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Items: 1 to 20 of 195

1.

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles.

Peng W, Świtalska M, Wang L, Mei ZW, Edazawa Y, Pang CQ, El-Tantawy El-Sayed I, Wietrzyk J, Inokuchi T.

Eur J Med Chem. 2012 Dec;58:441-51. doi: 10.1016/j.ejmech.2012.10.023. Epub 2012 Oct 24.

PMID:
23151321
2.

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.

Wang L, Switalska M, Mei ZW, Lu WJ, Takahara Y, Feng XW, El-Sayed Iel-T, Wietrzyk J, Inokuchi T.

Bioorg Med Chem. 2012 Aug 1;20(15):4820-9. doi: 10.1016/j.bmc.2012.05.054. Epub 2012 Jun 12.

PMID:
22748378
3.

New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors.

Luniewski W, Wietrzyk J, Godlewska J, Switalska M, Piskozub M, Peczynska-Czoch W, Kaczmarek L.

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6103-7. doi: 10.1016/j.bmcl.2012.08.032. Epub 2012 Aug 15.

PMID:
22944121
4.

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.

Sassatelli M, Bouchikhi F, Messaoudi S, Anizon F, Debiton E, Barthomeuf C, Prudhomme M, Moreau P.

Eur J Med Chem. 2006 Jan;41(1):88-100. Epub 2005 Dec 5.

PMID:
16330129
5.

Searching for new derivatives of neocryptolepine: synthesis, antiproliferative, antimicrobial and antifungal activities.

Sidoryk K, Jaromin A, Edward JA, Świtalska M, Stefańska J, Cmoch P, Zagrodzka J, Szczepek W, Peczyńska-Czoch W, Wietrzyk J, Kozubek A, Zarnowski R, Andes DR, Kaczmarek Ł.

Eur J Med Chem. 2014 May 6;78:304-13. doi: 10.1016/j.ejmech.2014.03.060. Epub 2014 Mar 20.

PMID:
24686017
6.

Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines.

Wang N, Świtalska M, Wu MY, Imai K, Ngoc TA, Pang CQ, Wang L, Wietrzyk J, Inokuchi T.

Eur J Med Chem. 2014 May 6;78:314-23. doi: 10.1016/j.ejmech.2014.03.038. Epub 2014 Mar 19.

PMID:
24686018
7.

Pim kinase inhibitory and antiproliferative activity of a novel series of meridianin C derivatives.

More KN, Jang HW, Hong VS, Lee J.

Bioorg Med Chem Lett. 2014 Jun 1;24(11):2424-8. doi: 10.1016/j.bmcl.2014.04.035. Epub 2014 Apr 16.

PMID:
24775304
8.

Synthesis and biological evaluation of 2-indolinone derivatives as potential antitumor agents.

Zou H, Zhang L, Ouyang J, Giulianotti MA, Yu Y.

Eur J Med Chem. 2011 Dec;46(12):5970-7. doi: 10.1016/j.ejmech.2011.10.009. Epub 2011 Oct 13.

PMID:
22019188
9.

Synthesis and primary cytotoxicity evaluation of arylmethylenenaphthofuranones derivatives.

Lardic M, Patry C, Duflos M, Guillon J, Massip S, Cruzalegui F, Edmonds T, Giraudet S, Marini L, Leonce S.

J Enzyme Inhib Med Chem. 2006 Jun;21(3):313-25.

PMID:
16918079
10.

Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.

Perchellet JP, Waters AM, Perchellet EM, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Chandrasoma N, Buszek KR.

Anticancer Res. 2012 Nov;32(11):4671-84.

11.

Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.

Bouchikhi F, Anizon F, Moreau P.

Eur J Med Chem. 2009 Jun;44(6):2705-10. doi: 10.1016/j.ejmech.2009.01.027. Epub 2009 Feb 5.

PMID:
19232788
12.

Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities.

Sabry NM, Mohamed HM, Khattab ES, Motlaq SS, El-Agrody AM.

Eur J Med Chem. 2011 Feb;46(2):765-72. doi: 10.1016/j.ejmech.2010.12.015. Epub 2010 Dec 21.

PMID:
21216502
13.

Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents.

Pierce LT, Cahill MM, Winfield HJ, McCarthy FO.

Eur J Med Chem. 2012 Oct;56:292-300. doi: 10.1016/j.ejmech.2012.08.002. Epub 2012 Aug 10.

PMID:
22910137
14.

Synthesis and in vitro cytotoxic evaluation of N-substituted benzo[5,6]cycloheptal[b]indoles.

Joseph B, Alagille D, Mérour JY, Léonce S.

Chem Pharm Bull (Tokyo). 2000 Dec;48(12):1872-6.

PMID:
11145134
15.

Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.

Bouchikhi F, Anizon F, Moreau P.

Eur J Med Chem. 2008 Apr;43(4):755-62. Epub 2007 Jun 3.

PMID:
17628214
16.

Synthesis and antiproliferative activity of the ring system [1,2]oxazolo[4,5-g]indole.

Barraja P, Caracausi L, Diana P, Spanò V, Montalbano A, Carbone A, Parrino B, Cirrincione G.

ChemMedChem. 2012 Nov;7(11):1901-4. doi: 10.1002/cmdc.201200296. Epub 2012 Aug 22.

PMID:
22915307
17.

Design, synthesis and antiproliferative activity of a novel class of indole-2-carboxylate derivatives.

Ji XY, Xue ST, Zhan YC, Shen JJ, Wu LT, Jin J, Wang Z, Li ZR.

Eur J Med Chem. 2014 Aug 18;83:409-18. doi: 10.1016/j.ejmech.2014.05.043. Epub 2014 May 15.

PMID:
24996136
18.

"On water" expedient synthesis of 3-indolyl-3-hydroxy oxindole derivatives and their anticancer activity in vitro.

Sai Prathima P, Rajesh P, Venkateswara Rao J, Sai Kailash U, Sridhar B, Mohan Rao M.

Eur J Med Chem. 2014 Sep 12;84:155-9. doi: 10.1016/j.ejmech.2014.07.004. Epub 2014 Jul 7.

PMID:
25016373
19.

Isoindolo[2,1-c]benzo[1,2,4]triazines: a new ring system with antiproliferative activity.

Diana P, Martorana A, Barraja P, Lauria A, Montalbano A, Almerico AM, Dattolo G, Cirrincione G.

Bioorg Med Chem. 2007 Jan 1;15(1):343-9. Epub 2006 Sep 29.

PMID:
17064918
20.

Synthesis and evaluation of indole-containing 3,5-diarylisoxazoles as potential pro-apoptotic antitumour agents.

Md Tohid SF, Ziedan NI, Stefanelli F, Fogli S, Westwell AD.

Eur J Med Chem. 2012 Oct;56:263-70. doi: 10.1016/j.ejmech.2012.08.009. Epub 2012 Aug 14.

PMID:
22955095
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