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Items: 1 to 20 of 107

1.

Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies.

Carbone CJ, Zheng H, Bhattacharya S, Lewis JR, Reiter AM, Henthorn P, Zhang ZY, Baker DP, Ukkiramapandian R, Bence KK, Fuchs SY.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19226-31. doi: 10.1073/pnas.1211491109. Epub 2012 Nov 5.

2.

Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.

Kumar KG, Barriere H, Carbone CJ, Liu J, Swaminathan G, Xu P, Li Y, Baker DP, Peng J, Lukacs GL, Fuchs SY.

J Cell Biol. 2007 Dec 3;179(5):935-50.

3.

Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2.

Zheng H, Qian J, Varghese B, Baker DP, Fuchs S.

Mol Cell Biol. 2011 Feb;31(4):710-20. doi: 10.1128/MCB.01154-10. Epub 2010 Dec 20.

4.

Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor.

Bhattacharya S, Qian J, Tzimas C, Baker DP, Koumenis C, Diehl JA, Fuchs SY.

J Biol Chem. 2011 Jun 24;286(25):22069-76. doi: 10.1074/jbc.M111.238766. Epub 2011 May 3.

5.

Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor.

Bhattacharya S, HuangFu WC, Liu J, Veeranki S, Baker DP, Koumenis C, Diehl JA, Fuchs SY.

J Biol Chem. 2010 Jan 22;285(4):2318-25. doi: 10.1074/jbc.M109.071498. Epub 2009 Nov 30.

6.

Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif.

Kumar KG, Varghese B, Banerjee A, Baker DP, Constantinescu SN, Pellegrini S, Fuchs SY.

J Biol Chem. 2008 Jul 4;283(27):18566-72. doi: 10.1074/jbc.M800991200. Epub 2008 May 12.

7.

Localization of a receptor nonapeptide with a possible role in the binding of the type I interferons.

Eid P, Langer JA, Bailly G, Lejealle R, Guymarho J, Tovey MG.

Eur Cytokine Netw. 2000 Dec;11(4):560-73.

8.

Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S.

PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. eCollection 2015.

9.

Identification of residues of the IFNAR1 chain of the type I human interferon receptor critical for ligand binding and biological activity.

Cajean-Feroldi C, Nosal F, Nardeux PC, Gallet X, Guymarho J, Baychelier F, Sempé P, Tovey MG, Escary JL, Eid P.

Biochemistry. 2004 Oct 5;43(39):12498-512.

PMID:
15449939
10.
11.

Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.

Claudinon J, Gonnord P, Beslard E, Marchetti M, Mitchell K, Boularan C, Johannes L, Eid P, Lamaze C.

J Biol Chem. 2009 Sep 4;284(36):24328-40. doi: 10.1074/jbc.M109.021915. Epub 2009 Jun 26.

12.
13.

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1.

de Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Rossjohn J, Hertzog PJ.

Nat Immunol. 2013 Sep;14(9):901-7. doi: 10.1038/ni.2667. Epub 2013 Jul 21.

PMID:
23872679
14.

Ligand-independent pathway that controls stability of interferon alpha receptor.

Liu J, Plotnikov A, Banerjee A, Suresh Kumar KG, Ragimbeau J, Marijanovic Z, Baker DP, Pellegrini S, Fuchs SY.

Biochem Biophys Res Commun. 2008 Mar 7;367(2):388-93. doi: 10.1016/j.bbrc.2007.12.137. Epub 2007 Dec 31.

15.

Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.

Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, Leu NA, Yau PM, Donald RG, Weiss MJ, Baker DP, McLaughlin KJ, Scott P, Fuchs SY.

Mol Cell Biol. 2009 Dec;29(24):6401-12. doi: 10.1128/MCB.00478-09. Epub 2009 Oct 5.

16.

The role of protein-tyrosine phosphatase 1B in integrin signaling.

Liang F, Lee SY, Liang J, Lawrence DS, Zhang ZY.

J Biol Chem. 2005 Jul 1;280(26):24857-63. Epub 2005 May 2.

17.
18.

Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling.

Ozek C, Kanoski SE, Zhang ZY, Grill HJ, Bence KK.

J Biol Chem. 2014 Nov 14;289(46):31682-92. doi: 10.1074/jbc.M114.603621. Epub 2014 Oct 6.

19.

Association of protein tyrosine phosphatases (PTPs)-1B with c-Met receptor and modulation of corneal epithelial wound healing.

Kakazu A, Sharma G, Bazan HE.

Invest Ophthalmol Vis Sci. 2008 Jul;49(7):2927-35. doi: 10.1167/iovs.07-0709.

20.

Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation.

Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG.

J Biol Chem. 2013 Jun 14;288(24):17360-71. doi: 10.1074/jbc.M112.441469. Epub 2013 May 2.

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