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Items: 1 to 20 of 91

1.

DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells.

Lee JH, Gaddameedhi S, Ozturk N, Ye R, Sancar A.

Cancer Res. 2013 Jan 15;73(2):785-91. doi: 10.1158/0008-5472.CAN-12-1994. Epub 2012 Nov 13.

2.

Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis.

Lee JH, Sancar A.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10668-72. doi: 10.1073/pnas.1106284108. Epub 2011 May 31.

3.

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.

Anand SN, Maywood ES, Chesham JE, Joynson G, Banks GT, Hastings MH, Nolan PM.

J Neurosci. 2013 Apr 24;33(17):7145-53. doi: 10.1523/JNEUROSCI.4950-12.2013.

4.

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants.

Lanza M, Marinari B, Papoutsaki M, Giustizieri ML, D'Alessandra Y, Chimenti S, Guerrini L, Costanzo A.

Cell Cycle. 2006 Sep;5(17):1996-2004. Epub 2006 Sep 1.

PMID:
16931914
5.

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, Takahashi JS, Sancar A.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12114-9.

6.

GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria.

John K, Alla V, Meier C, Pützer BM.

Cell Death Differ. 2011 May;18(5):874-86. doi: 10.1038/cdd.2010.153. Epub 2010 Dec 3. Erratum in: Cell Death Differ. 2012 Mar;19(3):552.

7.

Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner.

Destici E, Oklejewicz M, Saito S, van der Horst GT.

Cell Cycle. 2011 Nov 1;10(21):3788-97. doi: 10.4161/cc.10.21.17974. Epub 2011 Nov 1.

PMID:
22033214
8.

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

Papp SJ, Huber AL, Jordan SD, Kriebs A, Nguyen M, Moresco JJ, Yates JR, Lamia KA.

Elife. 2015 Mar 10;4. doi: 10.7554/eLife.04883.

9.

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

Bell HS, Dufes C, O'Prey J, Crighton D, Bergamaschi D, Lu X, Schätzlein AG, Vousden KH, Ryan KM.

J Clin Invest. 2007 Apr;117(4):1008-18. Epub 2007 Mar 8.

10.

Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.

Hashiramoto A, Yamane T, Tsumiyama K, Yoshida K, Komai K, Yamada H, Yamazaki F, Doi M, Okamura H, Shiozawa S.

J Immunol. 2010 Feb 1;184(3):1560-5. doi: 10.4049/jimmunol.0903284. Epub 2009 Dec 30.

11.

Deregulated expression of cryptochrome genes in human colorectal cancer.

Mazzoccoli G, Colangelo T, Panza A, Rubino R, De Cata A, Tiberio C, Valvano MR, Pazienza V, Merla G, Augello B, Trombetta D, Storlazzi CT, Macchia G, Gentile A, Tavano F, Vinciguerra M, Bisceglia G, Rosato V, Colantuoni V, Sabatino L, Piepoli A.

Mol Cancer. 2016 Jan 15;15:6. doi: 10.1186/s12943-016-0492-8.

12.

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE.

Nat Cell Biol. 2003 Jul;5(7):655-60.

PMID:
12833065
13.

Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.

Ambrosini G, Sambol EB, Carvajal D, Vassilev LT, Singer S, Schwartz GK.

Oncogene. 2007 May 24;26(24):3473-81. Epub 2006 Dec 4.

PMID:
17146434
14.

Regulation of apoptosis by the circadian clock through NF-kappaB signaling.

Lee JH, Sancar A.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12036-41. doi: 10.1073/pnas.1108125108. Epub 2011 Jun 20.

15.

p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells.

Fatt MP, Cancino GI, Miller FD, Kaplan DR.

Cell Death Differ. 2014 Oct;21(10):1546-59. doi: 10.1038/cdd.2014.61. Epub 2014 May 9.

16.

Role of the p53-homologue p73 in E2F1-induced apoptosis.

Stiewe T, Pützer BM.

Nat Genet. 2000 Dec;26(4):464-9.

PMID:
11101847
17.

p73 cooperates with DNA damage agents to induce apoptosis in MCF7 cells in a p53-dependent manner.

Zhu J, Nozell S, Wang J, Jiang J, Zhou W, Chen X.

Oncogene. 2001 Jul 5;20(30):4050-7.

18.

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.

Yu J, Baron V, Mercola D, Mustelin T, Adamson ED.

Cell Death Differ. 2007 Mar;14(3):436-46. Epub 2006 Sep 22. Erratum in: Cell Death Differ. 2007 Mar;14(3):640.

19.

DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest.

Vossio S, Palescandolo E, Pediconi N, Moretti F, Balsano C, Levrero M, Costanzo A.

Oncogene. 2002 May 23;21(23):3796-803.

20.

The consequence of p53 overexpression for liver tumor development and the response of transformed murine hepatocytes to genotoxic agents.

Gillet R, Grimber G, Bennoun M, Caron de Fromentel C, Briand P, Joulin V.

Oncogene. 2000 Jul 20;19(31):3498-507.

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