

Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam DJ, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton CJ, Slingerland JM.

Oncogene. 2015 Jun 11;34(24):3107-19. doi: 10.1038/onc.2014.257. Epub 2014 Aug 25.


Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer.

Kuo HY, Hsu HT, Chen YC, Chang YW, Liu FT, Wu CW.

Glycobiology. 2016 Feb;26(2):155-65. doi: 10.1093/glycob/cwv088. Epub 2015 Oct 6.


Reduced tumorigenicity and drug resistance through the downregulation of octamer-binding protein 4 and Nanog transcriptional factor expression in human breast stem cells.

Huang ZJ, You J, Luo WY, Chen BS, Feng QZ, Wu BL, Jiang L, Luo Q.

Mol Med Rep. 2015 Mar;11(3):1647-54. doi: 10.3892/mmr.2014.2972. Epub 2014 Nov 18.


Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma.

Fan QM, Jing YY, Yu GF, Kou XR, Ye F, Gao L, Li R, Zhao QD, Yang Y, Lu ZH, Wei LX.

Cancer Lett. 2014 Oct 1;352(2):160-8. doi: 10.1016/j.canlet.2014.05.008. Epub 2014 Jun 2.


Cleaved CD44 intracellular domain supports activation of stemness factors and promotes tumorigenesis of breast cancer.

Cho Y, Lee HW, Kang HG, Kim HY, Kim SJ, Chun KH.

Oncotarget. 2015 Apr 20;6(11):8709-21.


CK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancer.

Lu H, Yan C, Quan XX, Yang X, Zhang J, Bian Y, Chen Z, Van Waes C.

Neoplasia. 2014 Oct 23;16(10):789-800. doi: 10.1016/j.neo.2014.08.014. eCollection 2014 Oct.


STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits.

Chung SS, Giehl N, Wu Y, Vadgama JV.

Int J Oncol. 2014 Feb;44(2):403-11. doi: 10.3892/ijo.2013.2195. Epub 2013 Nov 29.


Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma.

Ma L, Zhang G, Miao XB, Deng XB, Wu Y, Liu Y, Jin ZR, Li XQ, Liu QZ, Sun DX, Testa JR, Yao KT, Xiao GH.

FEBS J. 2013 May;280(9):2027-41. doi: 10.1111/febs.12226. Epub 2013 Apr 8.


Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells.

Wan S, Zhao E, Kryczek I, Vatan L, Sadovskaya A, Ludema G, Simeone DM, Zou W, Welling TH.

Gastroenterology. 2014 Dec;147(6):1393-404. doi: 10.1053/j.gastro.2014.08.039. Epub 2014 Aug 30.


Exposure of tumor-associated macrophages to apoptotic MCF-7 cells promotes breast cancer growth and metastasis.

Zhou N, Zhang Y, Zhang X, Lei Z, Hu R, Li H, Mao Y, Wang X, Irwin DM, Niu G, Tan H.

Int J Mol Sci. 2015 May 26;16(6):11966-82. doi: 10.3390/ijms160611966.

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