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Items: 1 to 20 of 89

1.

Distinct and overlapping genomic profiles and antiviral effects of Interferon-λ and -α on HCV-infected and noninfected hepatoma cells.

Kohli A, Zhang X, Yang J, Russell RS, Donnelly RP, Sheikh F, Sherman A, Young H, Imamichi T, Lempicki RA, Masur H, Kottilil S.

J Viral Hepat. 2012 Dec;19(12):843-53. doi: 10.1111/j.1365-2893.2012.01610.x. Epub 2012 May 27.

2.

Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.

Ferraris P, Chandra PK, Panigrahi R, Aboulnasr F, Chava S, Kurt R, Pawlotsky JM, Wilkens L, Osterlund P, Hartmann R, Balart LA, Wu T, Dash S.

Am J Pathol. 2016 Apr;186(4):938-51. doi: 10.1016/j.ajpath.2015.11.027. Epub 2016 Feb 16.

PMID:
26896692
3.

IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S.

PLoS One. 2015 Dec 11;10(12):e0141655. doi: 10.1371/journal.pone.0141655. eCollection 2015.

4.

Pegylated interferons Lambda-1a and alfa-2a display different gene induction and cytokine and chemokine release profiles in whole blood, human hepatocytes and peripheral blood mononuclear cells.

Freeman J, Baglino S, Friborg J, Kraft Z, Gray T, Hill M, McPhee F, Hillson J, Lopez-Talavera JC, Wind-Rotolo M.

J Viral Hepat. 2014 Jun;21(6):e1-9. doi: 10.1111/jvh.12243.

PMID:
24827902
5.

Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics.

Marcello T, Grakoui A, Barba-Spaeth G, Machlin ES, Kotenko SV, MacDonald MR, Rice CM.

Gastroenterology. 2006 Dec;131(6):1887-98. Epub 2006 Oct 1.

PMID:
17087946
6.

Persistence of HCV in quiescent hepatic cells under conditions of an interferon-induced antiviral response.

Bauhofer O, Ruggieri A, Schmid B, Schirmacher P, Bartenschlager R.

Gastroenterology. 2012 Aug;143(2):429-38.e8. doi: 10.1053/j.gastro.2012.04.018. Epub 2012 Apr 19.

PMID:
22522091
7.

IL-28B (IFN-λ3) and IFN-α synergistically inhibit HCV replication.

Shindo H, Maekawa S, Komase K, Miura M, Kadokura M, Sueki R, Komatsu N, Shindo K, Amemiya F, Nakayama Y, Inoue T, Sakamoto M, Yamashita A, Moriishi K, Enomoto N.

J Viral Hepat. 2013 Apr;20(4):281-9. doi: 10.1111/j.1365-2893.2012.01649.x. Epub 2012 Aug 7.

PMID:
23490373
8.

Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus.

Jilg N, Lin W, Hong J, Schaefer EA, Wolski D, Meixong J, Goto K, Brisac C, Chusri P, Fusco DN, Chevaliez S, Luther J, Kumthip K, Urban TJ, Peng LF, Lauer GM, Chung RT.

Hepatology. 2014 Apr;59(4):1250-61. doi: 10.1002/hep.26653. Epub 2014 Feb 14.

9.

Impairment of type I but not type III IFN signaling by hepatitis C virus infection influences antiviral responses in primary human hepatocytes.

Friborg J, Ross-Macdonald P, Cao J, Willard R, Lin B, Eggers B, McPhee F.

PLoS One. 2015 Mar 31;10(3):e0121734. doi: 10.1371/journal.pone.0121734. eCollection 2015.

10.

Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes.

Dickensheets H, Sheikh F, Park O, Gao B, Donnelly RP.

J Leukoc Biol. 2013 Mar;93(3):377-85. doi: 10.1189/jlb.0812395. Epub 2012 Dec 20.

11.

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway.

Hazari S, Chandra PK, Poat B, Datta S, Garry RF, Foster TP, Kousoulas G, Wakita T, Dash S.

Virol J. 2010 Feb 11;7:36. doi: 10.1186/1743-422X-7-36.

12.

A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus.

Zhao H, Lin W, Kumthip K, Cheng D, Fusco DN, Hofmann O, Jilg N, Tai AW, Goto K, Zhang L, Hide W, Jang JY, Peng LF, Chung RT.

J Hepatol. 2012 Feb;56(2):326-33. doi: 10.1016/j.jhep.2011.07.026. Epub 2011 Aug 31.

13.

Human type 2 myeloid dendritic cells produce interferon-λ and amplify interferon-α in response to hepatitis C virus infection.

Zhang S, Kodys K, Li K, Szabo G.

Gastroenterology. 2013 Feb;144(2):414-425.e7. doi: 10.1053/j.gastro.2012.10.034. Epub 2012 Oct 23.

14.

Induction of interferon-λ contributes to Toll-like receptor-3-activated hepatic stellate cell-mediated hepatitis C virus inhibition in hepatocytes.

Wang Y, Li J, Wang X, Ye L, Zhou Y, Ho W.

J Viral Hepat. 2013 Jun;20(6):385-94. doi: 10.1111/jvh.12040. Epub 2013 Jan 7.

15.

Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line.

Zhu H, Zhao H, Collins CD, Eckenrode SE, Run Q, McIndoe RA, Crawford JM, Nelson DR, She JX, Liu C.

Hepatology. 2003 May;37(5):1180-8.

PMID:
12717400
16.

Ribavirin regulates hepatitis C virus replication through enhancing interferon-stimulated genes and interleukin 8.

Tokumoto Y, Hiasa Y, Uesugi K, Watanabe T, Mashiba T, Abe M, Kumagi T, Ikeda Y, Matsuura B, Onji M.

J Infect Dis. 2012 Apr 1;205(7):1121-30. doi: 10.1093/infdis/jis025. Epub 2012 Feb 21.

PMID:
22357660
17.

Transcriptional regulation of IFN-λ genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex.

Lee HC, Narayanan S, Park SJ, Seong SY, Hahn YS.

J Biol Chem. 2014 Feb 21;289(8):5310-9. doi: 10.1074/jbc.M113.536102. Epub 2014 Jan 2. Erratum in: J Biol Chem. 2014 Apr 25;289(17):11861.

18.

High-throughput profiling of alpha interferon- and interleukin-28B-regulated microRNAs and identification of let-7s with anti-hepatitis C virus activity by targeting IGF2BP1.

Cheng M, Si Y, Niu Y, Liu X, Li X, Zhao J, Jin Q, Yang W.

J Virol. 2013 Sep;87(17):9707-18. doi: 10.1128/JVI.00802-13. Epub 2013 Jul 3.

19.

Novel type I interferon IL-28A suppresses hepatitis C viral RNA replication.

Zhu H, Butera M, Nelson DR, Liu C.

Virol J. 2005 Sep 7;2:80.

20.

Isolation and characterization of interferon lambda-resistant hepatitis C virus replicon cell lines.

Friborg J, Lin B, Chen C, McPhee F.

Virology. 2013 Sep;444(1-2):384-93. doi: 10.1016/j.virol.2013.07.005. Epub 2013 Jul 25.

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