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Items: 1 to 20 of 95


Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza.

Zheng D, Limmon GV, Yin L, Leung NH, Yu H, Chow VT, Chen J.

PLoS One. 2012;7(10):e48451. doi: 10.1371/journal.pone.0048451. Epub 2012 Oct 31.


A cellular pathway involved in Clara cell to alveolar type II cell differentiation after severe lung injury.

Zheng D, Limmon GV, Yin L, Leung NH, Yu H, Chow VT, Chen J.

PLoS One. 2013 Aug 5;8(8):e71028. doi: 10.1371/journal.pone.0071028. Print 2013.


Evidence for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.

Zheng D, Yin L, Chen J.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):595-604. doi: 10.1165/rcmb.2013-0327OC.


Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia.

Yin L, Zheng D, Limmon GV, Leung NH, Xu S, Rajapakse JC, Yu H, Chow VT, Chen J.

Respir Res. 2014 Sep 30;15:116. doi: 10.1186/s12931-014-0116-z.


Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells.

Yee M, Buczynski BW, O'Reilly MA.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):757-66. doi: 10.1165/rcmb.2013-0207OC.


The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.

Rawlins EL, Okubo T, Xue Y, Brass DM, Auten RL, Hasegawa H, Wang F, Hogan BL.

Cell Stem Cell. 2009 Jun 5;4(6):525-34. doi: 10.1016/j.stem.2009.04.002.


Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo.

Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H.

Exp Lung Res. 2015;41(8):422-34. doi: 10.3109/01902148.2015.1060275. Epub 2015 Jul 7.


Differentiation of mouse induced pluripotent stem cells into alveolar epithelial cells in vitro for use in vivo.

Zhou Q, Ye X, Sun R, Matsumoto Y, Moriyama M, Asano Y, Ajioka Y, Saijo Y.

Stem Cells Transl Med. 2014 Jun;3(6):675-85. doi: 10.5966/sctm.2013-0142. Epub 2014 Apr 24.


Surfactant protein-C chromatin-bound green fluorescence protein reporter mice reveal heterogeneity of surfactant protein C-expressing lung cells.

Lee JH, Kim J, Gludish D, Roach RR, Saunders AH, Barrios J, Woo AJ, Chen H, Conner DA, Fujiwara Y, Stripp BR, Kim CF.

Am J Respir Cell Mol Biol. 2013 Mar;48(3):288-98. doi: 10.1165/rcmb.2011-0403OC. Epub 2012 Nov 29.


Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury.

Bhandary YP, Shetty SK, Marudamuthu AS, Midde KK, Ji HL, Shams H, Subramaniam R, Fu J, Idell S, Shetty S.

PLoS One. 2015 May 1;10(5):e0123187. doi: 10.1371/journal.pone.0123187. eCollection 2015.


Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein.

Manning CM, Johnston CJ, Hernady E, Miller JN, Reed CK, Lawrence BP, Williams JP, Finkelstein JN.

Radiat Res. 2013 Jun;179(6):617-29. doi: 10.1667/RR3279.1. Epub 2013 Apr 26.


TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.

Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE.

Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L887-97. doi: 10.1152/ajplung.00397.2010. Epub 2011 Mar 25.


Spatiotemporal quantification of cell dynamics in the lung following influenza virus infection.

Yin L, Xu S, Cheng J, Zheng D, Limmon GV, Leung NH, Rajapakse JC, Chow VT, Chen J, Yu H.

J Biomed Opt. 2013 Apr;18(4):046001. doi: 10.1117/1.JBO.18.4.046001.


Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair.

Garcia O, Hiatt MJ, Lundin A, Lee J, Reddy R, Navarro S, Kikuchi A, Driscoll B.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):319-30. doi: 10.1165/rcmb.2014-0246OC.


Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis.

Ohta H, Chiba S, Ebina M, Furuse M, Nukiwa T.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15;302(2):L193-205. doi: 10.1152/ajplung.00349.2010. Epub 2011 Oct 14.


Effect of recombinant IL-10 on cultured fetal rat alveolar type II cells exposed to 65%-hyperoxia.

Lee HS, Kim CK.

Respir Res. 2011 May 24;12:68. doi: 10.1186/1465-9921-12-68.


Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice.

Chapman HA, Li X, Alexander JP, Brumwell A, Lorizio W, Tan K, Sonnenberg A, Wei Y, Vu TH.

J Clin Invest. 2011 Jul;121(7):2855-62. doi: 10.1172/JCI57673. Epub 2011 Jun 23. Erratum in: J Clin Invest. 2011 Aug 1;121(8):3360.


Regulation of type II alveolar epithelial cell proliferation by TGF-beta during bleomycin-induced lung injury in rats.

Khalil N, O'Connor RN, Flanders KC, Shing W, Whitman CI.

Am J Physiol. 1994 Nov;267(5 Pt 1):L498-507.


Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1.

Bhandary YP, Shetty SK, Marudamuthu AS, Ji HL, Neuenschwander PF, Boggaram V, Morris GF, Fu J, Idell S, Shetty S.

Am J Pathol. 2013 Jul;183(1):131-43. doi: 10.1016/j.ajpath.2013.03.022. Epub 2013 May 8.


A change in the number of CCSP(pos)/SPC(pos) cells in mouse lung during development, growth, and repair.

Sun R, Zhou Q, Ye X, Takahata T, Ishiguro A, Kijima H, Nukiwa T, Saijo Y.

Respir Investig. 2013 Dec;51(4):229-40. doi: 10.1016/j.resinv.2013.04.006. Epub 2013 Jun 4.


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