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Epidermal growth factor-induced modulation of cytokeratin expression levels influences the morphological phenotype of head and neck squamous cell carcinoma cells.

Makarova G, Bette M, Schmidt A, Jacob R, Cai C, Rodepeter F, Betz T, Sitterberg J, Bakowsky U, Moll R, Neff A, Sesterhenn A, Teymoortash A, Ocker M, Werner JA, Mandic R.

Cell Tissue Res. 2013 Jan;351(1):59-72. doi: 10.1007/s00441-012-1500-y. Epub 2012 Nov 1.


Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.

O-charoenrat P, Modjtahedi H, Rhys-Evans P, Court WJ, Box GM, Eccles SA.

Cancer Res. 2000 Feb 15;60(4):1121-8.


Cisplatin resistance of the HNSCC cell line UT-SCC-26A can be overcome by stimulation of the EGF-receptor.

Mandic R, Rodgarkia-Dara CJ, Krohn V, Wiegand S, Grénman R, Werner JA.

Anticancer Res. 2009 Apr;29(4):1181-7.


EGF-dependent induction of BCL-xL and p21CIP1/WAF1 is highly variable in HNSCC cells--implications for EGFR-targeted therapies.

Rüddel J, Wennekes VE, Meissner W, Werner JA, Mandic R.

Anticancer Res. 2010 Nov;30(11):4579-85.


Regulation of heparin-binding EGF-like growth factor by miR-212 and acquired cetuximab-resistance in head and neck squamous cell carcinoma.

Hatakeyama H, Cheng H, Wirth P, Counsell A, Marcrom SR, Wood CB, Pohlmann PR, Gilbert J, Murphy B, Yarbrough WG, Wheeler DL, Harari PM, Guo Y, Shyr Y, Slebos RJ, Chung CH.

PLoS One. 2010 Sep 13;5(9):e12702. doi: 10.1371/journal.pone.0012702.


Restoration of BRAK / CXCL14 gene expression by gefitinib is associated with antitumor efficacy of the drug in head and neck squamous cell carcinoma.

Ozawa S, Kato Y, Ito S, Komori R, Shiiki N, Tsukinoki K, Ozono S, Maehata Y, Taguchi T, Imagawa-Ishiguro Y, Tsukuda M, Kubota E, Hata R.

Cancer Sci. 2009 Nov;100(11):2202-9. doi: 10.1111/j.1349-7006.2009.01281.x. Epub 2009 Aug 8.


Suppression by retinoic acid of epidermal growth factor receptor autophosphorylation and glycosylation in cultured human head and neck squamous carcinoma cells.

Kim JS, Steck PA, Gallick GE, Lee JS, Blick M, Hong WK, Lotan R.

J Natl Cancer Inst Monogr. 1992;(13):101-10.


Variations of EGF-R surface expression in squamous cell carcinomas of the head and neck region.

Mandic R, Eikelkamp N, Peldszus R, Sadowski M, Sesterhenn AM, Dünne AA, Werner JA.

Anticancer Res. 2001 Sep-Oct;21(5):3413-8.


Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.

Cohen EE, Lingen MW, Zhu B, Zhu H, Straza MW, Pierce C, Martin LE, Rosner MR.

Cancer Res. 2006 Jun 15;66(12):6296-303.


Cytokeratins 6 and 16 are frequently expressed in head and neck squamous cell carcinoma cell lines and fresh biopsies.

Sesterhenn AM, Mandic R, Dünne AA, Werner JA.

Anticancer Res. 2005 Jul-Aug;25(4):2675-80.


Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.

Fantozzi I, Grall D, Cagnol S, Stanchi F, Sudaka A, Brunstein MC, Bozec A, Fischel JL, Milano G, Van Obberghen-Schilling E.

Acta Oncol. 2008;47(8):1502-12. doi: 10.1080/02841860802089801.


Caveolin-1 overexpression is associated with simultaneous abnormal expression of the E-cadherin/α-β catenins complex and multiple ErbB receptors and with lymph nodes metastasis in head and neck squamous cell carcinomas.

Masuelli L, Budillon A, Marzocchella L, Mrozek MA, Vitolo D, Di Gennaro E, Losito S, Sale P, Longo F, Ionna F, Lista F, Muraro R, Modesti A, Bei R.

J Cell Physiol. 2012 Sep;227(9):3344-53. doi: 10.1002/jcp.24034.


EGFR antisense treatment of human HNSCC cell lines down-regulates VEGF expression and endothelial cell migration.

Riedel F, Götte K, Li M, Hörmann K, Grandis JR.

Int J Oncol. 2002 Jul;21(1):11-6.


Cross-talk between estrogen receptor and epidermal growth factor receptor in head and neck squamous cell carcinoma.

Egloff AM, Rothstein ME, Seethala R, Siegfried JM, Grandis JR, Stabile LP.

Clin Cancer Res. 2009 Nov 1;15(21):6529-40. doi: 10.1158/1078-0432.CCR-09-0862. Epub 2009 Oct 13.


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