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Items: 1 to 20 of 111

1.
2.

The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3.

Lin YC, Huang DY, Chu CL, Lin YL, Lin WW.

Sci Signal. 2013 Aug 20;6(289):ra71. doi: 10.1126/scisignal.2003973.

PMID:
23962979
3.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

4.

TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.

Morlon A, Munnich A, Smahi A.

Hum Mol Genet. 2005 Dec 1;14(23):3751-7. Epub 2005 Oct 26.

PMID:
16251197
5.

Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.

Moon G, Kim J, Min Y, Wi SM, Shim JH, Chun E, Lee KY.

Cell Signal. 2015 Dec;27(12):2524-33. doi: 10.1016/j.cellsig.2015.09.018. Epub 2015 Sep 30.

PMID:
26432169
6.

Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation.

Gu M, Ouyang C, Lin W, Zhang T, Cao X, Xia Z, Wang X.

J Immunol. 2014 Mar 15;192(6):2846-56. doi: 10.4049/jimmunol.1302537. Epub 2014 Feb 17. Erratum in: J Immunol. 2015 Aug 1;195(3):1331-2.

7.

TAK1-ECSIT-TRAF6 complex plays a key role in the TLR4 signal to activate NF-κB.

Wi SM, Moon G, Kim J, Kim ST, Shim JH, Chun E, Lee KY.

J Biol Chem. 2014 Dec 19;289(51):35205-14. doi: 10.1074/jbc.M114.597187. Epub 2014 Nov 4.

8.

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6.

Mizukami J, Takaesu G, Akatsuka H, Sakurai H, Ninomiya-Tsuji J, Matsumoto K, Sakurai N.

Mol Cell Biol. 2002 Feb;22(4):992-1000.

9.
10.

The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans.

Wells CA, Salvage-Jones JA, Li X, Hitchens K, Butcher S, Murray RZ, Beckhouse AG, Lo YL, Manzanero S, Cobbold C, Schroder K, Ma B, Orr S, Stewart L, Lebus D, Sobieszczuk P, Hume DA, Stow J, Blanchard H, Ashman RB.

J Immunol. 2008 Jun 1;180(11):7404-13.

11.

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.

Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S.

Genes Dev. 2005 Nov 15;19(22):2668-81. Epub 2005 Oct 31.

12.

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA.

J Biol Chem. 2007 Dec 14;282(50):36223-9. Epub 2007 Oct 18.

13.

TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.

Lamothe B, Lai Y, Xie M, Schneider MD, Darnay BG.

Mol Cell Biol. 2013 Feb;33(3):582-95. doi: 10.1128/MCB.01225-12. Epub 2012 Nov 19.

14.

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta.

Jiang Z, Mak TW, Sen G, Li X.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3533-8. Epub 2004 Feb 24.

15.

TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB.

Lee SW, Han SI, Kim HH, Lee ZH.

J Biochem Mol Biol. 2002 Jul 31;35(4):371-6.

PMID:
12296995
16.

Grass carp (Ctenopharyngodon idella) TRAF6 and TAK1: molecular cloning and expression analysis after Ichthyophthirius multifiliis infection.

Zhao F, Li YW, Pan HJ, Wu SQ, Shi CB, Luo XC, Li AX.

Fish Shellfish Immunol. 2013 Jun;34(6):1514-23. doi: 10.1016/j.fsi.2013.03.003. Epub 2013 Mar 28.

PMID:
23542602
17.

Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

Parti RP, Loper R, Brown GD, Gordon S, Taylor PR, Bonventre JV, Murphy RC, Williams DL, Leslie CC.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):415-23. doi: 10.1165/rcmb.2009-0110OC. Epub 2009 Jun 5.

18.

Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts.

Gu J, Liu X, Wang QX, Tan HW, Guo M, Jiang WF, Zhou L.

Exp Cell Res. 2012 Oct 1;318(16):2105-15. doi: 10.1016/j.yexcr.2012.06.015. Epub 2012 Jun 27.

PMID:
22749815
19.

TNFR-associated factor 6 and TGF-β-activated kinase 1 control signals for a senescence response by an endosomal NK cell receptor.

Rajagopalan S, Lee EC, DuPrie ML, Long EO.

J Immunol. 2014 Jan 15;192(2):714-21. doi: 10.4049/jimmunol.1302384. Epub 2013 Dec 11.

20.

Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophages.

Sun H, Xu XY, Tian XL, Shao HT, Wu XD, Wang Q, Su X, Shi Y.

Immunobiology. 2014 Jan;219(1):25-36. doi: 10.1016/j.imbio.2013.06.013. Epub 2013 Jul 4.

PMID:
23886693

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