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Items: 1 to 20 of 199

1.

LC-MS-MS determination and pharmacokinetic study of the novel anti-tumor candidate drug TEOA in rats.

Gu J, Ding G, Chen N, Zhang Z.

J Chromatogr Sci. 2013 Jul;51(6):496-501. doi: 10.1093/chromsci/bms176. Epub 2012 Nov 8.

PMID:
23139245
2.

Development and validation of liquid chromatography-tandem mass spectrometry method for quantification of a potential anticancer triterpene saponin from seeds of Nigella glandulifera in rat plasma: application to a pharmacokinetic study.

Hu X, Liu X, Gong M, Luan M, Zheng Y, Wu G, Shentu J, Zhang L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 15;967:156-61. doi: 10.1016/j.jchromb.2014.07.030. Epub 2014 Jul 27.

PMID:
25108106
3.
4.

Determination and pharmacokinetic study of the novel anti-tumor candidate drug DG-7 in rat plasma by liquid chromatography-tandem mass spectrometry.

Li J, Liu DD, Ke Y, Guo F, Ding XM, Wang SL, Chen Y, Liu HM, Su YQ, Nan YY.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 1;960:14-8. doi: 10.1016/j.jchromb.2014.04.010. Epub 2014 Apr 13.

PMID:
24780702
5.

Determination and pharmacokinetic study of two triterpenoid saponins in rat plasma after oral administration of the extract of Aralia elata leaves by UHPLC-ESI-MS/MS.

Wang Z, Wu Q, Meng Y, Sun Y, Wang Q, Yang C, Wang Q, Yang B, Kuang H.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:164-71. doi: 10.1016/j.jchromb.2015.01.036. Epub 2015 Feb 3.

PMID:
25687802
6.

Quantification of taraxasterol in rat plasma by LC/MS/MS: application to a pharmacokinetic study.

Zhang N, Pang L, Dong N, Xu D, Xu H.

Biomed Chromatogr. 2015 Nov;29(11):1643-9. doi: 10.1002/bmc.3473. Epub 2015 Apr 14.

PMID:
25873241
7.

Determination of isotoosendanin in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetics study.

Deng Z, Zhong H, Liu S, Cui S, Xie Y, Yao Q.

J Chromatogr Sci. 2013 Jan;51(1):82-6. doi: 10.1093/chromsci/bms110. Epub 2012 Jul 19.

PMID:
22815211
8.

Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of goserelin in rabbit plasma.

Kim MK, Lee TH, Suh JH, Eom HY, Min JW, Yeom H, Kim U, Jung HJ, Cha KH, Choi YS, Youm JR, Han SB.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 15;878(24):2235-42. doi: 10.1016/j.jchromb.2010.06.031. Epub 2010 Jul 1.

PMID:
20655813
9.

Development and validation of a highly rapid and sensitive LC-MS/MS method for determination of SZ-685C, an investigational marine anticancer agent, in rat plasma--application to a pharmacokinetic study in rats.

Chen JY, Wang XD, Zhong GP, Qin XL, Li JL, Huang ZY, Zhu X, Li MF, Huang M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2127-34. doi: 10.1016/j.jchromb.2011.05.049. Epub 2011 Jun 12.

PMID:
21703949
10.

Determination of chamaechromone in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study.

Lou Y, Hu H, Liu Y, Yu Q, Li L, Ping L, Yu L, Jiang H, Zeng S.

J Pharm Biomed Anal. 2011 Jul 15;55(5):1163-9. doi: 10.1016/j.jpba.2011.04.009. Epub 2011 Apr 15.

PMID:
21549539
11.

Development and validation of an LC-ESI/MS/MS method with precolumn derivatization for the determination of betulin in rat plasma.

Hu Z, Guo N, Wang Z, Liu Y, Wang Y, Ding W, Zhang D, Wang Y, Yan X.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Nov 15;939:38-44. doi: 10.1016/j.jchromb.2013.09.005. Epub 2013 Sep 10.

PMID:
24095874
12.

LC-MS/MS method for the determination of agomelatine in human plasma and its application to a pharmacokinetic study.

Wang X, Zhang D, Liu M, Zhao H, Du A, Meng L, Liu H.

Biomed Chromatogr. 2014 Feb;28(2):218-22. doi: 10.1002/bmc.3008. Epub 2013 Aug 5.

PMID:
23918681
13.

Development of a novel method for triterpenoidal saponins in rat plasma by solid-phase extraction and high-performance liquid chromatography tandem mass spectrometry.

Xu H, Ji X, Shi X, Du Y, Zhu H, Zhang L.

Anal Biochem. 2011 Dec 15;419(2):323-32. doi: 10.1016/j.ab.2011.08.045. Epub 2011 Sep 1.

PMID:
21925476
14.

Development and validation of an LC/MS/MS method for simultaneous determination of shionone and epi-friedelinol in rat plasma for pharmacokinetic study after oral administration of Aster tataricus extract.

Yin DF, Zhou K, Liu JT, Hu L, Liu Y, Deng J, Wang SP, Xiong Y, Zhong W.

Biomed Chromatogr. 2016 Jul;30(7):1112-7. doi: 10.1002/bmc.3658. Epub 2015 Dec 20.

PMID:
26581126
15.

Determination of HS270, a new histone deacetylase inhibitor, in rat plasma by LC-MS/MS--application to a preclinical pharmacokinetic study.

Zhong GP, Chen JY, Bi HC, Qin XL, Dai CL, Liu J, Chen X, Zeng GX, Huang ZY, Huang M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Nov 15;879(30):3452-8. doi: 10.1016/j.jchromb.2011.09.023. Epub 2011 Sep 18.

PMID:
21983196
16.

Quantitative determination of euphol in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.

Xie X, Li Y, Gao D, Zhang Y, Ren Y.

Biomed Chromatogr. 2014 Sep;28(9):1229-34. doi: 10.1002/bmc.3151.

PMID:
25237707
17.

LC-ESI-MS/MS analysis and pharmacokinetics of jolkinolide B, a potential antitumor active component isolated from Euphorbia fischeriana, in rat plasma.

Li Y, Liu XL, Cai ZG, Zhang SX.

Biomed Chromatogr. 2014 Feb;28(2):193-6. doi: 10.1002/bmc.3000. Epub 2013 Jul 19.

PMID:
23868721
18.

Simultaneous determination of six C21 steroids of Xiao-Ai-Ping injection in rat plasma by LC-MS/MS.

Zeng Q, Zhang F, Gao S, Sun L, Jiang B, Chen W.

Biomed Chromatogr. 2014 Feb;28(2):223-30. doi: 10.1002/bmc.3009. Epub 2013 Aug 28.

PMID:
24037806
19.

Simultaneous determination of esculin and its metabolite esculetin in rat plasma by LC-ESI-MS/MS and its application in pharmacokinetic study.

Li YY, Song YY, Liu CH, Huang XT, Zheng X, Li N, Xu ML, Mi SQ, Wang NS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:27-33. doi: 10.1016/j.jchromb.2012.08.027. Epub 2012 Sep 7.

PMID:
22999477
20.

Quantitative determination of odanacatib in human plasma using liquid-liquid extraction followed by liquid chromatography-tandem mass spectrometry analysis.

Sun L, Forni S, Schwartz MS, Breidinger S, Woolf EJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Feb 15;885-886:15-23. doi: 10.1016/j.jchromb.2011.12.004. Epub 2011 Dec 13.

PMID:
22230741

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