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Items: 1 to 20 of 108

1.

Large scale synthesis of 2'-amino-LNA thymine and 5-methylcytosine nucleosides.

Madsen AS, Jørgensen AS, Jensen TB, Wengel J.

J Org Chem. 2012 Dec 7;77(23):10718-28. doi: 10.1021/jo302036h. Epub 2012 Nov 26.

PMID:
23145501
2.

LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis.

Madsen AS, Kumar TS, Wengel J.

Org Biomol Chem. 2010 Nov 7;8(21):5012-6. doi: 10.1039/c0ob00346h. Epub 2010 Sep 3.

PMID:
20820663
3.

Synthesis and biophysical studies of N2'-functionalized 2'-amino-alpha-L-LNA.

Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ.

Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1403-5.

PMID:
18066792
4.

Synthesis and hybridization studies of 2'-amino-alpha-L-LNA and tetracyclic "locked LNA".

Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ.

J Org Chem. 2006 May 26;71(11):4188-201.

PMID:
16709060
5.

Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.

Kumar TS, Madsen AS, Østergaard ME, Sau SP, Wengel J, Hrdlicka PJ.

J Org Chem. 2009 Feb 6;74(3):1070-81. doi: 10.1021/jo802037v.

6.

Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues.

Seth PP, Vasquez G, Allerson CA, Berdeja A, Gaus H, Kinberger GA, Prakash TP, Migawa MT, Bhat B, Swayze EE.

J Org Chem. 2010 Mar 5;75(5):1569-81. doi: 10.1021/jo902560f.

PMID:
20136157
7.

N2'-functionalized 2'-amino-alpha-L-LNA adenine derivatives--efficient targeting of single stranded DNA.

Andersen NK, Wengel J, Hrdlicka PJ.

Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1415-7.

PMID:
18066795
8.

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Vanheusden V, Munier-Lehmann H, Froeyen M, Dugué L, Heyerick A, De Keukeleire D, Pochet S, Busson R, Herdewijn P, Van Calenbergh S.

J Med Chem. 2003 Aug 28;46(18):3811-21.

PMID:
12930144
9.

Exomethylene pyranonucleosides: efficient synthesis and biological evaluation of 1-(2,3,4-trideoxy-2-methylene-beta-d-glycero-hex-3-enopyranosyl)thymine.

Agelis G, Tzioumaki N, Botić T, Cencic A, Komiotis D.

Bioorg Med Chem. 2007 Aug 15;15(16):5448-56. Epub 2007 May 26.

PMID:
17555969
10.

A thymine tetrad assembly templated from thymidylic acid.

Bare GA, Sherman JC.

J Org Chem. 2013 Aug 16;78(16):8198-202. doi: 10.1021/jo401281p. Epub 2013 Aug 6.

PMID:
23875642
11.

Triplex-forming ability of modified oligonucleotides.

Højland T, Babu BR, Bryld T, Wengel J.

Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1411-4.

PMID:
18066794
12.

Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites.

Kumar TS, Madsen AS, Østergaard ME, Wengel J, Hrdlicka PJ.

J Org Chem. 2008 Sep 19;73(18):7060-6. doi: 10.1021/jo800551j. Epub 2008 Aug 19.

PMID:
18710289
13.

Synthesis and biophysical studies of coronene functionalized 2'-amino-LNA: a novel class of fluorescent nucleic acids.

Gupta P, Langkjær N, Wengel J.

Bioconjug Chem. 2010 Mar 17;21(3):513-20. doi: 10.1021/bc900421r. Epub 2010 Jan 25.

PMID:
20099893
14.

An efficient solid phase synthesis of 5'-phosphodiester and phosphoramidate monoester nucleoside analogues.

De Napoli L, Di Fabio G, D'Onofrio J, Montesarchio D.

Chem Commun (Camb). 2005 May 28;(20):2586-8. Epub 2005 Mar 29.

PMID:
15900335
15.

Nucleosides with 1,4-dioxane as sugar moiety.

Madsen AS, Langkjaer N, Wengel J.

Nucleic Acids Symp Ser (Oxf). 2008;(52):269-70. doi: 10.1093/nass/nrn136.

PMID:
18776357
16.

Janus-type AT nucleosides: synthesis, solid and solution state structures.

Pan MY, Hang W, Zhao XJ, Zhao H, Deng PC, Xing ZH, Qing Y, He Y.

Org Biomol Chem. 2011 Aug 21;9(16):5692-702. doi: 10.1039/c1ob05577a. Epub 2011 Jun 27.

PMID:
21709903
17.
18.

7-substituted 8-aza-7-deazapurines and 2,8-diaza-7-deaza-purines: synthesis of nucleosides and oligonucleotides.

Lin W, Xu K, Seela F.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):869-73.

PMID:
16248052
19.

Glycosylation of nucleoside bases with 2,3-dideoxy-1-thio-D-glycero-pento-2-enofuranosides.

Sujino K, Yoshida T, Sugimura H.

Nucleic Acids Symp Ser. 1995;(34):19-20.

PMID:
8841531
20.

Nucleoside phosphitylation using ionic liquid stabilised phosphorodiamidites and mechanochemistry.

Crossey K, Hardacre C, Migaud ME.

Chem Commun (Camb). 2012 Dec 21;48(98):11969-71. doi: 10.1039/c2cc36367d.

PMID:
23128063

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