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Items: 1 to 20 of 137

1.

Compromised genomic integrity impedes muscle growth after Atrx inactivation.

Huh MS, Price O'Dea T, Ouazia D, McKay BC, Parise G, Parks RJ, Rudnicki MA, Picketts DJ.

J Clin Invest. 2012 Dec;122(12):4412-23. doi: 10.1172/JCI63765. Epub 2012 Nov 1.

2.

Stalled replication forks within heterochromatin require ATRX for protection.

Huh MS, Ivanochko D, Hashem LE, Curtin M, Delorme M, Goodall E, Yan K, Picketts DJ.

Cell Death Dis. 2016 May 12;7:e2220. doi: 10.1038/cddis.2016.121.

3.

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome.

Bagheri-Fam S, Argentaro A, Svingen T, Combes AN, Sinclair AH, Koopman P, Harley VR.

Hum Mol Genet. 2011 Jun 1;20(11):2213-24. doi: 10.1093/hmg/ddr109. Epub 2011 Mar 22. Erratum in: Hum Mol Genet. 2011 Sep 1;20(17):3535.

PMID:
21427128
4.

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells.

Wong LH, McGhie JD, Sim M, Anderson MA, Ahn S, Hannan RD, George AJ, Morgan KA, Mann JR, Choo KH.

Genome Res. 2010 Mar;20(3):351-60. doi: 10.1101/gr.101477.109. Epub 2010 Jan 28.

5.

ATRX has a critical and conserved role in mammalian sexual differentiation.

Huyhn K, Renfree MB, Graves JA, Pask AJ.

BMC Dev Biol. 2011 Jun 14;11:39. doi: 10.1186/1471-213X-11-39.

6.

Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.

Leung JW, Ghosal G, Wang W, Shen X, Wang J, Li L, Chen J.

J Biol Chem. 2013 Mar 1;288(9):6342-50. doi: 10.1074/jbc.M112.411603. Epub 2013 Jan 16.

7.

The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis.

Bérubé NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, Picketts DJ.

J Clin Invest. 2005 Feb;115(2):258-67.

8.

ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions.

Levy MA, Kernohan KD, Jiang Y, Bérubé NG.

Hum Mol Genet. 2015 Apr 1;24(7):1824-35. doi: 10.1093/hmg/ddu596. Epub 2014 Dec 1.

PMID:
25452430
9.

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage.

Vadnais C, Davoudi S, Afshin M, Harada R, Dudley R, Clermont PL, Drobetsky E, Nepveu A.

Nucleic Acids Res. 2012 May;40(10):4483-95. doi: 10.1093/nar/gks041. Epub 2012 Feb 8.

10.

Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.

Medina CF, Mazerolle C, Wang Y, Bérubé NG, Coupland S, Gibbons RJ, Wallace VA, Picketts DJ.

Hum Mol Genet. 2009 Mar 1;18(5):966-77. doi: 10.1093/hmg/ddn424. Epub 2008 Dec 16.

PMID:
19088125
11.

Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease.

De La Fuente R, Baumann C, Viveiros MM.

Reproduction. 2011 Aug;142(2):221-34. doi: 10.1530/REP-10-0380. Epub 2011 Jun 8. Review.

12.

ATRX in chromatin assembly and genome architecture during development and disease.

Bérubé NG.

Biochem Cell Biol. 2011 Oct;89(5):435-44. doi: 10.1139/o11-038. Epub 2011 Aug 18.

PMID:
21851155
13.

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9.

Dhayalan A, Tamas R, Bock I, Tattermusch A, Dimitrova E, Kudithipudi S, Ragozin S, Jeltsch A.

Hum Mol Genet. 2011 Jun 1;20(11):2195-203. doi: 10.1093/hmg/ddr107. Epub 2011 Mar 18.

14.

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.

Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Bérubé NG.

J Neurosci. 2008 Nov 19;28(47):12570-80. doi: 10.1523/JNEUROSCI.4048-08.2008.

15.

ATRX and the replication of structured DNA.

Clynes D, Gibbons RJ.

Curr Opin Genet Dev. 2013 Jun;23(3):289-94. doi: 10.1016/j.gde.2013.01.005. Epub 2013 Feb 28. Review.

PMID:
23453691
16.

[X-linked alpha-thalassemia/mental retardation syndrome].

Wada T.

Rinsho Byori. 2009 Apr;57(4):382-90. Review. Japanese.

PMID:
19489441
17.

ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain.

Kernohan KD, Jiang Y, Tremblay DC, Bonvissuto AC, Eubanks JH, Mann MR, Bérubé NG.

Dev Cell. 2010 Feb 16;18(2):191-202. doi: 10.1016/j.devcel.2009.12.017.

18.

Retinal interneuron survival requires non-cell-autonomous Atrx activity.

Lagali PS, Medina CF, Zhao BY, Yan K, Baker AN, Coupland SG, Tsilfidis C, Wallace VA, Picketts DJ.

Hum Mol Genet. 2016 Nov 1;25(21):4787-4803. doi: 10.1093/hmg/ddw306.

PMID:
28173139
19.

Patient mutations alter ATRX targeting to PML nuclear bodies.

Bérubé NG, Healy J, Medina CF, Wu S, Hodgson T, Jagla M, Picketts DJ.

Eur J Hum Genet. 2008 Feb;16(2):192-201. Epub 2007 Oct 24.

20.

Alpha-thalassemia X-linked intellectual disability syndrome identified by whole exome sequencing in two boys with white matter changes and developmental retardation.

Lee JS, Lee S, Lim BC, Kim KJ, Hwang YS, Choi M, Chae JH.

Gene. 2015 Sep 15;569(2):318-22. doi: 10.1016/j.gene.2015.04.075. Epub 2015 Apr 30.

PMID:
25936994

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