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Items: 1 to 20 of 55

1.

Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype.

Singh V, Jamwal S, Jain R, Verma P, Gokhale R, Rao KV.

Cell Host Microbe. 2012 Nov 15;12(5):669-81. doi: 10.1016/j.chom.2012.09.012.

2.

M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation.

Singh V, Kaur C, Chaudhary VK, Rao KV, Chatterjee S.

Sci Rep. 2015 Aug 7;5:12906. doi: 10.1038/srep12906.

3.

Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response.

Singh A, Crossman DK, Mai D, Guidry L, Voskuil MI, Renfrow MB, Steyn AJ.

PLoS Pathog. 2009 Aug;5(8):e1000545. doi: 10.1371/journal.ppat.1000545. Epub 2009 Aug 14.

4.

The CFP10/ESAT6 complex of Mycobacterium tuberculosis may function as a regulator of macrophage cell death at different stages of tuberculosis infection.

Guo S, Xue R, Li Y, Wang SM, Ren L, Xu JJ.

Med Hypotheses. 2012 Mar;78(3):389-92. doi: 10.1016/j.mehy.2011.11.022. Epub 2011 Dec 21.

PMID:
22192908
6.

Attenuated Listeria monocytogenes, a Mycobacterium tuberculosis ESAT-6 antigen expression and delivery vector for inducing an immune response.

Yin Y, Tian D, Jia Y, Gao Y, Fu H, Niu Z, Sun L, Jiao X.

Res Microbiol. 2012 Sep-Oct;163(8):540-9. doi: 10.1016/j.resmic.2012.07.008. Epub 2012 Jul 23.

PMID:
22835946
7.

Endoplasmic reticulum stress response is involved in Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis.

Choi HH, Shin DM, Kang G, Kim KH, Park JB, Hur GM, Lee HM, Lim YJ, Park JK, Jo EK, Song CH.

FEBS Lett. 2010 Jun 3;584(11):2445-54. doi: 10.1016/j.febslet.2010.04.050. Epub 2010 Apr 21.

8.

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase.

McKinney JD, Höner zu Bentrup K, Muñoz-Elías EJ, Miczak A, Chen B, Chan WT, Swenson D, Sacchettini JC, Jacobs WR Jr, Russell DG.

Nature. 2000 Aug 17;406(6797):735-8.

PMID:
10963599
9.

Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages.

Daniel J, Maamar H, Deb C, Sirakova TD, Kolattukudy PE.

PLoS Pathog. 2011 Jun;7(6):e1002093. doi: 10.1371/journal.ppat.1002093. Epub 2011 Jun 23.

10.

A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion.

Gao LY, Guo S, McLaughlin B, Morisaki H, Engel JN, Brown EJ.

Mol Microbiol. 2004 Sep;53(6):1677-93.

11.

Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages.

Daim S, Kawamura I, Tsuchiya K, Hara H, Kurenuma T, Shen Y, Dewamitta SR, Sakai S, Nomura T, Qu H, Mitsuyama M.

J Med Microbiol. 2011 May;60(Pt 5):582-91. doi: 10.1099/jmm.0.026047-0. Epub 2011 Jan 13.

PMID:
21233299
12.

Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.

Means TK, Jones BW, Schromm AB, Shurtleff BA, Smith JA, Keane J, Golenbock DT, Vogel SN, Fenton MJ.

J Immunol. 2001 Mar 15;166(6):4074-82.

13.

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis.

Danelishvili L, Yamazaki Y, Selker J, Bermudez LE.

PLoS One. 2010 May 4;5(5):e10474. doi: 10.1371/journal.pone.0010474.

14.

Mycobacterium tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival.

Mahajan S, Dkhar HK, Chandra V, Dave S, Nanduri R, Janmeja AK, Agrewala JN, Gupta P.

J Immunol. 2012 Jun 1;188(11):5593-603. doi: 10.4049/jimmunol.1103038. Epub 2012 Apr 27.

15.
16.

The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response.

Kurtz S, McKinnon KP, Runge MS, Ting JP, Braunstein M.

Infect Immun. 2006 Dec;74(12):6855-64. Epub 2006 Oct 9.

17.
18.

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis.

Iantomasi R, Sali M, Cascioferro A, Palucci I, Zumbo A, Soldini S, Rocca S, Greco E, Maulucci G, De Spirito M, Fraziano M, Fadda G, Manganelli R, Delogu G.

Cell Microbiol. 2012 Mar;14(3):356-67. doi: 10.1111/j.1462-5822.2011.01721.x. Epub 2011 Dec 13.

PMID:
22050772
20.

Chewing the fat: lipid metabolism and homeostasis during M. tuberculosis infection.

Lovewell RR, Sassetti CM, VanderVen BC.

Curr Opin Microbiol. 2016 Feb;29:30-6. doi: 10.1016/j.mib.2015.10.002. Epub 2015 Nov 3. Review.

PMID:
26544033

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