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Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse.

Matsakas A, Romanello V, Sartori R, Masiero E, Macharia R, Otto A, Elashry M, Sandri M, Patel K.

Int J Sports Med. 2013 Mar;34(3):223-31. doi: 10.1055/s-0032-1312605. Epub 2012 Nov 9.


Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse.

Matsakas A, Macharia R, Otto A, Elashry MI, Mouisel E, Romanello V, Sartori R, Amthor H, Sandri M, Narkar V, Patel K.

Exp Physiol. 2012 Jan;97(1):125-40. doi: 10.1113/expphysiol.2011.063008. Epub 2011 Nov 4.


Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice.

Elashry MI, Collins-Hooper H, Vaiyapuri S, Patel K.

J Anat. 2012 Jun;220(6):603-11. doi: 10.1111/j.1469-7580.2012.01503.x. Epub 2012 Mar 30.


Grip force, EDL contractile properties, and voluntary wheel running after postdevelopmental myostatin depletion in mice.

Personius KE, Jayaram A, Krull D, Brown R, Xu T, Han B, Burgess K, Storey C, Shah B, Tawil R, Welle S.

J Appl Physiol (1985). 2010 Sep;109(3):886-94. doi: 10.1152/japplphysiol.00300.2010. Epub 2010 Jul 1.


The effect of caloric restriction on the forelimb skeletal muscle fibers of the hypertrophic myostatin null mice.

Elashry MI, Matsakas A, Wenisch S, Arnhold S, Patel K.

Acta Histochem. 2017 Jun 13. pii: S0065-1281(17)30128-9. doi: 10.1016/j.acthis.2017.06.002. [Epub ahead of print]


Hindlimb skeletal muscle function in myostatin-deficient mice.

Gentry BA, Ferreira JA, Phillips CL, Brown M.

Muscle Nerve. 2011 Jan;43(1):49-57. doi: 10.1002/mus.21796.


Myostatin knockout mice increase oxidative muscle phenotype as an adaptive response to exercise.

Matsakas A, Mouisel E, Amthor H, Patel K.

J Muscle Res Cell Motil. 2010 Aug;31(2):111-25. doi: 10.1007/s10974-010-9214-9. Epub 2010 Jun 22.


Symmorphosis through dietary regulation: a combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation.

Collins-Hooper H, Sartori R, Giallourou N, Matsakas A, Mitchell R, Makarenkova HP, Flasskamp H, Macharia R, Ray S, Swann JR, Sandri M, Patel K.

PLoS One. 2015 Mar 25;10(3):e0120524. doi: 10.1371/journal.pone.0120524. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128731. Mararenkova, Helen [corrected to Makarenkova, Helen P].


Elevated insulin-like growth factor 2 expression may contribute to the hypermuscular phenotype of myostatin null mice.

Clark DL, Clark DI, Hogan EK, Kroscher KA, Dilger AC.

Growth Horm IGF Res. 2015 Oct;25(5):207-18. doi: 10.1016/j.ghir.2015.06.007. Epub 2015 Jun 26.


Lack of myostatin results in excessive muscle growth but impaired force generation.

Amthor H, Macharia R, Navarrete R, Schuelke M, Brown SC, Otto A, Voit T, Muntoni F, Vrbóva G, Partridge T, Zammit P, Bunger L, Patel K.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1835-40. Epub 2007 Jan 31. Erratum in: Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4240.


Regulation of muscle mass by follistatin and activins.

Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, Cohn RD, Barton ER.

Mol Endocrinol. 2010 Oct;24(10):1998-2008. doi: 10.1210/me.2010-0127. Epub 2010 Sep 1.


Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice.

Qiao C, Li J, Jiang J, Zhu X, Wang B, Li J, Xiao X.

Hum Gene Ther. 2008 Mar;19(3):241-54. doi: 10.1089/hum.2007.159.


Prolonged absence of myostatin reduces sarcopenia.

Siriett V, Platt L, Salerno MS, Ling N, Kambadur R, Sharma M.

J Cell Physiol. 2006 Dec;209(3):866-73.


Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice.

Collins-Hooper H, Sartori R, Macharia R, Visanuvimol K, Foster K, Matsakas A, Flasskamp H, Ray S, Dash PR, Sandri M, Patel K.

J Gerontol A Biol Sci Med Sci. 2014 Sep;69(9):1049-59. doi: 10.1093/gerona/glt170. Epub 2014 Jan 11.


Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia.

Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA.

Biochem Biophys Res Commun. 2010 Jan 15;391(3):1548-54. doi: 10.1016/j.bbrc.2009.12.123. Epub 2009 Dec 28.


Morphology and myofiber composition of skeletal musculature of the forelimb in young and aged wild type and myostatin null mice.

Elashry MI, Otto A, Matsakas A, El-Morsy SE, Patel K.

Rejuvenation Res. 2009 Aug;12(4):269-81. doi: 10.1089/rej.2009.0870.


Alterations of temporalis muscle contractile force and histological content from the myostatin and Mdx deficient mouse.

Byron CD, Hamrick MW, Wingard CJ.

Arch Oral Biol. 2006 May;51(5):396-405. Epub 2005 Nov 2.


Axon and muscle spindle hyperplasia in the myostatin null mouse.

Elashry MI, Otto A, Matsakas A, El-Morsy SE, Jones L, Anderson B, Patel K.

J Anat. 2011 Feb;218(2):173-84. doi: 10.1111/j.1469-7580.2010.01327.x.


Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin.

Reisz-Porszasz S, Bhasin S, Artaza JN, Shen R, Sinha-Hikim I, Hogue A, Fielder TJ, Gonzalez-Cadavid NF.

Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E876-88. Epub 2003 Jun 24.


Reductions in expression of growth regulating genes in skeletal muscle with age in wild type and myostatin null mice.

Jones JC, Kroscher KA, Dilger AC.

BMC Physiol. 2014 Mar 28;14:3. doi: 10.1186/1472-6793-14-3.

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