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Items: 1 to 20 of 117

1.

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.

Shirasaka Y, Shichiri M, Mori T, Nakanishi T, Tamai I.

J Pharm Sci. 2013 Jan;102(1):280-8. doi: 10.1002/jps.23357. Epub 2012 Nov 6.

PMID:
23132664
2.

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.

Shirasaka Y, Shichiri M, Mori T, Nakanishi T, Tamai I.

J Pharm Sci. 2013 Sep;102(9):3418-26. doi: 10.1002/jps.23653. Epub 2013 Jun 21.

PMID:
23794501
3.

Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.

Shirasaka Y, Shichiri M, Murata Y, Mori T, Nakanishi T, Tamai I.

Drug Metab Dispos. 2013 Mar;41(3):615-21. doi: 10.1124/dmd.112.049635. Epub 2012 Dec 21.

4.

Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y.

Drug Metab Dispos. 2005 Apr;33(4):518-23. Epub 2005 Jan 7.

5.

Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.

Shirasaka Y, Mori T, Murata Y, Nakanishi T, Tamai I.

Pharm Res. 2014 Aug;31(8):2035-43. doi: 10.1007/s11095-014-1305-7. Epub 2014 Feb 19.

PMID:
24549825
6.

A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect".

Won CS, Lan T, Vandermolen KM, Dawson PA, Oberlies NH, Widmer WW, Scarlett YV, Paine MF.

J Clin Pharmacol. 2013 Sep;53(9):982-90. doi: 10.1002/jcph.136. Epub 2013 Jul 23.

7.

Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.

Li P, Callery PS, Gan LS, Balani SK.

Drug Metab Dispos. 2007 Jul;35(7):1203-8. Epub 2007 Apr 23.

8.

Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat.

Shirasaka Y, Kuraoka E, Spahn-Langguth H, Nakanishi T, Langguth P, Tamai I.

J Pharmacol Exp Ther. 2010 Jan;332(1):181-9. doi: 10.1124/jpet.109.159756. Epub 2009 Sep 24.

9.

Effects of the flavanone combination hesperetin-naringenin, and orange and grapefruit juices, on airway inflammation and remodeling in a murine asthma model.

Seyedrezazadeh E, Kolahian S, Shahbazfar AA, Ansarin K, Pour Moghaddam M, Sakhinia M, Sakhinia E, Vafa M.

Phytother Res. 2015 Apr;29(4):591-8. doi: 10.1002/ptr.5292. Epub 2015 Jan 15.

PMID:
25640915
10.

Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

Bailey DG, Dresser GK, Leake BF, Kim RB.

Clin Pharmacol Ther. 2007 Apr;81(4):495-502. Epub 2007 Feb 14.

PMID:
17301733
11.

Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices.

So FV, Guthrie N, Chambers AF, Moussa M, Carroll KK.

Nutr Cancer. 1996;26(2):167-81.

PMID:
8875554
12.

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB.

Clin Pharmacol Ther. 2002 Jan;71(1):11-20.

PMID:
11823753
13.

Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein.

Shirasaka Y, Suzuki K, Nakanishi T, Tamai I.

J Pharm Sci. 2011 Sep;100(9):3843-53. doi: 10.1002/jps.22586. Epub 2011 Apr 24.

PMID:
21520088
14.

Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites.

Shirasaka Y, Mori T, Shichiri M, Nakanishi T, Tamai I.

Drug Metab Pharmacokinet. 2012;27(3):360-4. Epub 2011 Dec 27.

15.

Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers.

Akamine Y, Miura M, Komori H, Saito S, Kusuhara H, Tamai I, Ieiri I, Uno T, Yasui-Furukori N.

Eur J Clin Pharmacol. 2014 Sep;70(9):1087-95. doi: 10.1007/s00228-014-1705-y. Epub 2014 Jun 7.

PMID:
24903351
16.

Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.

Fujita D, Saito Y, Nakanishi T, Tamai I.

Drug Metab Dispos. 2016 Jan;44(1):1-7. doi: 10.1124/dmd.115.066712. Epub 2015 Nov 2.

PMID:
26526067
17.

The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion.

Akamine Y, Miura M, Komori H, Tamai I, Ieiri I, Yasui-Furukori N, Uno T.

Drug Metab Pharmacokinet. 2015 Oct;30(5):352-7. doi: 10.1016/j.dmpk.2015.06.005. Epub 2015 Jun 26.

PMID:
26213156
18.

[Flavonoids--bioactive compounds in fruits juice].

Harapu CD, Miron A, Cuciureanu M, Cuciureanu R.

Rev Med Chir Soc Med Nat Iasi. 2010 Oct-Dec;114(4):1209-14. Romanian.

PMID:
21500482
19.

Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.

Rebello S, Zhao S, Hariry S, Dahlke M, Alexander N, Vapurcuyan A, Hanna I, Jarugula V.

Eur J Clin Pharmacol. 2012 May;68(5):697-708. doi: 10.1007/s00228-011-1167-4. Epub 2011 Nov 29.

PMID:
22124880
20.

Fruit juice inhibition of uptake transport: a new type of food-drug interaction.

Bailey DG.

Br J Clin Pharmacol. 2010 Nov;70(5):645-55. doi: 10.1111/j.1365-2125.2010.03722.x. Review.

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