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Items: 1 to 20 of 109

1.

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.

Amambua-Ngwa A, Tetteh KK, Manske M, Gomez-Escobar N, Stewart LB, Deerhake ME, Cheeseman IH, Newbold CI, Holder AA, Knuepfer E, Janha O, Jallow M, Campino S, Macinnis B, Kwiatkowski DP, Conway DJ.

PLoS Genet. 2012;8(11):e1002992. doi: 10.1371/journal.pgen.1002992. Epub 2012 Nov 1.

2.

Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum.

Ochola LI, Tetteh KK, Stewart LB, Riitho V, Marsh K, Conway DJ.

Mol Biol Evol. 2010 Oct;27(10):2344-51. doi: 10.1093/molbev/msq119. Epub 2010 May 9.

3.

Temporal expression and localization patterns of variant surface antigens in clinical Plasmodium falciparum isolates during erythrocyte schizogony.

Bachmann A, Petter M, Tilly AK, Biller L, Uliczka KA, Duffy MF, Tannich E, Bruchhaus I.

PLoS One. 2012;7(11):e49540. doi: 10.1371/journal.pone.0049540. Epub 2012 Nov 15.

4.

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity.

Mobegi VA, Duffy CW, Amambua-Ngwa A, Loua KM, Laman E, Nwakanma DC, MacInnis B, Aspeling-Jones H, Murray L, Clark TG, Kwiatkowski DP, Conway DJ.

Mol Biol Evol. 2014 Jun;31(6):1490-9. doi: 10.1093/molbev/msu106. Epub 2014 Mar 18.

5.

Prospective identification of malaria parasite genes under balancing selection.

Tetteh KK, Stewart LB, Ochola LI, Amambua-Ngwa A, Thomas AW, Marsh K, Weedall GD, Conway DJ.

PLoS One. 2009;4(5):e5568. doi: 10.1371/journal.pone.0005568. Epub 2009 May 15.

6.

Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection.

Reeder JC, Wapling J, Mueller I, Siba PM, Barry AE.

Malar J. 2011 May 14;10:126. doi: 10.1186/1475-2875-10-126.

7.

Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection.

Polley SD, Tetteh KK, Lloyd JM, Akpogheneta OJ, Greenwood BM, Bojang KA, Conway DJ.

J Infect Dis. 2007 Jan 15;195(2):279-87. Epub 2006 Dec 13.

PMID:
17191173
8.

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients.

Robinson T, Campino SG, Auburn S, Assefa SA, Polley SD, Manske M, MacInnis B, Rockett KA, Maslen GL, Sanders M, Quail MA, Chiodini PL, Kwiatkowski DP, Clark TG, Sutherland CJ.

PLoS One. 2011;6(8):e23204. doi: 10.1371/journal.pone.0023204. Epub 2011 Aug 11.

9.

Imputation-based population genetics analysis of Plasmodium falciparum malaria parasites.

Samad H, Coll F, Preston MD, Ocholla H, Fairhurst RM, Clark TG.

PLoS Genet. 2015 Apr 30;11(4):e1005131. doi: 10.1371/journal.pgen.1005131. eCollection 2015 Apr. Erratum in: PLoS Genet. 2016 Aug;12(8):e1006300.

10.

Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens.

Weedall GD, Preston BM, Thomas AW, Sutherland CJ, Conway DJ.

Int J Parasitol. 2007 Jan;37(1):77-85. Epub 2006 Sep 25.

PMID:
17046771
11.

Characterization of the repertoire diversity of the Plasmodium falciparum stevor multigene family in laboratory and field isolates.

Blythe JE, Niang M, Marsh K, Holder AA, Langhorne J, Preiser PR.

Malar J. 2009 Jun 26;8:140. doi: 10.1186/1475-2875-8-140.

12.

Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA5.

Tanabe K, Arisue N, Palacpac NM, Yagi M, Tougan T, Honma H, Ferreira MU, Färnert A, Björkman A, Kaneko A, Nakamura M, Hirayama K, Mita T, Horii T.

Vaccine. 2012 Feb 21;30(9):1583-93. doi: 10.1016/j.vaccine.2011.12.124. Epub 2012 Jan 9.

PMID:
22230587
13.

RSpred, a set of Hidden Markov Models to detect and classify the RIFIN and STEVOR proteins of Plasmodium falciparum.

Joannin N, Kallberg Y, Wahlgren M, Persson B.

BMC Genomics. 2011 Feb 18;12:119. doi: 10.1186/1471-2164-12-119.

14.

Contrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparum.

Barry AE, Schultz L, Buckee CO, Reeder JC.

PLoS One. 2009 Dec 30;4(12):e8497. doi: 10.1371/journal.pone.0008497.

15.

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity.

Duffy CW, Assefa SA, Abugri J, Amoako N, Owusu-Agyei S, Anyorigiya T, MacInnis B, Kwiatkowski DP, Conway DJ, Awandare GA.

BMC Genomics. 2015 Jul 16;16:527. doi: 10.1186/s12864-015-1746-3.

16.

Hypervariability within the Rifin, Stevor and Pfmc-2TM superfamilies in Plasmodium falciparum.

Lavazec C, Sanyal S, Templeton TJ.

Nucleic Acids Res. 2006;34(22):6696-707. Epub 2006 Dec 5.

17.

Patterns of polymorphism in genomic regions flanking three highly polymorphic surface antigens in Plasmodium falciparum.

Amodu OK, Hartl DL, Roy SW.

Mol Biochem Parasitol. 2008 May;159(1):1-6. doi: 10.1016/j.molbiopara.2007.12.004. Epub 2007 Dec 15.

PMID:
18291540
18.

Within-population genetic diversity of Plasmodium falciparum vaccine candidate antigens reveals geographic distance from a Central sub-Saharan African origin.

Tanabe K, Mita T, Palacpac NM, Arisue N, Tougan T, Kawai S, Jombart T, Kobayashi F, Horii T.

Vaccine. 2013 Feb 18;31(9):1334-9. doi: 10.1016/j.vaccine.2012.12.039. Epub 2013 Jan 4.

PMID:
23295064
20.

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