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Items: 1 to 20 of 126

1.

An insertion in the catalytic trigger loop gates the secondary channel of RNA polymerase.

Furman R, Tsodikov OV, Wolf YI, Artsimovitch I.

J Mol Biol. 2013 Jan 9;425(1):82-93. doi: 10.1016/j.jmb.2012.11.008. Epub 2012 Nov 9.

2.

Effects of DksA, GreA, and GreB on transcription initiation: insights into the mechanisms of factors that bind in the secondary channel of RNA polymerase.

Rutherford ST, Lemke JJ, Vrentas CE, Gaal T, Ross W, Gourse RL.

J Mol Biol. 2007 Mar 2;366(4):1243-57. Epub 2006 Dec 12.

3.

Transcription initiation factor DksA has diverse effects on RNA chain elongation.

Furman R, Sevostyanova A, Artsimovitch I.

Nucleic Acids Res. 2012 Apr;40(8):3392-402. doi: 10.1093/nar/gkr1273. Epub 2011 Dec 30.

4.

Antagonistic regulation of Escherichia coli ribosomal RNA rrnB P1 promoter activity by GreA and DksA.

Potrykus K, Vinella D, Murphy H, Szalewska-Palasz A, D'Ari R, Cashel M.

J Biol Chem. 2006 Jun 2;281(22):15238-48. Epub 2006 Apr 5.

5.

Direct interactions between the coiled-coil tip of DksA and the trigger loop of RNA polymerase mediate transcriptional regulation.

Lennon CW, Ross W, Martin-Tumasz S, Toulokhonov I, Vrentas CE, Rutherford ST, Lee JH, Butcher SE, Gourse RL.

Genes Dev. 2012 Dec 1;26(23):2634-46. doi: 10.1101/gad.204693.112.

6.

Effects on growth by changes of the balance between GreA, GreB, and DksA suggest mutual competition and functional redundancy in Escherichia coli.

Vinella D, Potrykus K, Murphy H, Cashel M.

J Bacteriol. 2012 Jan;194(2):261-73. doi: 10.1128/JB.06238-11. Epub 2011 Nov 4.

7.

The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.

Vassylyeva MN, Svetlov V, Dearborn AD, Klyuyev S, Artsimovitch I, Vassylyev DG.

EMBO Rep. 2007 Nov;8(11):1038-43. Epub 2007 Oct 5.

8.

Characterization of a novel RNA polymerase mutant that alters DksA activity.

Satory D, Halliday JA, Sivaramakrishnan P, Lua RC, Herman C.

J Bacteriol. 2013 Sep;195(18):4187-94. doi: 10.1128/JB.00382-13. Epub 2013 Jul 12.

9.

TraR, a homolog of a RNAP secondary channel interactor, modulates transcription.

Blankschien MD, Potrykus K, Grace E, Choudhary A, Vinella D, Cashel M, Herman C.

PLoS Genet. 2009 Jan;5(1):e1000345. doi: 10.1371/journal.pgen.1000345. Epub 2009 Jan 16.

10.

Role of the coiled-coil tip of Escherichia coli DksA in promoter control.

Lee JH, Lennon CW, Ross W, Gourse RL.

J Mol Biol. 2012 Mar 2;416(4):503-17. doi: 10.1016/j.jmb.2011.12.028. Epub 2011 Dec 19.

11.

Mutations in RNA Polymerase Bridge Helix and Switch Regions Affect Active-Site Networks and Transcript-Assisted Hydrolysis.

Zhang N, Schäfer J, Sharma A, Rayner L, Zhang X, Tuma R, Stockley P, Buck M.

J Mol Biol. 2015 Nov 6;427(22):3516-3526. doi: 10.1016/j.jmb.2015.09.005. Epub 2015 Sep 10.

12.

Coupling of downstream RNA polymerase-promoter interactions with formation of catalytically competent transcription initiation complex.

Mekler V, Minakhin L, Borukhov S, Mustaev A, Severinov K.

J Mol Biol. 2014 Dec 12;426(24):3973-84. doi: 10.1016/j.jmb.2014.10.005. Epub 2014 Oct 13.

13.

Transcription Elongation Factor NusA Is a General Antagonist of Rho-dependent Termination in Escherichia coli.

Qayyum MZ, Dey D, Sen R.

J Biol Chem. 2016 Apr 8;291(15):8090-108. doi: 10.1074/jbc.M115.701268. Epub 2016 Feb 12.

14.

Escherichia coli DksA binds to Free RNA polymerase with higher affinity than to RNA polymerase in an open complex.

Lennon CW, Gaal T, Ross W, Gourse RL.

J Bacteriol. 2009 Sep;191(18):5854-8. doi: 10.1128/JB.00621-09. Epub 2009 Jul 17.

15.

Allosteric control of Escherichia coli rRNA promoter complexes by DksA.

Rutherford ST, Villers CL, Lee JH, Ross W, Gourse RL.

Genes Dev. 2009 Jan 15;23(2):236-48. doi: 10.1101/gad.1745409.

16.

Early transcriptional arrest at Escherichia coli rplN and ompX promoters.

Stepanova E, Wang M, Severinov K, Borukhov S.

J Biol Chem. 2009 Dec 18;284(51):35702-13. doi: 10.1074/jbc.M109.053983.

17.

Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase.

Laptenko O, Lee J, Lomakin I, Borukhov S.

EMBO J. 2003 Dec 1;22(23):6322-34.

18.

DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1.

Parshin A, Shiver AL, Lee J, Ozerova M, Schneidman-Duhovny D, Gross CA, Borukhov S.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6862-71. doi: 10.1073/pnas.1521365112. Epub 2015 Nov 24. Erratum in: Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E103.

19.

The dual role of DksA protein in the regulation of Escherichia coli pArgX promoter.

Łyżeń R, Maitra A, Milewska K, Kochanowska-Łyżeń M, Hernandez VJ, Szalewska-Pałasz A.

Nucleic Acids Res. 2016 Dec 1;44(21):10316-10325. Epub 2016 Oct 7.

20.

DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest.

Zhang Y, Mooney RA, Grass JA, Sivaramakrishnan P, Herman C, Landick R, Wang JD.

Mol Cell. 2014 Mar 6;53(5):766-78. doi: 10.1016/j.molcel.2014.02.005.

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