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Items: 1 to 20 of 104

1.

Nicotinamide mononucleotide adenylyltransferase maintains active zone structure by stabilizing Bruchpilot.

Zang S, Ali YO, Ruan K, Zhai RG.

EMBO Rep. 2013 Jan;14(1):87-94. doi: 10.1038/embor.2012.181. Epub 2012 Nov 16.

2.

Chaperoning the synapse--NMNAT protects Bruchpilot from crashing.

Lauwers E, Verstreken P.

EMBO Rep. 2013 Jan;14(1):5-6. doi: 10.1038/embor.2012.193. Epub 2012 Nov 30. No abstract available.

3.

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity.

Zhai RG, Cao Y, Hiesinger PR, Zhou Y, Mehta SQ, Schulze KL, Verstreken P, Bellen HJ.

PLoS Biol. 2006 Nov;4(12):e416.

4.

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ.

Nature. 2008 Apr 17;452(7189):887-91. doi: 10.1038/nature06721. Epub 2008 Mar 16.

5.

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria.

Kitay BM, McCormack R, Wang Y, Tsoulfas P, Zhai RG.

Hum Mol Genet. 2013 Apr 15;22(8):1601-14. doi: 10.1093/hmg/ddt009. Epub 2013 Jan 11.

6.

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway.

Ali YO, McCormack R, Darr A, Zhai RG.

J Biol Chem. 2011 May 27;286(21):19089-99. doi: 10.1074/jbc.M111.219295. Epub 2011 Apr 8.

7.

Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress.

Ruan K, Zhu Y, Li C, Brazill JM, Zhai RG.

Nat Commun. 2015 Nov 30;6:10057. doi: 10.1038/ncomms10057.

8.

Nmnat exerts neuroprotective effects in dendrites and axons.

Wen Y, Parrish JZ, He R, Zhai RG, Kim MD.

Mol Cell Neurosci. 2011 Sep;48(1):1-8. doi: 10.1016/j.mcn.2011.05.002. Epub 2011 May 9.

9.

Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila.

Wagh DA, Rasse TM, Asan E, Hofbauer A, Schwenkert I, Dürrbeck H, Buchner S, Dabauvalle MC, Schmidt M, Qin G, Wichmann C, Kittel R, Sigrist SJ, Buchner E.

Neuron. 2006 Mar 16;49(6):833-44. Erratum in: Neuron. 2006 Jul 20;51(2):275.

10.

Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration.

Chen L, Nye DM, Stone MC, Weiner AT, Gheres KW, Xiong X, Collins CA, Rolls MM.

PLoS Genet. 2016 Dec 6;12(12):e1006503. doi: 10.1371/journal.pgen.1006503. eCollection 2016 Dec.

11.

Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.

Nieratschker V, Schubert A, Jauch M, Bock N, Bucher D, Dippacher S, Krohne G, Asan E, Buchner S, Buchner E.

PLoS Genet. 2009 Oct;5(10):e1000700. doi: 10.1371/journal.pgen.1000700. Epub 2009 Oct 23.

12.

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein.

Xiong X, Hao Y, Sun K, Li J, Li X, Mishra B, Soppina P, Wu C, Hume RI, Collins CA.

PLoS Biol. 2012;10(12):e1001440. doi: 10.1371/journal.pbio.1001440. Epub 2012 Dec 4.

13.

A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity.

Fang Y, Soares L, Teng X, Geary M, Bonini NM.

Curr Biol. 2012 Apr 10;22(7):590-5. doi: 10.1016/j.cub.2012.01.065. Epub 2012 Mar 15.

14.

NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.

Ali YO, Ruan K, Zhai RG.

Hum Mol Genet. 2012 Jan 15;21(2):237-50. doi: 10.1093/hmg/ddr449. Epub 2011 Sep 30.

15.

CK2α regulates the transcription of BRP in Drosophila.

Wairkar YP, Trivedi D, Natarajan R, Barnes K, Dolores L, Cho P.

Dev Biol. 2013 Dec 1;384(1):53-64. doi: 10.1016/j.ydbio.2013.09.025. Epub 2013 Sep 27.

16.

The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target.

Pan LZ, Ahn DG, Sharif T, Clements D, Gujar SA, Lee PW.

Cell Cycle. 2014;13(6):1041-8. doi: 10.4161/cc.28128. Epub 2014 Feb 7.

17.

PP2A and GSK-3beta act antagonistically to regulate active zone development.

Viquez NM, Füger P, Valakh V, Daniels RW, Rasse TM, DiAntonio A.

J Neurosci. 2009 Sep 16;29(37):11484-94. doi: 10.1523/JNEUROSCI.5584-08.2009.

18.

Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN.

Werner E, Ziegler M, Lerner F, Schweiger M, Heinemann U.

FEBS Lett. 2002 Apr 10;516(1-3):239-44. Erratum in: FEBS Lett 2002 Jul 17;523(1-3):254-5.

19.
20.

S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development.

Cheng L, Locke C, Davis GW.

J Cell Biol. 2011 Sep 19;194(6):921-35. doi: 10.1083/jcb.201101042.

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