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Items: 1 to 20 of 108

1.

Garcinia xanthones as orally active antitumor agents.

Zhang X, Li X, Sun H, Wang X, Zhao L, Gao Y, Liu X, Zhang S, Wang Y, Yang Y, Zeng S, Guo Q, You Q.

J Med Chem. 2013 Jan 10;56(1):276-92. doi: 10.1021/jm301593r. Epub 2012 Dec 31.

PMID:
23167526
2.

Novel natural-product-like caged xanthones with improved druglike properties and in vivo antitumor potency.

Wu Y, Hu M, Yang L, Li X, Bian J, Jiang F, Sun H, You Q, Zhang X.

Bioorg Med Chem Lett. 2015 Jun 15;25(12):2584-8. doi: 10.1016/j.bmcl.2015.04.031. Epub 2015 Apr 18.

PMID:
25958244
3.

[Progress in research of the structural optimization of natural product-like Garcinia caged xanthones].

Wang YY, Zhang XJ, Yang YR, Sun HP, You QD.

Yao Xue Xue Bao. 2014 Mar;49(3):293-302. Review. Chinese.

PMID:
24961098
4.

Caged Garcinia xanthones: development since 1937.

Han QB, Xu HX.

Curr Med Chem. 2009;16(28):3775-96. Review.

PMID:
19747141
5.

Synthesis and evaluation of caged Garcinia xanthones.

Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA.

Org Biomol Chem. 2007 Feb 7;5(3):494-500. Epub 2006 Dec 20.

PMID:
17252132
6.

Studies on chemical structure modification and structure-activity relationship of derivatives of gambogic acid at C(39).

Sun HP, Liu ZL, Xue X, Gao Y, Zhang L, Wang JX, Guo QL, You QD.

Chem Biodivers. 2012 Aug;9(8):1579-90. doi: 10.1002/cbdv.201100415.

PMID:
22899618
7.

Evaluation of the pharmacophoric motif of the caged Garcinia xanthones.

Chantarasriwong O, Cho WC, Batova A, Chavasiri W, Moore C, Rheingold AL, Theodorakis EA.

Org Biomol Chem. 2009 Dec 7;7(23):4886-94. doi: 10.1039/b913496d. Epub 2009 Sep 24.

8.

Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi.

Tao SJ, Guan SH, Wang W, Lu ZQ, Chen GT, Sha N, Yue QX, Liu X, Guo DA.

J Nat Prod. 2009 Jan;72(1):117-24. doi: 10.1021/np800460b.

PMID:
19072548
9.

A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones.

Elbel KM, Guizzunti G, Theodoraki MA, Xu J, Batova A, Dakanali M, Theodorakis EA.

Org Biomol Chem. 2013 May 28;11(20):3341-8. doi: 10.1039/c3ob40395e.

10.

Multidimensional optimization of promising antitumor xanthone derivatives.

Azevedo CM, Afonso CM, Sousa D, Lima RT, Vasconcelos MH, Pedro M, Barbosa J, CorrĂȘa AG, Reis S, Pinto MM.

Bioorg Med Chem. 2013 Jun 1;21(11):2941-59. doi: 10.1016/j.bmc.2013.03.079. Epub 2013 Apr 6.

PMID:
23623253
11.

Three new xanthones from the resin of Garcinia hanburyi.

Deng YX, Guo T, Shao ZY, Xie H, Pan SL.

Planta Med. 2013 Jun;79(9):792-6. doi: 10.1055/s-0032-1328537. Epub 2013 May 13.

PMID:
23670620
12.

Five novel prenylated xanthones from Resina Garciniae.

Feng F, Liu WY, Chen YS, Guo QL, You QD.

J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):735-41.

PMID:
17994391
13.

Synthesis and oral antitumor activity of tetrakis(carboxylato)platinum(IV) complexes.

Lee YA, Lee SS, Kim KM, Lee CO, Sohn YS.

J Med Chem. 2000 Apr 6;43(7):1409-12.

PMID:
10753477
14.

Synthesis and evaluation of novel aza-caged Garcinia xanthones.

Zhang X, Li X, Sun H, Jiang Z, Tao L, Gao Y, Guo Q, You Q.

Org Biomol Chem. 2012 Apr 28;10(16):3288-99. doi: 10.1039/c2ob07088j. Epub 2012 Mar 12.

PMID:
22407464
15.

Structure-activity relationship of Garcinia xanthones analogues: Potent Hsp90 inhibitors with cytotoxicity and antiangiogenesis activity.

Xu X, Wu Y, Hu M, Li X, Gu C, You Q, Zhang X.

Bioorg Med Chem. 2016 Oct 1;24(19):4626-4635. doi: 10.1016/j.bmc.2016.07.067. Epub 2016 Aug 1.

PMID:
27527413
16.

Synthesis and antitumor activity evaluation of a novel series of xanthone derivatives.

Guo N, Liu J, Qin L, Jiang D, You X, Lu K, Teng YO, Yu P.

J Asian Nat Prod Res. 2015;17(4):377-83. doi: 10.1080/10286020.2014.1003048. Epub 2015 Jan 28.

PMID:
25628155
17.

Synthesis and in vitro antitumor activities of xanthone derivatives containing 1,4-disubstituted-1,2,3-triazole moiety.

Zou Y, Zhao Q, Hu H, Hu L, Yu S, Xu M, Wu Q.

Arch Pharm Res. 2012 Dec;35(12):2093-104. doi: 10.1007/s12272-012-1206-4. Epub 2012 Dec 21.

PMID:
23263803
18.

Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi.

Han QB, Wang YL, Yang L, Tso TF, Qiao CF, Song JZ, Xu LJ, Chen SL, Yang DJ, Xu HX.

Chem Pharm Bull (Tokyo). 2006 Feb;54(2):265-7.

19.

Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols from Garcinia oblongifolia.

Huang SX, Feng C, Zhou Y, Xu G, Han QB, Qiao CF, Chang DC, Luo KQ, Xu HX.

J Nat Prod. 2009 Jan;72(1):130-5. doi: 10.1021/np800496c.

PMID:
19113969
20.

Bioassay-guided isolation of prenylated xanthones and polycyclic acylphloroglucinols from the leaves of Garcinia nujiangensis.

Xia ZX, Zhang DD, Liang S, Lao YZ, Zhang H, Tan HS, Chen SL, Wang XH, Xu HX.

J Nat Prod. 2012 Aug 24;75(8):1459-64. doi: 10.1021/np3003639. Epub 2012 Aug 7.

PMID:
22871217

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