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Items: 1 to 20 of 101

1.

2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines.

Marcilla-Etxenike A, Martín ML, Noguera-Salvà MA, García-Verdugo JM, Soriano-Navarro M, Dey I, Escribá PV, Busquets X.

PLoS One. 2012;7(10):e48235. doi: 10.1371/journal.pone.0048235. Epub 2012 Oct 25.

2.

2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.

Terés S, Lladó V, Higuera M, Barceló-Coblijn G, Martin ML, Noguera-Salvà MA, Marcilla-Etxenike A, García-Verdugo JM, Soriano-Navarro M, Saus C, Gómez-Pinedo U, Busquets X, Escribá PV.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8489-94. doi: 10.1073/pnas.1118349109. Epub 2012 May 14.

3.

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.

Barceló-Coblijn G, Martin ML, de Almeida RF, Noguera-Salvà MA, Marcilla-Etxenike A, Guardiola-Serrano F, Lüth A, Kleuser B, Halver JE, Escribá PV.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19569-74. doi: 10.1073/pnas.1115484108. Epub 2011 Nov 21.

4.

The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.

Martin ML, Barceló-Coblijn G, de Almeida RF, Noguera-Salvà MA, Terés S, Higuera M, Liebisch G, Schmitz G, Busquets X, Escribá PV.

Biochim Biophys Acta. 2013 May;1828(5):1405-13. doi: 10.1016/j.bbamem.2013.01.013. Epub 2013 Jan 27.

5.

Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells.

Terés S, Lladó V, Higuera M, Barceló-Coblijn G, Martin ML, Noguera-Salvà MA, Marcilla-Etxenike A, García-Verdugo JM, Soriano-Navarro M, Saus C, Gómez-Pinedo U, Busquets X, Escribá PV.

Autophagy. 2012 Oct;8(10):1542-4. doi: 10.4161/auto.21341. Epub 2012 Aug 15.

6.

The neuro-steroid, 5-androstene 3β,17α diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2α signaling in malignant glioma cells and transformed fibroblasts.

Jia W, Loria RM, Park MA, Yacoub A, Dent P, Graf MR.

Int J Biochem Cell Biol. 2010 Dec;42(12):2019-29. doi: 10.1016/j.biocel.2010.09.003. Epub 2010 Sep 18.

PMID:
20851775
7.

Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells.

Hwang MS, Baek WK.

Biochem Biophys Res Commun. 2010 Aug 13;399(1):111-6. doi: 10.1016/j.bbrc.2010.07.050. Epub 2010 Jul 17.

PMID:
20643103
8.

Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.

Piotto S, Concilio S, Bianchino E, Iannelli P, López DJ, Terés S, Ibarguren M, Barceló-Coblijn G, Martin ML, Guardiola-Serrano F, Alonso-Sande M, Funari SS, Busquets X, Escribá PV.

Biochim Biophys Acta. 2014 Jun;1838(6):1628-37. doi: 10.1016/j.bbamem.2013.12.023. Epub 2014 Jan 9.

9.

Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death.

Liu WT, Huang CY, Lu IC, Gean PW.

Neuro Oncol. 2013 Sep;15(9):1127-41. doi: 10.1093/neuonc/not073. Epub 2013 Jun 20.

10.

Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell death.

Ciechomska IA, Gabrusiewicz K, Szczepankiewicz AA, Kaminska B.

Oncogene. 2013 Mar 21;32(12):1518-29. doi: 10.1038/onc.2012.174. Epub 2012 May 14.

PMID:
22580614
12.

Down-regulation of 14-3-3β exerts anti-cancer effects through inducing ER stress in human glioma U87 cells: Involvement of CHOP-Wnt pathway.

Cao L, Lei H, Chang MZ, Liu ZQ, Bie XH.

Biochem Biophys Res Commun. 2015 Jul 10;462(4):389-95. doi: 10.1016/j.bbrc.2015.05.003. Epub 2015 May 14.

PMID:
25982477
13.

Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines.

Galluzzi L, De Santi M, Crinelli R, De Marco C, Zaffaroni N, Duranti A, Brandi G, Magnani M.

PLoS One. 2012;7(8):e43249. doi: 10.1371/journal.pone.0043249. Epub 2012 Aug 14.

14.

Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.

Chu PM, Chen LH, Chen MT, Ma HI, Su TL, Hsieh PC, Chien CS, Jiang BH, Chen YC, Lin YH, Shih YH, Tu PH, Chiou SH.

Cancer Chemother Pharmacol. 2012 Mar;69(3):621-33. doi: 10.1007/s00280-011-1747-0. Epub 2011 Sep 27.

PMID:
21947203
15.

The BH3 mimetic S1 induces autophagy through ER stress and disruption of Bcl-2/Beclin 1 interaction in human glioma U251 cells.

Zhong JT, Xu Y, Yi HW, Su J, Yu HM, Xiang XY, Li XN, Zhang ZC, Sun LK.

Cancer Lett. 2012 Oct 28;323(2):180-7. doi: 10.1016/j.canlet.2012.04.009. Epub 2012 May 8.

PMID:
22579788
16.

Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells.

Zhang R, Wang R, Chen Q, Chang H.

Mol Med Rep. 2015 Aug;12(2):1727-32. doi: 10.3892/mmr.2015.3588. Epub 2015 Apr 1.

17.

Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.

Cattaneo M, Baronchelli S, Schiffer D, Mellai M, Caldera V, Saccani GJ, Dalpra L, Daga A, Orlandi R, DeBlasio P, Biunno I.

J Biol Chem. 2014 Jan 31;289(5):2826-38. doi: 10.1074/jbc.M113.527754. Epub 2013 Dec 5.

18.

TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling.

Sakabe I, Hu R, Jin L, Clarke R, Kasid UN.

Breast Cancer Res Treat. 2015 Sep;153(2):285-97. doi: 10.1007/s10549-015-3536-7. Epub 2015 Aug 13.

19.

ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine.

Pallichankandy S, Rahman A, Thayyullathil F, Galadari S.

Free Radic Biol Med. 2015 Dec;89:708-20. doi: 10.1016/j.freeradbiomed.2015.10.404. Epub 2015 Nov 4.

PMID:
26472194
20.

Oncogenic BRAF inhibitor UAI-201 induces cell cycle arrest and autophagy in BRAF mutant glioma cells.

Ahn JH, Lee YW, Ahn SK, Lee M.

Life Sci. 2014 May 28;104(1-2):38-46. doi: 10.1016/j.lfs.2014.03.026. Epub 2014 Apr 8.

PMID:
24721513

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