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Items: 1 to 20 of 185

1.

IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells.

Hasnain SZ, Tauro S, Das I, Tong H, Chen AC, Jeffery PL, McDonald V, Florin TH, McGuckin MA.

Gastroenterology. 2013 Feb;144(2):357-368.e9. doi: 10.1053/j.gastro.2012.10.043. Epub 2012 Oct 31.

PMID:
23123183
2.

Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.

Das I, Png CW, Oancea I, Hasnain SZ, Lourie R, Proctor M, Eri RD, Sheng Y, Crane DI, Florin TH, McGuckin MA.

J Exp Med. 2013 Jun 3;210(6):1201-16. doi: 10.1084/jem.20121268. Epub 2013 May 6.

3.

Intestinal secretory cell ER stress and inflammation.

McGuckin MA, Eri RD, Das I, Lourie R, Florin TH.

Biochem Soc Trans. 2011 Aug;39(4):1081-5. doi: 10.1042/BST0391081.

PMID:
21787352
4.

An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity.

Eri RD, Adams RJ, Tran TV, Tong H, Das I, Roche DK, Oancea I, Png CW, Jeffery PL, Radford-Smith GL, Cook MC, Florin TH, McGuckin MA.

Mucosal Immunol. 2011 May;4(3):354-64. doi: 10.1038/mi.2010.74. Epub 2010 Nov 24.

5.

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation.

Shkoda A, Ruiz PA, Daniel H, Kim SC, Rogler G, Sartor RB, Haller D.

Gastroenterology. 2007 Jan;132(1):190-207. Epub 2006 Oct 21.

PMID:
17241871
6.

ER stress and the unfolded protein response in intestinal inflammation.

McGuckin MA, Eri RD, Das I, Lourie R, Florin TH.

Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G820-32. doi: 10.1152/ajpgi.00063.2010. Epub 2010 Mar 25. Review.

7.

Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation.

Messlik A, Schmechel S, Kisling S, Bereswill S, Heimesaat MM, Fischer A, Göbel U, Haller D.

J Proteome Res. 2009 Oct;8(10):4406-17. doi: 10.1021/pr9000465.

PMID:
19681597
8.

Kaempferol Inhibits Endoplasmic Reticulum Stress-Associated Mucus Hypersecretion in Airway Epithelial Cells And Ovalbumin-Sensitized Mice.

Park SH, Gong JH, Choi YJ, Kang MK, Kim YH, Kang YH.

PLoS One. 2015 Nov 24;10(11):e0143526. doi: 10.1371/journal.pone.0143526. eCollection 2015.

9.

γδ T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer.

Kober OI, Ahl D, Pin C, Holm L, Carding SR, Juge N.

Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G582-93. doi: 10.1152/ajpgi.00218.2013. Epub 2014 Feb 6.

10.

Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice.

Shinoda M, Shin-Ya M, Naito Y, Kishida T, Ito R, Suzuki N, Yasuda H, Sakagami J, Imanishi J, Kataoka K, Mazda O, Yoshikawa T.

J Gastroenterol. 2010 Jun;45(6):608-17. doi: 10.1007/s00535-010-0210-z. Epub 2010 Feb 19.

PMID:
20169455
11.

Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer.

Saxena A, Baliga MS, Ponemone V, Kaur K, Larsen B, Fletcher E, Greene J, Fayad R.

Int J Colorectal Dis. 2013 Sep;28(9):1267-79. doi: 10.1007/s00384-013-1664-2. Epub 2013 Mar 9.

12.

Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice.

Tréton X, Pedruzzi E, Guichard C, Ladeiro Y, Sedghi S, Vallée M, Fernandez N, Bruyère E, Woerther PL, Ducroc R, Montcuquet N, Freund JN, Van Seuningen I, Barreau F, Marah A, Hugot JP, Cazals-Hatem D, Bouhnik Y, Daniel F, Ogier-Denis E.

PLoS One. 2014 Jul 9;9(7):e101669. doi: 10.1371/journal.pone.0101669. eCollection 2014.

13.

Erlotinib promotes endoplasmic reticulum stress-mediated injury in the intestinal epithelium.

Fan L, Hu L, Yang B, Fang X, Gao Z, Li W, Sun Y, Shen Y, Wu X, Shu Y, Gu Y, Wu X, Xu Q.

Toxicol Appl Pharmacol. 2014 Jul 1;278(1):45-52. doi: 10.1016/j.taap.2014.04.015. Epub 2014 Apr 24.

PMID:
24768708
14.

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent.

Wrzosek L, Miquel S, Noordine ML, Bouet S, Joncquel Chevalier-Curt M, Robert V, Philippe C, Bridonneau C, Cherbuy C, Robbe-Masselot C, Langella P, Thomas M.

BMC Biol. 2013 May 21;11:61. doi: 10.1186/1741-7007-11-61.

15.

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.

Gulhane M, Murray L, Lourie R, Tong H, Sheng YH, Wang R, Kang A, Schreiber V, Wong KY, Magor G, Denman S, Begun J, Florin TH, Perkins A, Cuív PÓ, McGuckin MA, Hasnain SZ.

Sci Rep. 2016 Jun 28;6:28990. doi: 10.1038/srep28990.

16.

Resistin-like molecule beta regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice.

Krimi RB, Kotelevets L, Dubuquoy L, Plaisancié P, Walker F, Lehy T, Desreumaux P, Van Seuningen I, Chastre E, Forgue-Lafitte ME, Marie JC.

Inflamm Bowel Dis. 2008 Jul;14(7):931-41. doi: 10.1002/ibd.20420.

PMID:
18300276
17.

Interleukin-9 upregulates mucus expression in the airways.

Louahed J, Toda M, Jen J, Hamid Q, Renauld JC, Levitt RC, Nicolaides NC.

Am J Respir Cell Mol Biol. 2000 Jun;22(6):649-56.

PMID:
10837360
18.

Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4.

Burger-van Paassen N, Loonen LM, Witte-Bouma J, Korteland-van Male AM, de Bruijn AC, van der Sluis M, Lu P, Van Goudoever JB, Wells JM, Dekker J, Van Seuningen I, Renes IB.

PLoS One. 2012;7(6):e38798. doi: 10.1371/journal.pone.0038798. Epub 2012 Jun 19.

19.

The endoplasmic reticulum stress transducer OASIS is involved in the terminal differentiation of goblet cells in the large intestine.

Asada R, Saito A, Kawasaki N, Kanemoto S, Iwamoto H, Oki M, Miyagi H, Izumi S, Imaizumi K.

J Biol Chem. 2012 Mar 9;287(11):8144-53. doi: 10.1074/jbc.M111.332593. Epub 2012 Jan 19.

20.

Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice.

van der Sluis M, Bouma J, Vincent A, Velcich A, Carraway KL, Büller HA, Einerhand AW, van Goudoever JB, Van Seuningen I, Renes IB.

Lab Invest. 2008 Jun;88(6):634-42. doi: 10.1038/labinvest.2008.28. Epub 2008 Apr 21.

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