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Items: 1 to 20 of 82

1.

Early postnatal lead exposure induces tau phosphorylation in the brain of young rats.

Rahman A, Khan KM, Al-Khaledi G, Khan I, Attur S.

Acta Biol Hung. 2012 Dec;63(4):411-25. doi: 10.1556/ABiol.63.2012.4.1.

PMID:
23134599
2.

Over activation of hippocampal serine/threonine protein phosphatases PP1 and PP2A is involved in lead-induced deficits in learning and memory in young rats.

Rahman A, Khan KM, Al-Khaledi G, Khan I, Al-Shemary T.

Neurotoxicology. 2012 Jun;33(3):370-83. doi: 10.1016/j.neuro.2012.02.014. Epub 2012 Mar 1.

PMID:
22387731
3.

Lead dysregulates serine/threonine protein phosphatases in human neurons.

Rahman A, Brew BJ, Guillemin GJ.

Neurochem Res. 2011 Feb;36(2):195-204. doi: 10.1007/s11064-010-0300-6. Epub 2010 Nov 4.

4.

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.

Liu F, Grundke-Iqbal I, Iqbal K, Gong CX.

Eur J Neurosci. 2005 Oct;22(8):1942-50.

PMID:
16262633
5.

Perinatal exposure to lead (Pb) promotes Tau phosphorylation in the rat brain in a GSK-3β and CDK5 dependent manner: Relevance to neurological disorders.

Gąssowska M, Baranowska-Bosiacka I, Moczydłowska J, Tarnowski M, Pilutin A, Gutowska I, Strużyńska L, Chlubek D, Adamczyk A.

Toxicology. 2016 Mar 10;347-349:17-28. doi: 10.1016/j.tox.2016.03.002. Epub 2016 Mar 21.

PMID:
27012722
6.

Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats.

Wang X, Blanchard J, Tung YC, Grundke-Iqbal I, Iqbal K.

J Alzheimers Dis. 2015;45(2):423-35. doi: 10.3233/JAD-142403.

PMID:
25589718
7.
8.

Tau hyperphosphorylation is associated with spatial learning and memory after exposure to benzo[a]pyrene in SD rats.

Nie J, Duan L, Yan Z, Niu Q.

Neurotox Res. 2013 Nov;24(4):461-71. doi: 10.1007/s12640-013-9387-2. Epub 2013 Mar 19.

PMID:
23508864
9.

Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome.

Liang Z, Liu F, Iqbal K, Grundke-Iqbal I, Wegiel J, Gong CX.

J Alzheimers Dis. 2008 Apr;13(3):295-302.

10.

Effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the C57BL/6 mouse hippocampus at different life stages.

Liu F, Xue Z, Li N, Huang H, Ying Y, Li J, Wang L, Li W.

J Trace Elem Med Biol. 2014 Apr;28(2):227-32. doi: 10.1016/j.jtemb.2014.01.002. Epub 2014 Jan 29.

PMID:
24582137
11.

Increased tau phosphorylation and beta amyloid in the hipocampus of mouse pups by early life lead exposure.

Li N, Yu ZL, Wang L, Zheng YT, Jia JX, Wang Q, Zhu MJ, Liu XL, Xia X, Li WJ.

Acta Biol Hung. 2010 Jun;61(2):123-34. doi: 10.1556/ABiol.61.2010.2.1.

PMID:
20519167
12.

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

Mawal-Dewan M, Henley J, Van de Voorde A, Trojanowski JQ, Lee VM.

J Biol Chem. 1994 Dec 9;269(49):30981-7.

13.

Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam.

Arif M, Kazim SF, Grundke-Iqbal I, Garruto RM, Iqbal K.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1144-9. doi: 10.1073/pnas.1322614111. Epub 2014 Jan 6.

14.

Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model.

Corcoran NM, Martin D, Hutter-Paier B, Windisch M, Nguyen T, Nheu L, Sundstrom LE, Costello AJ, Hovens CM.

J Clin Neurosci. 2010 Aug;17(8):1025-33. doi: 10.1016/j.jocn.2010.04.020. Epub 2010 May 26.

PMID:
20537899
15.

Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease.

Liu F, Iqbal K, Grundke-Iqbal I, Rossie S, Gong CX.

J Biol Chem. 2005 Jan 21;280(3):1790-6. Epub 2004 Nov 15.

16.

(Val⁸) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains.

Li L, Zhang ZF, Holscher C, Gao C, Jiang YH, Liu YZ.

Eur J Pharmacol. 2012 Jan 15;674(2-3):280-6. doi: 10.1016/j.ejphar.2011.11.005. Epub 2011 Nov 12.

PMID:
22115895
17.
18.

Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation.

Xiong Y, Jing XP, Zhou XW, Wang XL, Yang Y, Sun XY, Qiu M, Cao FY, Lu YM, Liu R, Wang JZ.

Neurobiol Aging. 2013 Mar;34(3):745-56. doi: 10.1016/j.neurobiolaging.2012.07.003. Epub 2012 Aug 11.

PMID:
22892311
19.
20.

Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5.

Gong CX, Liu F, Wu G, Rossie S, Wegiel J, Li L, Grundke-Iqbal I, Iqbal K.

J Neurochem. 2004 Jan;88(2):298-310.

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