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Items: 1 to 20 of 76

1.
2.

A comparative study of disease genes and drug targets in the human protein interactome.

Sun J, Zhu K, Zheng W, Xu H.

BMC Bioinformatics. 2015;16 Suppl 5:S1. doi: 10.1186/1471-2105-16-S5-S1.

3.

Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations.

Perez-Lopez ÁR, Szalay KZ, Türei D, Módos D, Lenti K, Korcsmáros T, Csermely P.

Sci Rep. 2015 May 11;5:10182. doi: 10.1038/srep10182.

4.

Network-based characterization of drug-regulated genes, drug targets, and toxicity.

Kotlyar M, Fortney K, Jurisica I.

Methods. 2012 Aug;57(4):499-507. doi: 10.1016/j.ymeth.2012.06.003. Review.

5.

The analysis of the drug-targets based on the topological properties in the human protein-protein interaction network.

Zhu M, Gao L, Li X, Liu Z, Xu C, Yan Y, Walker E, Jiang W, Su B, Chen X, Lin H.

J Drug Target. 2009 Aug;17(7):524-32. doi: 10.1080/10611860903046610.

PMID:
19530902
6.

iRefR: an R package to manipulate the iRefIndex consolidated protein interaction database.

Mora A, Donaldson IM.

BMC Bioinformatics. 2011 Nov 24;12:455. doi: 10.1186/1471-2105-12-455.

7.

A Topology Potential-Based Method for Identifying Essential Proteins from PPI Networks.

Li M, Lu Y, Wang J, Wu FX, Pan Y.

IEEE/ACM Trans Comput Biol Bioinform. 2015 Mar-Apr;12(2):372-83. doi: 10.1109/TCBB.2014.2361350.

PMID:
26357224
8.

Model-based clustering reveals vitamin D dependent multi-centrality hubs in a network of vitamin-related proteins.

Nguyen TP, Scotti M, Morine MJ, Priami C.

BMC Syst Biol. 2011 Dec 2;5:195. doi: 10.1186/1752-0509-5-195.

9.

Finding the targets of a drug by integration of gene expression data with a protein interaction network.

Laenen G, Thorrez L, Börnigen D, Moreau Y.

Mol Biosyst. 2013 Jul;9(7):1676-85. doi: 10.1039/c3mb25438k.

PMID:
23443074
10.

A local average connectivity-based method for identifying essential proteins from the network level.

Li M, Wang J, Chen X, Wang H, Pan Y.

Comput Biol Chem. 2011 Jun;35(3):143-50. doi: 10.1016/j.compbiolchem.2011.04.002.

PMID:
21704260
11.

A new method for the discovery of essential proteins.

Zhang X, Xu J, Xiao WX.

PLoS One. 2013;8(3):e58763. doi: 10.1371/journal.pone.0058763.

12.

Improving protein function prediction methods with integrated literature data.

Gabow AP, Leach SM, Baumgartner WA, Hunter LE, Goldberg DS.

BMC Bioinformatics. 2008 Apr 15;9:198. doi: 10.1186/1471-2105-9-198.

13.

Protein interaction networks as starting points to identify novel antimicrobial drug targets.

Zoraghi R, Reiner NE.

Curr Opin Microbiol. 2013 Oct;16(5):566-72. doi: 10.1016/j.mib.2013.07.010. Review.

PMID:
23938265
14.

Exploring the relationship between hub proteins and drug targets based on GO and intrinsic disorder.

Fu Y, Guo Y, Wang Y, Luo J, Pu X, Li M, Zhang Z.

Comput Biol Chem. 2015 Jun;56:41-8. doi: 10.1016/j.compbiolchem.2015.03.003.

PMID:
25854804
15.

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.

Kirouac DC, Saez-Rodriguez J, Swantek J, Burke JM, Lauffenburger DA, Sorger PK.

BMC Syst Biol. 2012 May 1;6:29. doi: 10.1186/1752-0509-6-29.

16.

Predicting new molecular targets for rhein using network pharmacology.

Zhang A, Sun H, Yang B, Wang X.

BMC Syst Biol. 2012 Mar 21;6:20. doi: 10.1186/1752-0509-6-20. Retraction in: Zhang A, Sun H, Yang B, Wang X. BMC Syst Biol. 2014;8:105.

17.

Oncogenes and tumor suppressor genes: comparative genomics and network perspectives.

Zhu K, Liu Q, Zhou Y, Tao C, Zhao Z, Sun J, Xu H.

BMC Genomics. 2015;16 Suppl 7:S8. doi: 10.1186/1471-2164-16-S7-S8.

18.

Information flow analysis of interactome networks.

Missiuro PV, Liu K, Zou L, Ross BC, Zhao G, Liu JS, Ge H.

PLoS Comput Biol. 2009 Apr;5(4):e1000350. doi: 10.1371/journal.pcbi.1000350.

19.

Removing bias against membrane proteins in interaction networks.

Brito GC, Andrews DW.

BMC Syst Biol. 2011 Oct 19;5:169. doi: 10.1186/1752-0509-5-169.

20.

Predicting adverse drug reaction profiles by integrating protein interaction networks with drug structures.

Huang LC, Wu X, Chen JY.

Proteomics. 2013 Jan;13(2):313-24. doi: 10.1002/pmic.201200337.

PMID:
23184540

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