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Items: 1 to 20 of 98

1.

Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model.

Berger T, Ueda T, Arpaia E, Chio II, Shirdel EA, Jurisica I, Hamada K, You-Ten A, Haight J, Wakeham A, Cheung CC, Mak TW.

Oncogene. 2013 Oct 10;32(41):4989-94. doi: 10.1038/onc.2012.499. Epub 2012 Nov 12.

PMID:
23146906
2.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

3.

Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.

Roselli S, Kahl RG, Copeland BT, Naylor MJ, Weidenhofer J, Muller WJ, Ashman LK.

BMC Cancer. 2014 Jul 11;14:509. doi: 10.1186/1471-2407-14-509.

4.

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.

Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, Smith KD, Cushing RC, Seagroves TN.

Breast Cancer Res. 2012 Jan 7;14(1):R6.

5.

Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis.

Berger T, Cheung CC, Elia AJ, Mak TW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2995-3000. doi: 10.1073/pnas.1000101107. Epub 2010 Feb 1.

6.

Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors.

Roussos ET, Wang Y, Wyckoff JB, Sellers RS, Wang W, Li J, Pollard JW, Gertler FB, Condeelis JS.

Breast Cancer Res. 2010;12(6):R101. doi: 10.1186/bcr2784. Epub 2010 Nov 25.

7.

Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.

Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J.

Breast Cancer Res. 2012 Jan 25;14(1):R18.

8.

Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.

Franci C, Zhou J, Jiang Z, Modrusan Z, Good Z, Jackson E, Kouros-Mehr H.

PLoS One. 2013;8(3):e58183. doi: 10.1371/journal.pone.0058183. Epub 2013 Mar 8.

10.

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

Vasiljeva O, Papazoglou A, Krüger A, Brodoefel H, Korovin M, Deussing J, Augustin N, Nielsen BS, Almholt K, Bogyo M, Peters C, Reinheckel T.

Cancer Res. 2006 May 15;66(10):5242-50.

11.

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.

Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Müller S, Follo M, Peters C, Reinheckel T.

Oncogene. 2011 Jan 6;30(1):54-64. doi: 10.1038/onc.2010.387. Epub 2010 Sep 6.

PMID:
20818432
12.

Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.

Qiu TH, Chandramouli GV, Hunter KW, Alkharouf NW, Green JE, Liu ET.

Cancer Res. 2004 Sep 1;64(17):5973-81.

13.

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.

Almholt K, Juncker-Jensen A, Laerum OD, Danø K, Johnsen M, Lund LR, Rømer J.

Mol Cancer Ther. 2008 Sep;7(9):2758-67. doi: 10.1158/1535-7163.MCT-08-0251.

14.

A novel role for flotillin-1 in H-Ras-regulated breast cancer aggressiveness.

Koh M, Yong HY, Kim ES, Son H, Jeon YR, Hwang JS, Kim MO, Cha Y, Choi WS, Noh DY, Lee KM, Kim KB, Lee JS, Kim HJ, Kim H, Kim HH, Kim EJ, Park SY, Kim HS, Moon WK, Choi Kim HR, Moon A.

Int J Cancer. 2016 Mar 1;138(5):1232-45. doi: 10.1002/ijc.29869. Epub 2015 Oct 9.

16.

An improved model to study tumor cell autonomous metastasis programs using MTLn3 cells and the Rag2(-/-) gammac (-/-) mouse.

Le Dévédec SE, van Roosmalen W, Maria N, Grimbergen M, Pont C, Lalai R, van de Water B.

Clin Exp Metastasis. 2009;26(7):673-84. doi: 10.1007/s10585-009-9267-6. Epub 2009 May 24.

17.

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.

Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmbäck K, Drew AF, Flick MJ, Witte DP, Danø K, Degen JL.

Oncogene. 1998 Jun 18;16(24):3097-104.

18.

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice.

Decock J, Hendrickx W, Thirkettle S, Gutiérrez-Fernández A, Robinson SD, Edwards DR.

Breast Cancer Res. 2015 Mar 14;17:38. doi: 10.1186/s13058-015-0545-8.

19.

Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.

Bojovic B, Crowe DL.

Mol Carcinog. 2013 Feb;52(2):103-17. doi: 10.1002/mc.21834. Epub 2011 Nov 15.

PMID:
22086874
20.

Flotillin-2 is associated with breast cancer progression and poor survival outcomes.

Wang X, Yang Q, Guo L, Li XH, Zhao XH, Song LB, Lin HX.

J Transl Med. 2013 Aug 15;11:190. doi: 10.1186/1479-5876-11-190.

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