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Items: 1 to 20 of 140

1.

TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi.

Petnicki-Ocwieja T, Chung E, Acosta DI, Ramos LT, Shin OS, Ghosh S, Kobzik L, Li X, Hu LT.

Infect Immun. 2013 Feb;81(2):402-10. doi: 10.1128/IAI.00890-12. Epub 2012 Nov 19.

2.
3.

Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K.

Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, Hu LT.

J Immunol. 2009 Jul 1;183(1):491-8. doi: 10.4049/jimmunol.0900724.

4.

Campylobacter jejuni-induced activation of dendritic cells involves cooperative signaling through Toll-like receptor 4 (TLR4)-MyD88 and TLR4-TRIF axes.

Rathinam VA, Appledorn DM, Hoag KA, Amalfitano A, Mansfield LS.

Infect Immun. 2009 Jun;77(6):2499-507. doi: 10.1128/IAI.01562-08. Epub 2009 Mar 30.

5.

Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages.

Ruckdeschel K, Pfaffinger G, Haase R, Sing A, Weighardt H, Häcker G, Holzmann B, Heesemann J.

J Immunol. 2004 Sep 1;173(5):3320-8.

6.

Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction.

Shin OS, Isberg RR, Akira S, Uematsu S, Behera AK, Hu LT.

Infect Immun. 2008 Jun;76(6):2341-51. doi: 10.1128/IAI.01600-07. Epub 2008 Mar 31.

7.

A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.

Nilsen NJ, Vladimer GI, Stenvik J, Orning MP, Zeid-Kilani MV, Bugge M, Bergstroem B, Conlon J, Husebye H, Hise AG, Fitzgerald KA, Espevik T, Lien E.

J Biol Chem. 2015 Feb 6;290(6):3209-22. doi: 10.1074/jbc.M114.593426. Epub 2014 Dec 11.

8.

The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery.

Leichtle A, Hernandez M, Pak K, Webster NJ, Wasserman SI, Ryan AF.

BMC Immunol. 2009 Aug 5;10:45. doi: 10.1186/1471-2172-10-45.

9.

Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.

10.

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif.

Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, Anders HJ.

Am J Physiol Renal Physiol. 2009 Apr;296(4):F867-74. doi: 10.1152/ajprenal.90213.2008. Epub 2009 Jan 21.

11.

Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF.

Kolb JP, Casella CR, SenGupta S, Chilton PM, Mitchell TC.

Sci Signal. 2014 Nov 11;7(351):ra108. doi: 10.1126/scisignal.2005442.

12.

Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling.

Wang S, Schmaderer C, Kiss E, Schmidt C, Bonrouhi M, Porubsky S, Gretz N, Schaefer L, Kirschning CJ, Popovic ZV, Gröne HJ.

Dis Model Mech. 2010 Jan-Feb;3(1-2):92-103. doi: 10.1242/dmm.003533. Epub 2009 Dec 28.

13.

Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.

Chuffa LG, Fioruci-Fontanelli BA, Mendes LO, Ferreira Seiva FR, Martinez M, Fávaro WJ, Domeniconi RF, Pinheiro PF, Delazari Dos Santos L, Martinez FE.

BMC Cancer. 2015 Feb 6;15:34. doi: 10.1186/s12885-015-1032-4.

14.

Adaptor Protein-3-Mediated Trafficking of TLR2 Ligands Controls Specificity of Inflammatory Responses but Not Adaptor Complex Assembly.

Petnicki-Ocwieja T, Kern A, Killpack TL, Bunnell SC, Hu LT.

J Immunol. 2015 Nov 1;195(9):4331-40. doi: 10.4049/jimmunol.1501268. Epub 2015 Sep 30.

15.

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S.

Science. 2003 Aug 1;301(5633):640-3. Epub 2003 Jul 10.

16.

MyD88 plays a unique role in host defense but not arthritis development in Lyme disease.

Bolz DD, Sundsbak RS, Ma Y, Akira S, Kirschning CJ, Zachary JF, Weis JH, Weis JJ.

J Immunol. 2004 Aug 1;173(3):2003-10.

18.

MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands.

Zheng H, Heiderscheidt CA, Joo M, Gao X, Knezevic N, Mehta D, Sadikot RT.

Eur J Immunol. 2010 Jan;40(1):162-71. doi: 10.1002/eji.200839156.

19.

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.

Siednienko J, Halle A, Nagpal K, Golenbock DT, Miggin SM.

Eur J Immunol. 2010 Nov;40(11):3150-60. doi: 10.1002/eji.201040547. Epub 2010 Oct 19.

20.

Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria.

Parkunan SM, Randall CB, Coburn PS, Astley RA, Staats RL, Callegan MC.

Infect Immun. 2015 Oct;83(10):3926-36. doi: 10.1128/IAI.00502-15. Epub 2015 Jul 20.

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