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Items: 1 to 20 of 99

1.

ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.

Schou J, Tybjærg-Hansen A, Møller HJ, Nordestgaard BG, Frikke-Schmidt R.

Diabetes Care. 2012 Dec;35(12):2600-6. doi: 10.2337/dc12-0082. Epub 2012 Nov 8.

2.

Genetic variation in ABCG1 and risk of myocardial infarction and ischemic heart disease.

Schou J, Frikke-Schmidt R, Kardassis D, Thymiakou E, Nordestgaard BG, Jensen G, Grande P, Tybjærg-Hansen A.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):506-15. doi: 10.1161/ATVBAHA.111.234872. Epub 2011 Dec 8.

3.

Determinants of leukocyte adenosine triphosphate-binding cassette transporter G1 gene expression in type 2 diabetes mellitus.

Zhou H, Tan KC, Shiu SW, Wong Y.

Metabolism. 2008 Aug;57(8):1135-40. doi: 10.1016/j.metabol.2008.03.020.

PMID:
18640393
4.

Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease.

Frikke-Schmidt R, Nordestgaard BG, Stene MC, Sethi AA, Remaley AT, Schnohr P, Grande P, Tybjaerg-Hansen A.

JAMA. 2008 Jun 4;299(21):2524-32. doi: 10.1001/jama.299.21.2524.

PMID:
18523221
5.

Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.

Mauldin JP, Nagelin MH, Wojcik AJ, Srinivasan S, Skaflen MD, Ayers CR, McNamara CA, Hedrick CC.

Circulation. 2008 May 27;117(21):2785-92. doi: 10.1161/CIRCULATIONAHA.107.741314. Epub 2008 May 19.

6.

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells.

Mulay V, Wood P, Manetsch M, Darabi M, Cairns R, Hoque M, Chan KC, Reverter M, Alvarez-Guaita A, Rye KA, Rentero C, Heeren J, Enrich C, Grewal T.

PLoS One. 2013 Apr 25;8(4):e62667. doi: 10.1371/journal.pone.0062667. Print 2013.

7.

The expression of ATP-binding cassette transporters in hypertensive patients.

Xu M, Zhou H, Gu Q, Li C.

Hypertens Res. 2009 Jun;32(6):455-61. doi: 10.1038/hr.2009.46. Epub 2009 Apr 24.

PMID:
19390536
8.

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells.

Kappus MS, Murphy AJ, Abramowicz S, Ntonga V, Welch CL, Tall AR, Westerterp M.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):279-84. doi: 10.1161/ATVBAHA.113.302781. Epub 2013 Dec 5.

9.

Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.

Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K.

Atherosclerosis. 2007 Mar;191(1):11-21. Epub 2006 May 30.

PMID:
16730733
10.

Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.

Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Wellington CL, LütJohann D, Johnson JD, Brunham LR, Verchere CB, Hayden MR.

Diabetes. 2012 Mar;61(3):659-64. doi: 10.2337/db11-1341. Epub 2012 Feb 7.

11.

Ligation of RAGE with ligand S100B attenuates ABCA1 expression in monocytes.

Kumar P, Raghavan S, Shanmugam G, Shanmugam N.

Metabolism. 2013 Aug;62(8):1149-58. doi: 10.1016/j.metabol.2013.02.006. Epub 2013 Mar 22.

PMID:
23523156
12.
13.

Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.

Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.

Atherosclerosis. 2011 Nov;219(1):141-50. doi: 10.1016/j.atherosclerosis.2011.07.113. Epub 2011 Aug 4.

PMID:
21862012
14.

ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis.

Ye D, Lammers B, Zhao Y, Meurs I, Van Berkel TJ, Van Eck M.

Curr Drug Targets. 2011 May;12(5):647-60. Review.

PMID:
21039336
15.

Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages.

Ku CS, Park Y, Coleman SL, Lee J.

J Nutr Biochem. 2012 Oct;23(10):1271-6. doi: 10.1016/j.jnutbio.2011.07.007. Epub 2011 Dec 29.

PMID:
22209005
16.

ABCA1 and ABCG1 expression in the small intestine of type 2 diabetic rats.

Lou J, Zhou H, Li C, Hu L, Lu X, Li J, Yao H, Li W, Zhang X, Xu M.

Lab Med. 2014 Winter;45(1):17-24.

PMID:
24719980
17.

Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.

Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR.

Circulation. 2008 Oct 28;118(18):1837-47. doi: 10.1161/CIRCULATIONAHA.108.793869. Epub 2008 Oct 13.

18.

The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux.

Porsch-Ozcurumez M, Langmann T, Heimerl S, Borsukova H, Kaminski WE, Drobnik W, Honer C, Schumacher C, Schmitz G.

J Biol Chem. 2001 Apr 13;276(15):12427-33. Epub 2001 Jan 22.

19.

Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling.

Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfield FR, Tall AR.

Circ Res. 2011 Jan 21;108(2):194-200. doi: 10.1161/CIRCRESAHA.110.228619. Epub 2010 Dec 9.

20.

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Lipid Res. 2003 Sep;44(9):1728-36. Epub 2003 Jun 1.

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