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Items: 1 to 20 of 166

1.

Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils.

Binger KJ, Ecroyd H, Yang S, Carver JA, Howlett GJ, Griffin MD.

FASEB J. 2013 Mar;27(3):1214-22. doi: 10.1096/fj.12-220657. Epub 2012 Nov 16.

PMID:
23159935
2.

AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin.

Raman B, Ban T, Sakai M, Pasta SY, Ramakrishna T, Naiki H, Goto Y, Rao ChM.

Biochem J. 2005 Dec 15;392(Pt 3):573-81.

3.

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.

Rekas A, Adda CG, Andrew Aquilina J, Barnham KJ, Sunde M, Galatis D, Williamson NA, Masters CL, Anders RF, Robinson CV, Cappai R, Carver JA.

J Mol Biol. 2004 Jul 23;340(5):1167-83.

PMID:
15236975
5.

Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins.

Meehan S, Knowles TP, Baldwin AJ, Smith JF, Squires AM, Clements P, Treweek TM, Ecroyd H, Tartaglia GG, Vendruscolo M, Macphee CE, Dobson CM, Carver JA.

J Mol Biol. 2007 Sep 14;372(2):470-84. Epub 2007 Jun 29.

PMID:
17662998
6.

αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide.

Dehle FC, Ecroyd H, Musgrave IF, Carver JA.

Cell Stress Chaperones. 2010 Nov;15(6):1013-26. doi: 10.1007/s12192-010-0212-z. Epub 2010 Jul 15.

7.

Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.

Shammas SL, Waudby CA, Wang S, Buell AK, Knowles TP, Ecroyd H, Welland ME, Carver JA, Dobson CM, Meehan S.

Biophys J. 2011 Oct 5;101(7):1681-9. doi: 10.1016/j.bpj.2011.07.056.

8.

Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways.

Griffin MD, Mok ML, Wilson LM, Pham CL, Waddington LJ, Perugini MA, Howlett GJ.

J Mol Biol. 2008 Jan 4;375(1):240-56. Epub 2007 Oct 22.

PMID:
18005990
9.

Methionine oxidation inhibits assembly and promotes disassembly of apolipoprotein C-II amyloid fibrils.

Binger KJ, Griffin MD, Howlett GJ.

Biochemistry. 2008 Sep 23;47(38):10208-17. doi: 10.1021/bi8009339. Epub 2008 Aug 26.

PMID:
18729385
10.

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

Wilson LM, Mok YF, Binger KJ, Griffin MD, Mertens HD, Lin F, Wade JD, Gooley PR, Howlett GJ.

J Mol Biol. 2007 Mar 9;366(5):1639-51. Epub 2006 Dec 21.

PMID:
17217959
11.

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

Mao Y, Zlatic CO, Griffin MD, Howlett GJ, Todorova N, Yarovsky I, Gooley PR.

Biochemistry. 2015 Aug 11;54(31):4805-14. doi: 10.1021/acs.biochem.5b00535. Epub 2015 Aug 3.

PMID:
26196342
12.

Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species.

Rekas A, Jankova L, Thorn DC, Cappai R, Carver JA.

FEBS J. 2007 Dec;274(24):6290-304. Epub 2007 Nov 12.

13.

Structural and functional aspects of hetero-oligomers formed by the small heat shock proteins αB-crystallin and HSP27.

Aquilina JA, Shrestha S, Morris AM, Ecroyd H.

J Biol Chem. 2013 May 10;288(19):13602-9. doi: 10.1074/jbc.M112.443812. Epub 2013 Mar 26.

14.

Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E.

Gunzburg MJ, Perugini MA, Howlett GJ.

J Biol Chem. 2007 Dec 7;282(49):35831-41. Epub 2007 Oct 4.

15.

Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.

Zlatic CO, Mao Y, Ryan TM, Mok YF, Roberts BR, Howlett GJ, Griffin MD.

Biochemistry. 2015 Jun 23;54(24):3831-8. doi: 10.1021/acs.biochem.5b00399. Epub 2015 Jun 12.

PMID:
26021642
16.

The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II.

Hatters DM, Lindner RA, Carver JA, Howlett GJ.

J Biol Chem. 2001 Sep 7;276(36):33755-61. Epub 2001 Jul 10.

17.

Shear flow induced changes in apolipoprotein C-II conformation and amyloid fibril formation.

Teoh CL, Bekard IB, Asimakis P, Griffin MD, Ryan TM, Dunstan DE, Howlett GJ.

Biochemistry. 2011 May 17;50(19):4046-57. doi: 10.1021/bi2002482. Epub 2011 Apr 22.

PMID:
21476595
18.

Crystallin proteins and amyloid fibrils.

Ecroyd H, Carver JA.

Cell Mol Life Sci. 2009 Jan;66(1):62-81. doi: 10.1007/s00018-008-8327-4. Review.

PMID:
18810322
19.

Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II.

Ryan TM, Howlett GJ, Bailey MF.

J Biol Chem. 2008 Dec 12;283(50):35118-28. doi: 10.1074/jbc.M804004200. Epub 2008 Oct 13.

20.

Oxidized cholesterol metabolites found in human atherosclerotic lesions promote apolipoprotein C-II amyloid fibril formation.

Stewart CR, Wilson LM, Zhang Q, Pham CL, Waddington LJ, Staples MK, Stapleton D, Kelly JW, Howlett GJ.

Biochemistry. 2007 May 8;46(18):5552-61. Epub 2007 Apr 13.

PMID:
17429947

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