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Items: 1 to 20 of 128

1.

Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice.

Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA.

Protein Cell. 2013 Mar;4(3):231-42. doi: 10.1007/s13238-012-2098-2. Epub 2012 Nov 12. Erratum in: Protein Cell. 2013 Aug;4(8):641.

2.

Overexpression of nestin and vimentin in ependymal cells in hydrocephalus.

Takano T, Rutka JT, Becker LE.

Acta Neuropathol. 1996 Jul;92(1):90-7.

PMID:
8811130
3.

Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology.

Jain N, Lim LW, Tan WT, George B, Makeyev E, Thanabalu T.

Exp Neurol. 2014 Apr;254:29-40. doi: 10.1016/j.expneurol.2014.01.011. Epub 2014 Jan 23.

PMID:
24462670
4.

Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects.

Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X.

Dev Biol. 2013 Nov 15;383(2):239-52. doi: 10.1016/j.ydbio.2013.09.013. Epub 2013 Sep 18.

5.

Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of hyh mutant mice developing congenital hydrocephalus.

Wagner C, Batiz LF, Rodríguez S, Jiménez AJ, Páez P, Tomé M, Pérez-Fígares JM, Rodríguez EM.

J Neuropathol Exp Neurol. 2003 Oct;62(10):1019-40.

PMID:
14575238
6.

Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex.

Yokota Y, Eom TY, Stanco A, Kim WY, Rao S, Snider WD, Anton ES.

Development. 2010 Dec;137(23):4101-10. doi: 10.1242/dev.048637.

7.

The generation of the endothelial specific cdc42-deficient mice and the effect of cdc42 deletion on the angiogenesis and embryonic development.

Hu GD, Chen YH, Zhang L, Tong WC, Cheng YX, Luo YL, Cai SX, Zhang L.

Chin Med J (Engl). 2011 Dec;124(24):4155-9.

PMID:
22340378
8.

A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse.

Jiménez AJ, Tomé M, Páez P, Wagner C, Rodríguez S, Fernández-Llebrez P, Rodríguez EM, Pérez-Fígares JM.

J Neuropathol Exp Neurol. 2001 Nov;60(11):1105-19.

PMID:
11706940
9.

Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium.

Ohata S, Herranz-Pérez V, Nakatani J, Boletta A, García-Verdugo JM, Álvarez-Buylla A.

J Neurosci. 2015 Aug 5;35(31):11153-68. doi: 10.1523/JNEUROSCI.0686-15.2015.

10.

Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development.

Li J, Liu Y, Jin Y, Wang R, Wang J, Lu S, VanBuren V, Dostal DE, Zhang SL, Peng X.

Dev Biol. 2017 Jan 15;421(2):271-283. doi: 10.1016/j.ydbio.2016.12.012. Epub 2016 Dec 14.

11.

Overexpression of nestin and vimentin in the ependyma of spinal cords from hydrocephalic infants.

Takano T, Becker LE.

Neuropathol Appl Neurobiol. 1997 Feb;23(1):3-15.

PMID:
9061685
12.

Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly.

Chen L, Liao G, Yang L, Campbell K, Nakafuku M, Kuan CY, Zheng Y.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16520-5. Epub 2006 Oct 18.

13.

New ependymal cells are born postnatally in two discrete regions of the mouse brain and support ventricular enlargement in hydrocephalus.

Bátiz LF, Jiménez AJ, Guerra M, Rodríguez-Pérez LM, Toledo CD, Vio K, Páez P, Pérez-Fígares JM, Rodríguez EM.

Acta Neuropathol. 2011 Jun;121(6):721-35. doi: 10.1007/s00401-011-0799-x. Epub 2011 Feb 11.

PMID:
21311902
14.

Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis.

Jin Y, Liu Y, Lin Q, Li J, Druso JE, Antonyak MA, Meininger CJ, Zhang SL, Dostal DE, Guan JL, Cerione RA, Peng X.

Mol Cell Biol. 2013 Nov;33(21):4181-97. doi: 10.1128/MCB.00650-13. Epub 2013 Aug 26.

15.

Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling.

Lin X, Liu B, Yang X, Yue X, Diao L, Wang J, Chang J.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8236-41. doi: 10.1073/pnas.1219995110. Epub 2013 Apr 29.

16.

High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly.

Forni PE, Scuoppo C, Imayoshi I, Taulli R, Dastrù W, Sala V, Betz UA, Muzzi P, Martinuzzi D, Vercelli AE, Kageyama R, Ponzetto C.

J Neurosci. 2006 Sep 13;26(37):9593-602.

17.

Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain.

Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y.

PLoS One. 2013 Nov 13;8(11):e80356. doi: 10.1371/journal.pone.0080356. eCollection 2013.

18.

Rho GTPase protein Cdc42 is critical for postnatal cartilage development.

Nagahama R, Yamada A, Tanaka J, Aizawa R, Suzuki D, Kassai H, Yamamoto M, Mishima K, Aiba A, Maki K, Kamijo R.

Biochem Biophys Res Commun. 2016 Feb 19;470(4):813-7. doi: 10.1016/j.bbrc.2016.01.111. Epub 2016 Jan 25.

PMID:
26820532
19.

Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice.

Barry DM, Xu K, Meadows SM, Zheng Y, Norden PR, Davis GE, Cleaver O.

Development. 2015 Sep 1;142(17):3058-70. doi: 10.1242/dev.125260. Epub 2015 Aug 7.

20.

Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.

Abouhamed M, Grobe K, San IV, Thelen S, Honnert U, Balda MS, Matter K, Bähler M.

Mol Biol Cell. 2009 Dec;20(24):5074-85. doi: 10.1091/mbc.E09-04-0291.

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