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Items: 1 to 20 of 97

1.

Increased fetal insulin concentrations for one week fail to improve insulin secretion or β-cell mass in fetal sheep with chronically reduced glucose supply.

Lavezzi JR, Thorn SR, O'Meara MC, LoTurco D, Brown LD, Hay WW Jr, Rozance PJ.

Am J Physiol Regul Integr Comp Physiol. 2013 Jan 1;304(1):R50-8. doi: 10.1152/ajpregu.00413.2012. Epub 2012 Nov 7.

2.

Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep.

Gadhia MM, Maliszewski AM, O'Meara MC, Thorn SR, Lavezzi JR, Limesand SW, Hay WW Jr, Brown LD, Rozance PJ.

Am J Physiol Endocrinol Metab. 2013 Feb 15;304(4):E352-62. doi: 10.1152/ajpendo.00377.2012. Epub 2012 Dec 4.

3.

A physiological increase in insulin suppresses gluconeogenic gene activation in fetal sheep with sustained hypoglycemia.

Thorn SR, Sekar SM, Lavezzi JR, O'Meara MC, Brown LD, Hay WW Jr, Rozance PJ.

Am J Physiol Regul Integr Comp Physiol. 2012 Oct 15;303(8):R861-9. doi: 10.1152/ajpregu.00331.2012. Epub 2012 Aug 29.

4.

Reductions in insulin concentrations and β-cell mass precede growth restriction in sheep fetuses with placental insufficiency.

Limesand SW, Rozance PJ, Macko AR, Anderson MJ, Kelly AC, Hay WW Jr.

Am J Physiol Endocrinol Metab. 2013 Mar 1;304(5):E516-23. doi: 10.1152/ajpendo.00435.2012. Epub 2012 Dec 31.

5.

Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic beta-cells.

Rozance PJ, Limesand SW, Zerbe GO, Hay WW Jr.

Am J Physiol Endocrinol Metab. 2007 May;292(5):E1256-64. Epub 2007 Jan 9.

6.

Glucose suppression of insulin secretion in chronically hyperglycemic fetal sheep.

Carver TD, Anderson SM, Aldoretta PA, Esler AL, Hay WW Jr.

Pediatr Res. 1995 Nov;38(5):754-62.

PMID:
8552445
7.

Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term.

Zhang L, Long NM, Hein SM, Ma Y, Nathanielsz PW, Ford SP.

Domest Anim Endocrinol. 2011 Jan;40(1):30-9. doi: 10.1016/j.domaniend.2010.08.004. Epub 2010 Sep 19.

8.

Characterization of glucose-insulin responsiveness and impact of fetal number and sex difference on insulin response in the sheep fetus.

Green AS, Macko AR, Rozance PJ, Yates DT, Chen X, Hay WW Jr, Limesand SW.

Am J Physiol Endocrinol Metab. 2011 May;300(5):E817-23. doi: 10.1152/ajpendo.00572.2010. Epub 2011 Feb 22.

9.

Maternal and fetal growth, body composition, endocrinology, and metabolic status in undernourished adolescent sheep.

Luther J, Aitken R, Milne J, Matsuzaki M, Reynolds L, Redmer D, Wallace J.

Biol Reprod. 2007 Aug;77(2):343-50. Epub 2007 May 2.

10.

Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction.

Rozance PJ, Limesand SW, Barry JS, Brown LD, Hay WW Jr.

Pediatr Res. 2009 Jan;65(1):72-8. doi: 10.1203/PDR.0b013e318189358c.

11.

Increased adrenergic signaling is responsible for decreased glucose-stimulated insulin secretion in the chronically hyperinsulinemic ovine fetus.

Andrews SE, Brown LD, Thorn SR, Limesand SW, Davis M, Hay WW Jr, Rozance PJ.

Endocrinology. 2015 Jan;156(1):367-76. doi: 10.1210/en.2014-1393.

12.

Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep.

Wallace JM, Milne JS, Aitken RP, Hay WW Jr.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1233-41. Epub 2007 Aug 21.

13.

The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep.

Burrage DM, Braddick L, Cleal JK, Costello P, Noakes DE, Hanson MA, Green LR.

J Physiol. 2009 Feb 1;587(3):611-24. doi: 10.1113/jphysiol.2008.165944. Epub 2008 Dec 22.

14.

Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep.

Chen X, Green AS, Macko AR, Yates DT, Kelly AC, Limesand SW.

Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E58-64. doi: 10.1152/ajpendo.00517.2013. Epub 2013 Nov 19.

15.

Impairment of rat fetal beta-cell development by maternal exposure to dexamethasone during different time-windows.

Dumortier O, Theys N, Ahn MT, Remacle C, Reusens B.

PLoS One. 2011;6(10):e25576. doi: 10.1371/journal.pone.0025576. Epub 2011 Oct 3.

16.
17.

Maternal obesity accelerates fetal pancreatic beta-cell but not alpha-cell development in sheep: prenatal consequences.

Ford SP, Zhang L, Zhu M, Miller MM, Smith DT, Hess BW, Moss GE, Nathanielsz PW, Nijland MJ.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R835-43. doi: 10.1152/ajpregu.00072.2009. Epub 2009 Jul 15.

18.

Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction.

Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW.

Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E770-8. doi: 10.1152/ajpendo.00494.2009. Epub 2010 Jan 19.

19.

Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth.

Owens JA, Gatford KL, De Blasio MJ, Edwards LJ, McMillen IC, Fowden AL.

J Physiol. 2007 Nov 1;584(Pt 3):935-49. Epub 2007 Aug 30.

20.

Post-hepatic insulin secretion in the fetal lamb.

Creswell JS, Susa JB, Cowett RM, Tenenbaum DG, Oh W.

Pediatr Res. 1983 Sep;17(9):758-62.

PMID:
6353345
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