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Items: 1 to 20 of 98

1.

Statins, autophagy and cancer metastasis.

Zhang J, Yang Z, Xie L, Xu L, Xu D, Liu X.

Int J Biochem Cell Biol. 2013 Mar;45(3):745-52. doi: 10.1016/j.biocel.2012.11.001. Epub 2012 Nov 10. Review.

PMID:
23147595
2.

Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer.

Graaf MR, Richel DJ, van Noorden CJ, Guchelaar HJ.

Cancer Treat Rev. 2004 Nov;30(7):609-41. Review.

PMID:
15531395
3.

Clinical confirmation of an anti-metastasis effect from statins.

Sorscher S.

Int J Biochem Cell Biol. 2014 Dec;57:207. doi: 10.1016/j.biocel.2014.09.029. Epub 2014 Oct 13. No abstract available.

PMID:
25310901
4.

Statins and cancer.

Vallianou NG, Kostantinou A, Kougias M, Kazazis C.

Anticancer Agents Med Chem. 2014 Jun;14(5):706-12. Review.

PMID:
24295174
5.

Hydrophobic statins induce autophagy and cell death in human rhabdomyosarcoma cells by depleting geranylgeranyl diphosphate.

Araki M, Maeda M, Motojima K.

Eur J Pharmacol. 2012 Jan 15;674(2-3):95-103. doi: 10.1016/j.ejphar.2011.10.044. Epub 2011 Nov 9.

PMID:
22094060
6.
7.

Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I.

Martin G, Duez H, Blanquart C, Berezowski V, Poulain P, Fruchart JC, Najib-Fruchart J, Glineur C, Staels B.

J Clin Invest. 2001 Jun;107(11):1423-32.

8.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
9.

Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy.

Danesh FR, Kanwar YS.

FASEB J. 2004 May;18(7):805-15. Review.

PMID:
15117885
10.

Potential antitumor effects of statins (Review).

Jakobisiak M, Golab J.

Int J Oncol. 2003 Oct;23(4):1055-69. Review.

PMID:
12963986
11.

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.

Danesh FR, Sadeghi MM, Amro N, Philips C, Zeng L, Lin S, Sahai A, Kanwar YS.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8301-5. Epub 2002 Jun 4.

12.
13.

Statins, stem cells, and cancer.

Gauthaman K, Fong CY, Bongso A.

J Cell Biochem. 2009 Apr 15;106(6):975-83. doi: 10.1002/jcb.22092. Review.

PMID:
19224538
14.

Pleiotropic effects of statins. - Basic research and clinical perspectives -.

Zhou Q, Liao JK.

Circ J. 2010 May;74(5):818-26. Epub 2010 Apr 15. Review.

15.

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy.

Yang Z, Su Z, DeWitt JP, Xie L, Chen Y, Li X, Han L, Li D, Xia J, Zhang Y, Yang Y, Jin C, Zhang J, Li S, Li K, Zhang Z, Qu X, He Z, Chen Y, Shen Y, Ren M, Yuan Z.

EBioMedicine. 2017 May;19:49-59. doi: 10.1016/j.ebiom.2017.04.017. Epub 2017 Apr 11.

16.

Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells.

Parikh A, Childress C, Deitrick K, Lin Q, Rukstalis D, Yang W.

Prostate. 2010 Jun 15;70(9):971-81. doi: 10.1002/pros.21131.

PMID:
20135644
17.

Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.

Yang PM, Liu YL, Lin YC, Shun CT, Wu MS, Chen CC.

Cancer Res. 2010 Oct 1;70(19):7699-709. doi: 10.1158/0008-5472.CAN-10-1626. Epub 2010 Sep 28.

18.

Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors.

Yang PM, Chen CC.

Autophagy. 2011 Jan;7(1):107-8. Epub 2011 Jan 1.

PMID:
21057221
19.

Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.

Bi X, Baudry M, Liu J, Yao Y, Fu L, Brucher F, Lynch G.

J Biol Chem. 2004 Nov 12;279(46):48238-45. Epub 2004 Sep 9.

20.

Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells.

Wang N, Pan W, Zhu M, Zhang M, Hao X, Liang G, Feng Y.

Br J Pharmacol. 2011 Sep;164(2b):731-42. doi: 10.1111/j.1476-5381.2011.01349.x.

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