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Items: 1 to 20 of 133

1.

Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells.

Yan Y, Gong K, Ma T, Zhang L, Zhao N, Zhang X, Tang P, Gong Y.

Neurosci Lett. 2012 Dec 7;531(2):160-5. doi: 10.1016/j.neulet.2012.10.043. Epub 2012 Nov 2.

PMID:
23127846
2.

Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats.

Zhou S, Yu G, Chi L, Zhu J, Zhang W, Zhang Y, Zhang L.

Neurotoxicology. 2013 Sep;38:136-45. doi: 10.1016/j.neuro.2013.07.007. Epub 2013 Aug 7.

3.

Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.

Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.

J Pharmacol Exp Ther. 2009 May;329(2):687-98. doi: 10.1124/jpet.108.148676. Epub 2009 Feb 6.

4.

Edaravone ameliorates oxidative damage associated with Aβ25-35 treatment in PC12 cells.

Zhang GL, Zhang WG, Du Y, Yao L, Sun H, Zhang R, Liu E, Bu N, Wu HQ, Zhang L, Li TT, Guo YY.

J Mol Neurosci. 2013 Jul;50(3):494-503. doi: 10.1007/s12031-013-9973-z. Epub 2013 Feb 8.

PMID:
23393032
5.

[Research and development of the free radical scavenger edaravone as a neuroprotectant].

Watanabe T, Tanaka M, Watanabe K, Takamatsu Y, Tobe A.

Yakugaku Zasshi. 2004 Mar;124(3):99-111. Review. Japanese.

6.

Effects of edaravone in heart of aged rats after cerebral ischemia-reperfusion injury.

Watanabe K, Ma M, Wen J, Kodama M, Aizawa Y.

Biol Pharm Bull. 2007 Mar;30(3):460-4.

7.

Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats.

Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.

J Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27.

8.

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.

Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I.

J Pharmacol Exp Ther. 2009 Jun;329(3):865-74. doi: 10.1124/jpet.108.149484. Epub 2009 Mar 17.

9.

Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease.

Li B, Yu D, Xu Z.

J Mol Neurosci. 2013 Oct;51(2):539-49. doi: 10.1007/s12031-013-0022-8. Epub 2013 May 10.

PMID:
23657982
10.

Edaravone protects cortical neurons from apoptosis by inhibiting the translocation of BAX and Increasing the interaction between 14-3-3 and p-BAD.

Fan J, Zhang N, Yin G, Zhang Z, Cheng G, Qian W, Long H, Cai W.

Int J Neurosci. 2012 Nov;122(11):665-74. doi: 10.3109/00207454.2012.707714. Epub 2012 Aug 21.

PMID:
22757651
11.

Protective effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced acute kidney injury in a rat model of sepsis.

Liu L, Song Y, Zhao M, Yi Z, Zeng Q.

Int Urol Nephrol. 2015 Oct;47(10):1745-52. doi: 10.1007/s11255-015-1070-5. Epub 2015 Aug 25.

PMID:
26300162
12.

Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment.

Roh MI, Murakami Y, Thanos A, Vavvas DG, Miller JW.

Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3825-31. doi: 10.1167/iovs.10-6797.

13.

Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.

Jami MS, Salehi-Najafabadi Z, Ahmadinejad F, Hoedt E, Chaleshtori MH, Ghatrehsamani M, Neubert TA, Larsen JP, Møller SG.

Neurochem Int. 2015 Nov;90:134-41. doi: 10.1016/j.neuint.2015.07.024. Epub 2015 Jul 29.

14.

Edaravone protects against ischemia/reperfusion-induced oxidative damage to mitochondria in rat liver.

Okatani Y, Wakatsuki A, Enzan H, Miyahara Y.

Eur J Pharmacol. 2003 Mar 28;465(1-2):163-70.

PMID:
12650846
15.

Edaravone protects against MPP+ -induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway.

Chen H, Wang S, Ding JH, Hu G.

J Neurochem. 2008 Sep;106(6):2345-52. doi: 10.1111/j.1471-4159.2008.05573.x. Epub 2008 Jul 15.

16.

Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax.

Miyasou T, Kwon AH, Tsuji K, Qiu Z, Okumura T, Kamiyama Y.

Shock. 2008 Aug;30(2):212-6. doi: 10.1097/shk.0b013e31816171f4.

PMID:
18180697
17.

Antioxidants and neuroprotection in the adult and developing central nervous system.

Kaur C, Ling EA.

Curr Med Chem. 2008;15(29):3068-80. Review.

PMID:
19075654
18.

Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture.

Hisano K, Watanabe M, Morimoto Y.

J Anesth. 2009;23(3):363-9. doi: 10.1007/s00540-009-0766-z. Epub 2009 Aug 14.

PMID:
19685116
19.

Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway.

Zhao ZY, Luan P, Huang SX, Xiao SH, Zhao J, Zhang B, Gu BB, Pi RB, Liu J.

CNS Neurosci Ther. 2013 Mar;19(3):163-9. doi: 10.1111/cns.12044. Epub 2012 Dec 18.

PMID:
23253171
20.

Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease.

Sheng B, Gong K, Niu Y, Liu L, Yan Y, Lu G, Zhang L, Hu M, Zhao N, Zhang X, Tang P, Gong Y.

Free Radic Biol Med. 2009 May 15;46(10):1362-75. doi: 10.1016/j.freeradbiomed.2009.02.018. Epub 2009 Mar 3.

PMID:
19264123

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