Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 69

1.

Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site.

Alfadhli A, McNett H, Eccles J, Tsagli S, Noviello C, Sloan R, López CS, Peyton DH, Barklis E.

J Biol Chem. 2013 Jan 4;288(1):666-76. doi: 10.1074/jbc.M112.399865. Epub 2012 Nov 7.

2.

HIV-1 matrix protein binding to RNA.

Alfadhli A, McNett H, Tsagli S, Bächinger HP, Peyton DH, Barklis E.

J Mol Biol. 2011 Jul 22;410(4):653-66. doi: 10.1016/j.jmb.2011.04.063.

3.

The roles of lipids and nucleic acids in HIV-1 assembly.

Alfadhli A, Barklis E.

Front Microbiol. 2014 May 28;5:253. doi: 10.3389/fmicb.2014.00253. eCollection 2014. Review.

4.

Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids.

Alfadhli A, Still A, Barklis E.

J Virol. 2009 Dec;83(23):12196-203. doi: 10.1128/JVI.01197-09. Epub 2009 Sep 23.

5.

Analysis of HIV-1 Matrix-Envelope Cytoplasmic Tail Interactions.

Alfadhli A, Staubus AO, Tedbury PR, Novikova M, Freed EO, Barklis E.

J Virol. 2019 Oct 15;93(21). pii: e01079-19. doi: 10.1128/JVI.01079-19. Print 2019 Nov 1.

PMID:
31375589
6.

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate.

Alfadhli A, Barklis RL, Barklis E.

Virology. 2009 May 10;387(2):466-72. doi: 10.1016/j.virol.2009.02.048. Epub 2009 Mar 27.

7.

Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.

Vlach J, Saad JS.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3525-30. doi: 10.1073/pnas.1216655110. Epub 2013 Feb 11.

8.

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.

Saad JS, Miller J, Tai J, Kim A, Ghanam RH, Summers MF.

Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11364-9. Epub 2006 Jul 13.

9.
10.

Identification of a small-molecule inhibitor of HIV-1 assembly that targets the phosphatidylinositol (4,5)-bisphosphate binding site of the HIV-1 matrix protein.

Zentner I, Sierra LJ, Fraser AK, Maciunas L, Mankowski MK, Vinnik A, Fedichev P, Ptak RG, Martín-García J, Cocklin S.

ChemMedChem. 2013 Mar;8(3):426-32. doi: 10.1002/cmdc.201200577. Epub 2013 Jan 29.

11.

Relationships between MA-RNA Binding in Cells and Suppression of HIV-1 Gag Mislocalization to Intracellular Membranes.

Thornhill D, Olety B, Ono A.

J Virol. 2019 Nov 13;93(23). pii: e00756-19. doi: 10.1128/JVI.00756-19. Print 2019 Dec 1.

PMID:
31511376
12.

Point mutations in the HIV-1 matrix protein turn off the myristyl switch.

Saad JS, Loeliger E, Luncsford P, Liriano M, Tai J, Kim A, Miller J, Joshi A, Freed EO, Summers MF.

J Mol Biol. 2007 Feb 16;366(2):574-85. Epub 2006 Dec 1.

13.

Membrane-induced alterations in HIV-1 Gag and matrix protein-protein interactions.

Scarlata S, Ehrlich LS, Carter CA.

J Mol Biol. 1998 Mar 27;277(2):161-9.

PMID:
9514761
14.

Retrovirus-specific differences in matrix and nucleocapsid protein-nucleic acid interactions: implications for genomic RNA packaging.

Sun M, Grigsby IF, Gorelick RJ, Mansky LM, Musier-Forsyth K.

J Virol. 2014 Jan;88(2):1271-80. doi: 10.1128/JVI.02151-13. Epub 2013 Nov 13.

15.
16.

Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain.

Chukkapalli V, Oh SJ, Ono A.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1600-5. doi: 10.1073/pnas.0908661107. Epub 2010 Jan 4.

17.

Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure.

Ghanam RH, Fernandez TF, Fledderman EL, Saad JS.

J Biol Chem. 2010 Dec 31;285(53):41911-20. doi: 10.1074/jbc.M110.179093. Epub 2010 Oct 18.

18.

Effect of multimerization on membrane association of Rous sarcoma virus and HIV-1 matrix domain proteins.

Dick RA, Kamynina E, Vogt VM.

J Virol. 2013 Dec;87(24):13598-608. doi: 10.1128/JVI.01659-13. Epub 2013 Oct 9.

19.
20.

Targeting of murine leukemia virus gag to the plasma membrane is mediated by PI(4,5)P2/PS and a polybasic region in the matrix.

Hamard-Peron E, Juillard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D.

J Virol. 2010 Jan;84(1):503-15. doi: 10.1128/JVI.01134-09.

Supplemental Content

Support Center