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Items: 1 to 20 of 108

1.

BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.

Basso K, Schneider C, Shen Q, Holmes AB, Setty M, Leslie C, Dalla-Favera R.

J Exp Med. 2012 Dec 17;209(13):2455-65. doi: 10.1084/jem.20121387. Epub 2012 Nov 19.

2.

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein.

Lee CH, Melchers M, Wang H, Torrey TA, Slota R, Qi CF, Kim JY, Lugar P, Kong HJ, Farrington L, van der Zouwen B, Zhou JX, Lougaris V, Lipsky PE, Grammer AC, Morse HC 3rd.

J Exp Med. 2006 Jan 23;203(1):63-72. Epub 2005 Dec 27. Erratum in: J Exp Med. 2008 Jun 9;205(6):1507. J Exp Med. 2006 Feb 20;203(2):475.

3.

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Basso K, Saito M, Sumazin P, Margolin AA, Wang K, Lim WK, Kitagawa Y, Schneider C, Alvarez MJ, Califano A, Dalla-Favera R.

Blood. 2010 Feb 4;115(5):975-84. doi: 10.1182/blood-2009-06-227017. Epub 2009 Dec 3.

4.

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells.

Phan RT, Dalla-Favera R.

Nature. 2004 Dec 2;432(7017):635-9.

5.

BCL6 promoter interacts with far upstream sequences with greatly enhanced activating histone modifications in germinal center B cells.

Ramachandrareddy H, Bouska A, Shen Y, Ji M, Rizzino A, Chan WC, McKeithan TW.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11930-5. doi: 10.1073/pnas.1004962107. Epub 2010 Jun 14.

6.

Mechanisms of action of BCL6 during germinal center B cell development.

Huang C, Melnick A.

Sci China Life Sci. 2015 Dec;58(12):1226-32. doi: 10.1007/s11427-015-4919-z. Epub 2015 Nov 14. Review.

PMID:
26566802
7.

JunD/AP-1 and STAT3 are the major enhancer molecules for high Bcl6 expression in germinal center B cells.

Arguni E, Arima M, Tsuruoka N, Sakamoto A, Hatano M, Tokuhisa T.

Int Immunol. 2006 Jul;18(7):1079-89. Epub 2006 May 15.

PMID:
16702165
8.

p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression.

Zhang TT, Makondo KJ, Marshall AJ.

J Immunol. 2012 Apr 15;188(8):3700-8. doi: 10.4049/jimmunol.1103302. Epub 2012 Mar 14.

9.

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

Saito M, Novak U, Piovan E, Basso K, Sumazin P, Schneider C, Crespo M, Shen Q, Bhagat G, Califano A, Chadburn A, Pasqualucci L, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11294-9. doi: 10.1073/pnas.0903854106. Epub 2009 Jun 23.

10.

miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.

Sandhu SK, Volinia S, Costinean S, Galasso M, Neinast R, Santhanam R, Parthun MR, Perrotti D, Marcucci G, Garzon R, Croce CM.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20047-52. doi: 10.1073/pnas.1213764109. Epub 2012 Nov 19.

11.

Differential regulation of germinal center genes, BCL6 and SWAP-70, during the course of MAIDS.

Qi CF, Jessberger R, Torrey TA, Taddesse-Heath L, Ohta Y, Morse HC 3rd.

Mol Immunol. 1999 Oct-Nov;36(15-16):1043-53.

PMID:
10698307
12.

The BCL6 proto-oncogene: a leading role during germinal center development and lymphomagenesis.

Jardin F, Ruminy P, Bastard C, Tilly H.

Pathol Biol (Paris). 2007 Feb;55(1):73-83. Epub 2006 Jul 3. Review.

PMID:
16815642
13.

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

Guikema JE, Linehan EK, Esa N, Tsuchimoto D, Nakabeppu Y, Woodland RT, Schrader CE.

J Immunol. 2014 Jul 15;193(2):931-9. doi: 10.4049/jimmunol.1400002. Epub 2014 Jun 16.

14.

BCL6 controls the expression of the B7-1/CD80 costimulatory receptor in germinal center B cells.

Niu H, Cattoretti G, Dalla-Favera R.

J Exp Med. 2003 Jul 21;198(2):211-21. Epub 2003 Jul 14.

15.

BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Adv Immunol. 2010;105:193-210. doi: 10.1016/S0065-2776(10)05007-8. Review.

PMID:
20510734
16.

PU.1 can recruit BCL6 to DNA to repress gene expression in germinal center B cells.

Wei F, Zaprazna K, Wang J, Atchison ML.

Mol Cell Biol. 2009 Sep;29(17):4612-22. doi: 10.1128/MCB.00234-09. Epub 2009 Jun 29.

17.

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation.

Huang C, Geng H, Boss I, Wang L, Melnick A.

Blood. 2014 Feb 13;123(7):1012-20. doi: 10.1182/blood-2013-07-518605. Epub 2013 Nov 25.

18.

The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis.

Baron BW, Anastasi J, Thirman MJ, Furukawa Y, Fears S, Kim DC, Simone F, Birkenbach M, Montag A, Sadhu A, Zeleznik-Le N, McKeithan TW.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2860-5. Epub 2002 Feb 19.

19.

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.

Yoon J, Feng X, Kim YS, Shin DM, Hatzi K, Wang H, Morse HC 3rd.

J Biol Chem. 2014 Dec 5;289(49):34250-7. doi: 10.1074/jbc.M114.571182. Epub 2014 Oct 20.

20.

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells.

Phan RT, Saito M, Basso K, Niu H, Dalla-Favera R.

Nat Immunol. 2005 Oct;6(10):1054-60. Epub 2005 Sep 4.

PMID:
16142238

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