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Items: 1 to 20 of 113

1.

Perturbations in the HDL metabolic pathway predispose to the development of osteoarthritis in mice following long-term exposure to western-type diet.

Triantaphyllidou IE, Kalyvioti E, Karavia E, Lilis I, Kypreos KE, Papachristou DJ.

Osteoarthritis Cartilage. 2013 Feb;21(2):322-30. doi: 10.1016/j.joca.2012.11.003. Epub 2012 Nov 11.

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Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

Béaslas O, Metso J, Nissilä E, Laurila PP, Kaiharju E, Batchu KC, Kaipiainen L, Mäyränpää MI, Yan D, Gylling H, Jauhiainen M, Olkkonen VM.

PLoS One. 2013;8(3):e58856. doi: 10.1371/journal.pone.0058856. Epub 2013 Mar 15.

5.

LCAT can rescue the abnormal phenotype produced by the natural ApoA-I mutations (Leu141Arg)Pisa and (Leu159Arg)FIN.

Koukos G, Chroni A, Duka A, Kardassis D, Zannis VI.

Biochemistry. 2007 Sep 18;46(37):10713-21. Epub 2007 Aug 21.

PMID:
17711302
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7.

The Effect of Natural LCAT Mutations on the Biogenesis of HDL.

Fotakis P, Kuivenhoven JA, Dafnis E, Kardassis D, Zannis VI.

Biochemistry. 2015 Jun 2;54(21):3348-59. doi: 10.1021/acs.biochem.5b00180. Epub 2015 May 22.

PMID:
25948084
8.

Functional lecithin:cholesterol acyltransferase deficiency and high density lipoprotein deficiency in transgenic mice overexpressing human apolipoprotein A-II.

Marzal-Casacuberta A, Blanco-Vaca F, Ishida BY, Julve-Gil J, Shen J, Calvet-Márquez S, González-Sastre F, Chan L.

J Biol Chem. 1996 Mar 22;271(12):6720-8.

9.

The role of lecithin:cholesterol acyltransferase in the modulation of cardiometabolic risks - a clinical update and emerging insights from animal models.

Ng DS.

Biochim Biophys Acta. 2012 Apr;1821(4):654-9. doi: 10.1016/j.bbalip.2011.12.012. Epub 2012 Jan 12. Review.

PMID:
22326749
10.
11.

Markedly accelerated catabolism of apolipoprotein A-II (ApoA-II) and high density lipoproteins containing ApoA-II in classic lecithin: cholesterol acyltransferase deficiency and fish-eye disease.

Rader DJ, Ikewaki K, Duverger N, Schmidt H, Pritchard H, Frohlich J, Clerc M, Dumon MF, Fairwell T, Zech L, et al.

J Clin Invest. 1994 Jan;93(1):321-30.

12.

Site-directed mutagenesis and structure-function analysis of the human apolipoprotein A-I. Relation between lecithin-cholesterol acyltransferase activation and lipid binding.

Minnich A, Collet X, Roghani A, Cladaras C, Hamilton RL, Fielding CJ, Zannis VI.

J Biol Chem. 1992 Aug 15;267(23):16553-60.

13.

Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits: LDL metabolism and HDL metabolism are affected in a gene dose-dependent manner.

Brousseau ME, Santamarina-Fojo S, Vaisman BL, Applebaum-Bowden D, Bérard AM, Talley GD, Brewer HB Jr, Hoeg JM.

J Lipid Res. 1997 Dec;38(12):2537-47.

14.

Effect of probucol in lecithin-cholesterol acyltransferase-deficient mice: inhibition of 2 independent cellular cholesterol-releasing pathways in vivo.

Tomimoto S, Tsujita M, Okazaki M, Usui S, Tada T, Fukutomi T, Ito S, Itoh M, Yokoyama S.

Arterioscler Thromb Vasc Biol. 2001 Mar;21(3):394-400.

15.

Lipoprotein X Causes Renal Disease in LCAT Deficiency.

Ossoli A, Neufeld EB, Thacker SG, Vaisman B, Pryor M, Freeman LA, Brantner CA, Baranova I, Francone NO, Demosky SJ Jr, Vitali C, Locatelli M, Abbate M, Zoja C, Franceschini G, Calabresi L, Remaley AT.

PLoS One. 2016 Feb 26;11(2):e0150083. doi: 10.1371/journal.pone.0150083. eCollection 2016.

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18.

Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations.

Holleboom AG, Daniil G, Fu X, Zhang R, Hovingh GK, Schimmel AW, Kastelein JJ, Stroes ES, Witztum JL, Hutten BA, Tsimikas S, Hazen SL, Chroni A, Kuivenhoven JA.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3066-75. doi: 10.1161/ATVBAHA.112.255711. Epub 2012 Sep 27.

19.

Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.

Mertens A, Verhamme P, Bielicki JK, Phillips MC, Quarck R, Verreth W, Stengel D, Ninio E, Navab M, Mackness B, Mackness M, Holvoet P.

Circulation. 2003 Apr 1;107(12):1640-6. Epub 2003 Mar 24.

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