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Items: 1 to 20 of 373

1.

The critical role of mast cell-derived hypoxia-inducible factor-1α in human and mice melanoma growth.

Jeong HJ, Oh HA, Nam SY, Han NR, Kim YS, Kim JH, Lee SJ, Kim MH, Moon PD, Kim HM, Oh HA.

Int J Cancer. 2013 Jun 1;132(11):2492-501. doi: 10.1002/ijc.27937. Epub 2012 Dec 3.

2.

Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.

Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A.

Oncotarget. 2016 Feb 16;7(7):7816-28. doi: 10.18632/oncotarget.6868.

3.

Hypoxic stress simultaneously stimulates vascular endothelial growth factor via hypoxia-inducible factor-1α and inhibits stromal cell-derived factor-1 in human endometrial stromal cells.

Tsuzuki T, Okada H, Cho H, Tsuji S, Nishigaki A, Yasuda K, Kanzaki H.

Hum Reprod. 2012 Feb;27(2):523-30. doi: 10.1093/humrep/der405. Epub 2011 Nov 28.

PMID:
22128293
4.

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis.

Nam SY, Ko YS, Jung J, Yoon J, Kim YH, Choi YJ, Park JW, Chang MS, Kim WH, Lee BL.

Br J Cancer. 2011 Jan 4;104(1):166-74. doi: 10.1038/sj.bjc.6606020. Epub 2010 Nov 30.

5.

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

Gabellini C, De Luca T, Trisciuoglio D, Desideri M, Di Martile M, Passeri D, Candiloro A, Biffoni M, Rizzo MG, Orlandi A, Del Bufalo D.

Carcinogenesis. 2013 Nov;34(11):2558-67. doi: 10.1093/carcin/bgt242. Epub 2013 Jul 8.

PMID:
23836782
6.

Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis.

Roda JM, Sumner LA, Evans R, Phillips GS, Marsh CB, Eubank TD.

J Immunol. 2011 Aug 15;187(4):1970-6. doi: 10.4049/jimmunol.1100841. Epub 2011 Jul 15.

7.

Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis.

Chang CC, Lin MT, Lin BR, Jeng YM, Chen ST, Chu CY, Chen RJ, Chang KJ, Yang PC, Kuo ML.

J Natl Cancer Inst. 2006 Jul 19;98(14):984-95.

PMID:
16849681
8.

Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis.

Paradziej-Łukowicz J, Skwarska A, Peszyńska-Sularz G, Brillowska-Dąbrowska A, Konopa J.

Cancer Biol Ther. 2011 Oct 1;12(7):586-97. Epub 2011 Oct 1.

PMID:
21775820
9.

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).

De Francesco EM, Lappano R, Santolla MF, Marsico S, Caruso A, Maggiolini M.

Breast Cancer Res. 2013;15(4):R64.

10.

Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis.

Lee MN, Lee SN, Kim SH, Kim B, Jung BK, Seo JH, Park JH, Choi JH, Yim SH, Lee MR, Park JG, Yoo JY, Kim JH, Lee ST, Kim HM, Ryeom S, Kim KW, Oh GT.

J Natl Cancer Inst. 2010 Mar 17;102(6):426-42. doi: 10.1093/jnci/djq026. Epub 2010 Mar 1.

11.

The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor.

Spinella F, Caprara V, Cianfrocca R, Rosanò L, Di Castro V, Garrafa E, Natali PG, Bagnato A.

Carcinogenesis. 2014 Apr;35(4):840-8. doi: 10.1093/carcin/bgu018. Epub 2014 Jan 28.

12.

Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.

Stoeltzing O, McCarty MF, Wey JS, Fan F, Liu W, Belcheva A, Bucana CD, Semenza GL, Ellis LM.

J Natl Cancer Inst. 2004 Jun 16;96(12):946-56.

PMID:
15199114
13.

Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.

Pourgholami MH, Cai ZY, Badar S, Wangoo K, Poruchynsky MS, Morris DL.

BMC Cancer. 2010 Apr 15;10:143. doi: 10.1186/1471-2407-10-143.

14.

Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells.

Spinella F, Rosanò L, Di Castro V, Decandia S, Nicotra MR, Natali PG, Bagnato A.

Cancer Res. 2007 Feb 15;67(4):1725-34.

15.

Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.

Ji X, Wang H, Zhu J, Zhu L, Pan H, Li W, Zhou Y, Cong Z, Yan F, Chen S.

Int J Cancer. 2014 Aug 1;135(3):574-84. doi: 10.1002/ijc.28699. Epub 2014 Jan 10.

16.

Inhibition of proliferation, migration and tube formation of choroidal microvascular endothelial cells by targeting HIF-1alpha with short hairpin RNA-expressing plasmid DNA in human RPE cells in a coculture system.

Zhao W, Wang YS, Hui YN, Zhu J, Zhang P, Li X, Dou GR.

Graefes Arch Clin Exp Ophthalmol. 2008 Oct;246(10):1413-22. doi: 10.1007/s00417-008-0858-8. Epub 2008 Jun 4.

PMID:
18523795
17.

Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway.

Park JJ, Hwang SJ, Park JH, Lee HJ.

Cell Oncol (Dordr). 2015 Apr;38(2):111-8. doi: 10.1007/s13402-014-0216-2. Epub 2015 Jan 6.

PMID:
25561311
18.

HIF-1α is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer.

Miyake S, Kitajima Y, Nakamura J, Kai K, Yanagihara K, Tanaka T, Hiraki M, Miyazaki K, Noshiro H.

Int J Oncol. 2013 Nov;43(5):1431-40. doi: 10.3892/ijo.2013.2068. Epub 2013 Aug 21.

PMID:
23970191
19.

Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.

Kuwai T, Kitadai Y, Tanaka S, Onogawa S, Matsutani N, Kaio E, Ito M, Chayama K.

Int J Cancer. 2003 Jun 10;105(2):176-81.

20.

Mast cells can mediate vascular permeability through regulation of the PI3K-HIF-1alpha-VEGF axis.

Lee KS, Kim SR, Park SJ, Min KH, Lee KY, Choe YH, Park SY, Chai OH, Zhang X, Song CH, Lee YC.

Am J Respir Crit Care Med. 2008 Oct 15;178(8):787-97. doi: 10.1164/rccm.200801-008OC. Epub 2008 Jul 31.

PMID:
18669818

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