Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 78

1.

Role of C-terminal negative charges and tyrosine residues in fibril formation of α-synuclein.

Izawa Y, Tateno H, Kameda H, Hirakawa K, Hato K, Yagi H, Hongo K, Mizobata T, Kawata Y.

Brain Behav. 2012 Sep;2(5):595-605. doi: 10.1002/brb3.86. Epub 2012 Aug 10.

2.

The role of the acidic domain of α-synuclein in amyloid fibril formation: a molecular dynamics study.

Park S, Yoon J, Jang S, Lee K, Shin S.

J Biomol Struct Dyn. 2016;34(2):376-83. doi: 10.1080/07391102.2015.1033016. Epub 2015 May 1.

PMID:
25869255
3.

The effect of tyrosine residues on α-synuclein fibrillation.

Pirc K, Škarabot M, Pogačnik L, Žerovnik E, Poklar-Ulrih N.

Acta Chim Slov. 2015;62(1):181-9.

PMID:
25830974
4.

Mechanistic insight into the relationship between N-terminal acetylation of α-synuclein and fibril formation rates by NMR and fluorescence.

Kang L, Janowska MK, Moriarty GM, Baum J.

PLoS One. 2013 Sep 18;8(9):e75018. doi: 10.1371/journal.pone.0075018. eCollection 2013.

5.

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

Greenbaum EA, Graves CL, Mishizen-Eberz AJ, Lupoli MA, Lynch DR, Englander SW, Axelsen PH, Giasson BI.

J Biol Chem. 2005 Mar 4;280(9):7800-7. Epub 2005 Jan 4.

6.

Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

Cohlberg JA, Li J, Uversky VN, Fink AL.

Biochemistry. 2002 Feb 5;41(5):1502-11.

PMID:
11814343
7.

Sequence determinants regulating fibrillation of human alpha-synuclein.

Koo HJ, Lee HJ, Im H.

Biochem Biophys Res Commun. 2008 Apr 11;368(3):772-8. doi: 10.1016/j.bbrc.2008.01.140. Epub 2008 Feb 7.

PMID:
18261982
8.

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.

Conway KA, Harper JD, Lansbury PT Jr.

Biochemistry. 2000 Mar 14;39(10):2552-63.

PMID:
10704204
9.

A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues.

Moriarty GM, Olson MP, Atieh TB, Janowska MK, Khare SD, Baum J.

J Biol Chem. 2017 Sep 29;292(39):16368-16379. doi: 10.1074/jbc.M117.780528. Epub 2017 Jul 14.

10.

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.

Rekas A, Adda CG, Andrew Aquilina J, Barnham KJ, Sunde M, Galatis D, Williamson NA, Masters CL, Anders RF, Robinson CV, Cappai R, Carver JA.

J Mol Biol. 2004 Jul 23;340(5):1167-83.

PMID:
15236975
11.

Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.

Koo HJ, Choi MY, Im H.

Biochem Biophys Res Commun. 2009 Aug 14;386(1):165-9. doi: 10.1016/j.bbrc.2009.06.002. Epub 2009 Jun 6.

PMID:
19501571
12.

The conformation and the aggregation kinetics of α-synuclein depend on the proline residues in its C-terminal region.

Meuvis J, Gerard M, Desender L, Baekelandt V, Engelborghs Y.

Biochemistry. 2010 Nov 2;49(43):9345-52. doi: 10.1021/bi1010927.

PMID:
20828147
13.

The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein.

Kim J, Harada R, Kobayashi M, Kobayashi N, Sode K.

Mol Neurodegener. 2010 May 20;5:20. doi: 10.1186/1750-1326-5-20.

14.

Investigation of alpha-synuclein fibril structure by site-directed spin labeling.

Chen M, Margittai M, Chen J, Langen R.

J Biol Chem. 2007 Aug 24;282(34):24970-9. Epub 2007 Jun 15.

15.

Role of different regions of alpha-synuclein in the assembly of fibrils.

Qin Z, Hu D, Han S, Hong DP, Fink AL.

Biochemistry. 2007 Nov 20;46(46):13322-30. Epub 2007 Oct 27.

PMID:
17963364
16.

Identification of the region responsible for fibril formation in the CAD domain of caspase-activated DNase.

Nakamura T, Kobayashi A, Hagihara Y, Takai T, Mine S, Yamazaki T, Yumoto N, Uegaki K.

J Biochem. 2005 Dec;138(6):815-9.

PMID:
16428311
17.

Modification of C Terminus Provides New Insights into the Mechanism of α-Synuclein Aggregation.

Afitska K, Fucikova A, Shvadchak VV, Yushchenko DA.

Biophys J. 2017 Nov 21;113(10):2182-2191. doi: 10.1016/j.bpj.2017.08.027. Epub 2017 Sep 20.

PMID:
28939194
18.

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro.

Murray IV, Giasson BI, Quinn SM, Koppaka V, Axelsen PH, Ischiropoulos H, Trojanowski JQ, Lee VM.

Biochemistry. 2003 Jul 22;42(28):8530-40.

PMID:
12859200
19.
20.

Supplemental Content

Support Center