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Items: 1 to 20 of 369

1.

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission.

Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson KC, Lambert LE, Long C, Austin CP, Wu Y, Su XZ.

Antimicrob Agents Chemother. 2013 Jan;57(1):425-35. doi: 10.1128/AAC.00920-12. Epub 2012 Nov 5.

2.

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.

Delves M, Plouffe D, Scheurer C, Meister S, Wittlin S, Winzeler EA, Sinden RE, Leroy D.

PLoS Med. 2012 Feb;9(2):e1001169. doi: 10.1371/journal.pmed.1001169. Epub 2012 Feb 21.

3.

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.

Biagini GA, Fisher N, Shone AE, Mubaraki MA, Srivastava A, Hill A, Antoine T, Warman AJ, Davies J, Pidathala C, Amewu RK, Leung SC, Sharma R, Gibbons P, Hong DW, Pacorel B, Lawrenson AS, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Stocks PA, Nixon GL, Chadwick J, Hemingway J, Delves MJ, Sinden RE, Zeeman AM, Kocken CH, Berry NG, O'Neill PM, Ward SA.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8298-303. doi: 10.1073/pnas.1205651109. Epub 2012 May 7.

4.

Effects of the antimalarial drugs ferroquine and artesunate on Plasmodium yoelii yoelii gametocytegenesis and vectorial transmission.

Mustfa K, Landau I, Chabaud AG, Chavatte JM, Chandenier J, Duong TH, Richard-Lenoble D.

Sante. 2011 Jul-Sep;21(3):133-42. doi: 10.1684/san.2011.0261.

5.

Mosquito ingestion of antibodies against mosquito midgut microbiota improves conversion of ookinetes to oocysts for Plasmodium falciparum, but not P. yoelii.

Noden BH, Vaughan JA, Pumpuni CB, Beier JC.

Parasitol Int. 2011 Dec;60(4):440-6. doi: 10.1016/j.parint.2011.07.007. Epub 2011 Jul 13.

6.

Strategic use of antimalarial drugs that block falciparum malaria parasite transmission to mosquitoes to achieve local malaria elimination.

Abdul-Ghani R, Beier JC.

Parasitol Res. 2014 Oct;113(10):3535-46. doi: 10.1007/s00436-014-4091-6. Epub 2014 Sep 4. Review.

PMID:
25185662
7.

Nasal immunization with a malaria transmission-blocking vaccine candidate, Pfs25, induces complete protective immunity in mice against field isolates of Plasmodium falciparum.

Arakawa T, Komesu A, Otsuki H, Sattabongkot J, Udomsangpetch R, Matsumoto Y, Tsuji N, Wu Y, Torii M, Tsuboi T.

Infect Immun. 2005 Nov;73(11):7375-80.

8.

Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites.

Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH.

ACS Chem Biol. 2015 Mar 20;10(3):775-83. doi: 10.1021/cb500981y. Epub 2015 Jan 30.

9.

4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni.

Sáenz FE, Lacrue AN, Cross RM, Maignan JR, Udenze KO, Manetsch R, Kyle DE.

Antimicrob Agents Chemother. 2013 Dec;57(12):6187-95. doi: 10.1128/AAC.00492-13. Epub 2013 Sep 30.

10.

Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.

Hallett RL, Sutherland CJ, Alexander N, Ord R, Jawara M, Drakeley CJ, Pinder M, Walraven G, Targett GA, Alloueche A.

Antimicrob Agents Chemother. 2004 Oct;48(10):3940-3.

11.

A polymorphic drug pump in the malaria parasite.

Saliba KJ, Lehane AM, Kirk K.

Mol Microbiol. 2008 Nov;70(4):775-9. doi: 10.1111/j.1365-2958.2008.06451.x.

12.

Gene targeting in the rodent malaria parasite Plasmodium yoelii.

Mota MM, Thathy V, Nussenzweig RS, Nussenzweig V.

Mol Biochem Parasitol. 2001 Apr 6;113(2):271-8.

PMID:
11295181
13.
14.

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy.

Milner E, Sousa J, Pybus B, Auschwitz J, Caridha D, Gardner S, Grauer K, Harris E, Hickman M, Kozar MP, Lee P, Leed S, Li Q, Melendez V, Moon J, Ngundam F, O'Neil M, Parriott S, Potter B, Sciotti R, Tangteung A, Dow GS.

Eur J Drug Metab Pharmacokinet. 2012 Mar;37(1):17-22.

PMID:
22314893
15.

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.

Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, Groessl T, Kato N, Lee MC, McNamara CW, Fidock DA, Nagle A, Nam TG, Richmond W, Roland J, Rottmann M, Zhou B, Froissard P, Glynne RJ, Mazier D, Sattabongkot J, Schultz PG, Tuntland T, Walker JR, Zhou Y, Chatterjee A, Diagana TT, Winzeler EA.

Science. 2011 Dec 9;334(6061):1372-7. doi: 10.1126/science.1211936. Epub 2011 Nov 17.

16.

A class of potent antimalarials and their specific accumulation in infected erythrocytes.

Wengelnik K, Vidal V, Ancelin ML, Cathiard AM, Morgat JL, Kocken CH, Calas M, Herrera S, Thomas AW, Vial HJ.

Science. 2002 Feb 15;295(5558):1311-4.

17.

A plant-derived morphinan as a novel lead compound active against malaria liver stages.

Carraz M, Jossang A, Franetich JF, Siau A, Ciceron L, Hannoun L, Sauerwein R, Frappier F, Rasoanaivo P, Snounou G, Mazier D.

PLoS Med. 2006 Dec;3(12):e513.

18.

Malaria ookinete surface protein-based vaccination via the intranasal route completely blocks parasite transmission in both passive and active vaccination regimens in a rodent model of malaria infection.

Arakawa T, Tachibana M, Miyata T, Harakuni T, Kohama H, Matsumoto Y, Tsuji N, Hisaeda H, Stowers A, Torii M, Tsuboi T.

Infect Immun. 2009 Dec;77(12):5496-500. doi: 10.1128/IAI.00640-09. Epub 2009 Sep 14.

19.

Functional genomics, new tools in malaria research.

Di Girolamo F, Raggi C, Bultrini E, Lanfrancotti A, Silvestrini F, Sargiacomo M, Birago C, Pizzi E, Alano P, Ponzi M.

Ann Ist Super Sanita. 2005;41(4):469-77. Review.

20.

That was then but this is now: malaria research in the time of an eradication agenda.

Kappe SH, Vaughan AM, Boddey JA, Cowman AF.

Science. 2010 May 14;328(5980):862-6. doi: 10.1126/science.1184785. Review.

PMID:
20466924

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