Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 271

1.

Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes.

Burke DG, Rahim AA, Waddington SN, Karlsson S, Enquist I, Bhatia K, Mehta A, Vellodi A, Heales S.

J Inherit Metab Dis. 2013 Sep;36(5):869-72. doi: 10.1007/s10545-012-9561-3. Epub 2012 Nov 15. Erratum in: J Inherit Metab Dis. 2013 Nov;36(6):1089.

PMID:
23151684
2.

Beta-glucosidase 1 (GBA1) is a second bile acid β-glucosidase in addition to β-glucosidase 2 (GBA2). Study in β-glucosidase deficient mice and humans.

Harzer K, Blech-Hermoni Y, Goldin E, Felderhoff-Mueser U, Igney C, Sidransky E, Yildiz Y.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):308-12. doi: 10.1016/j.bbrc.2012.05.117. Epub 2012 May 30.

3.
4.

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2.

Boot RG, Verhoek M, Donker-Koopman W, Strijland A, van Marle J, Overkleeft HS, Wennekes T, Aerts JM.

J Biol Chem. 2007 Jan 12;282(2):1305-12. Epub 2006 Nov 14.

5.

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease.

Yildiz Y, Hoffmann P, Vom Dahl S, Breiden B, Sandhoff R, Niederau C, Horwitz M, Karlsson S, Filocamo M, Elstein D, Beck M, Sandhoff K, Mengel E, Gonzalez MC, Nöthen MM, Sidransky E, Zimran A, Mattheisen M.

Orphanet J Rare Dis. 2013 Sep 26;8:151. doi: 10.1186/1750-1172-8-151.

6.

Cholesterol glucosylation is catalyzed by transglucosylation reaction of β-glucosidase 1.

Akiyama H, Kobayashi S, Hirabayashi Y, Murakami-Murofushi K.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):838-43. doi: 10.1016/j.bbrc.2013.10.145. Epub 2013 Nov 6.

7.

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D.

J Biol Chem. 2017 Apr 14;292(15):6177-6189. doi: 10.1074/jbc.M116.762831. Epub 2017 Mar 3.

PMID:
28258214
8.

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes.

Herrera Moro Chao D, Kallemeijn WW, Marques AR, Orre M, Ottenhoff R, van Roomen C, Foppen E, Renner MC, Moeton M, van Eijk M, Boot RG, Kamphuis W, Hol EM, Aten J, Overkleeft HS, Kalsbeek A, Aerts JM.

PLoS One. 2015 Sep 29;10(9):e0138107. doi: 10.1371/journal.pone.0138107. eCollection 2015.

9.

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

Marques AR, Aten J, Ottenhoff R, van Roomen CP, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, De Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JM.

PLoS One. 2015 Aug 14;10(8):e0135889. doi: 10.1371/journal.pone.0135889. eCollection 2015.

10.

Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies.

Sardi SP, Clarke J, Viel C, Chan M, Tamsett TJ, Treleaven CM, Bu J, Sweet L, Passini MA, Dodge JC, Yu WH, Sidman RL, Cheng SH, Shihabuddin LS.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3537-42. doi: 10.1073/pnas.1220464110. Epub 2013 Jan 7.

12.

Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage.

Mizukami H, Mi Y, Wada R, Kono M, Yamashita T, Liu Y, Werth N, Sandhoff R, Sandhoff K, Proia RL.

J Clin Invest. 2002 May;109(9):1215-21.

13.

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.

Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L.

J Neurosci. 2016 Nov 16;36(46):11654-11670.

14.

The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi.

Körschen HG, Yildiz Y, Raju DN, Schonauer S, Bönigk W, Jansen V, Kremmer E, Kaupp UB, Wachten D.

J Biol Chem. 2013 Feb 1;288(5):3381-93. doi: 10.1074/jbc.M112.414714. Epub 2012 Dec 17.

15.

An evolutionary and structure-based docking model for glucocerebrosidase-saposin C and glucocerebrosidase-substrate interactions - relevance for Gaucher disease.

Atrian S, López-Viñas E, Gómez-Puertas P, Chabás A, Vilageliu L, Grinberg D.

Proteins. 2008 Feb 15;70(3):882-91.

PMID:
17803231
16.

Substrate compositional variation with tissue/region and Gba1 mutations in mouse models--implications for Gaucher disease.

Sun Y, Zhang W, Xu YH, Quinn B, Dasgupta N, Liou B, Setchell KD, Grabowski GA.

PLoS One. 2013;8(3):e57560. doi: 10.1371/journal.pone.0057560. Epub 2013 Mar 8.

17.

Cell surface associated glycohydrolases in normal and Gaucher disease fibroblasts.

Aureli M, Bassi R, Loberto N, Regis S, Prinetti A, Chigorno V, Aerts JM, Boot RG, Filocamo M, Sonnino S.

J Inherit Metab Dis. 2012 Nov;35(6):1081-91. doi: 10.1007/s10545-012-9478-x. Epub 2012 Apr 19.

PMID:
22526844
18.

Glucocerebrosidase enzyme activity in GBA mutation Parkinson's disease.

Ortega RA, Torres PA, Swan M, Nichols W, Boschung S, Raymond D, Barrett MJ, Johannes BA, Severt L, Shanker V, Hunt AL, Bressman S, Pastores GM, Saunders-Pullman R.

J Clin Neurosci. 2016 Jun;28:185-6. doi: 10.1016/j.jocn.2015.12.004. Epub 2016 Feb 5.

19.

Leukocyte beta-glucosidase in homozygotes and heterozygotes for Gaucher disease.

Raghavan SS, Topol J, Kolodny EH.

Am J Hum Genet. 1980 Mar;32(2):158-73.

20.

Knock-out of β-glucosidase 2 has no influence on dextran sulfate sodium-induced colitis.

Scharl M, Leucht K, Frey-Wagner I, Zeitz J, Hausmann M, Fischbeck A, Liebisch G, Kellermeier S, Pesch T, Arikkat J, Schmitz G, Fried M, Yildiz Y, Rogler G.

Digestion. 2011;84(2):156-67. doi: 10.1159/000327380. Epub 2011 May 12.

Supplemental Content

Support Center