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Items: 1 to 20 of 87

1.

Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge.

Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, Remling-Mulder L, Akkina R, Rossi JJ.

Mol Ther. 2013 Jan;21(1):192-200. doi: 10.1038/mt.2012.226. Epub 2012 Nov 20.

2.

Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition.

Zhou J, Shu Y, Guo P, Smith DD, Rossi JJ.

Methods. 2011 Jun;54(2):284-94. doi: 10.1016/j.ymeth.2010.12.039. Epub 2011 Jan 20.

3.

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells.

Zhou J, Swiderski P, Li H, Zhang J, Neff CP, Akkina R, Rossi JJ.

Nucleic Acids Res. 2009 May;37(9):3094-109. doi: 10.1093/nar/gkp185. Epub 2009 Mar 21.

4.

Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy.

Zhou J, Li H, Li S, Zaia J, Rossi JJ.

Mol Ther. 2008 Aug;16(8):1481-9. doi: 10.1038/mt.2008.92. Epub 2008 May 6.

5.

Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery.

Zhou J, Li H, Zhang J, Piotr S, Rossi J.

J Vis Exp. 2011 Jun 23;(52). pii: 2954. doi: 10.3791/2954.

6.

Aptamer-targeted RNAi for HIV-1 therapy.

Zhou J, Rossi JJ.

Methods Mol Biol. 2011;721:355-71. doi: 10.1007/978-1-61779-037-9_22.

PMID:
21431697
7.

An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.

Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R.

Sci Transl Med. 2011 Jan 19;3(66):66ra6. doi: 10.1126/scitranslmed.3001581.

8.

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.

Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ.

Mol Ther. 2011 Dec;19(12):2228-38. doi: 10.1038/mt.2011.207. Epub 2011 Sep 27.

9.

Aptamer-siRNA chimeras for HIV.

Takahashi M, Burnett JC, Rossi JJ.

Adv Exp Med Biol. 2015;848:211-34. doi: 10.1007/978-1-4939-2432-5_11. Review.

PMID:
25757623
10.

Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy.

Zhou J, Rossi J.

J Investig Med. 2014 Oct;62(7):914-9. doi: 10.1097/JIM.0000000000000103. Review.

11.

Therapeutic potential of aptamer-siRNA conjugates for treatment of HIV-1.

Zhou J, Rossi JJ.

BioDrugs. 2012 Dec 1;26(6):393-400. doi: 10.2165/11635350-000000000-00000. Review.

12.

Methods for assembling B-cell lymphoma specific and internalizing aptamer-siRNA nanoparticles via the sticky bridge.

Zhou J, Rossi JJ, Shum KT.

Methods Mol Biol. 2015;1297:169-85. doi: 10.1007/978-1-4939-2562-9_12.

PMID:
25896003
13.

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras.

McNamara JO 2nd, Andrechek ER, Wang Y, Viles KD, Rempel RE, Gilboa E, Sullenger BA, Giangrande PH.

Nat Biotechnol. 2006 Aug;24(8):1005-15. Epub 2006 Jun 25.

PMID:
16823371
14.

Intracellular delivery of RNA-based therapeutics using aptamers.

Thiel KW, Giangrande PH.

Ther Deliv. 2010 Dec;1(6):849-61. doi: 10.4155/tde.10.61. Review.

15.

Deep Sequencing Analyses of DsiRNAs Reveal the Influence of 3' Terminal Overhangs on Dicing Polarity, Strand Selectivity, and RNA Editing of siRNAs.

Zhou J, Song MS, Jacobi AM, Behlke MA, Wu X, Rossi JJ.

Mol Ther Nucleic Acids. 2012 Apr 3;1:e17. doi: 10.1038/mtna.2012.6.

16.

Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA.

Zhu Q, Shibata T, Kabashima T, Kai M.

Eur J Med Chem. 2012 Oct;56:396-9. doi: 10.1016/j.ejmech.2012.07.045. Epub 2012 Aug 3.

PMID:
22907035
17.

Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.

Wullner U, Neef I, Eller A, Kleines M, Tur MK, Barth S.

Curr Cancer Drug Targets. 2008 Nov;8(7):554-65.

PMID:
18991566
18.
19.

Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells.

Park WS, Hayafune M, Miyano-Kurosaki N, Takaku H.

Gene Ther. 2003 Nov;10(24):2046-50.

PMID:
14566364
20.

Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4.

Zhou N, Fang J, Mukhtar M, Acheampong E, Pomerantz RJ.

Gene Ther. 2004 Dec;11(23):1703-12.

PMID:
15306840

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