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Items: 1 to 20 of 383

1.

Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.

Gao SM, Chen CQ, Wang LY, Hong LL, Wu JB, Dong PH, Yu FJ.

Exp Hematol. 2013 Mar;41(3):261-70.e4. doi: 10.1016/j.exphem.2012.10.012. Epub 2012 Oct 27.

PMID:
23111066
2.

Pure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class I histone deacetylases.

Chen CQ, Yu K, Yan QX, Xing CY, Chen Y, Yan Z, Shi YF, Zhao KW, Gao SM.

Carcinogenesis. 2013 Jul;34(7):1442-9. doi: 10.1093/carcin/bgt070. Epub 2013 Feb 21.

PMID:
23430957
3.

Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells.

Xiong H, Du W, Zhang YJ, Hong J, Su WY, Tang JT, Wang YC, Lu R, Fang JY.

Mol Carcinog. 2012 Feb;51(2):174-84. doi: 10.1002/mc.20777. Epub 2011 Apr 22.

PMID:
21520296
4.

Epigenetic deregulated miR-375 contributes to the constitutive activation of JAK2/STAT signaling in myeloproliferative neoplasm.

Yin LH, Zheng XQ, Li HY, Bi LX, Shi YF, Ye AF, Wu JB, Gao SM.

Leuk Res. 2015 Apr;39(4):471-8. doi: 10.1016/j.leukres.2015.01.009. Epub 2015 Jan 28.

PMID:
25666256
5.

JAK2 V617F-dependent upregulation of PU.1 expression in the peripheral blood of myeloproliferative neoplasm patients.

Irino T, Uemura M, Yamane H, Umemura S, Utsumi T, Kakazu N, Shirakawa T, Ito M, Suzuki T, Kinoshita K.

PLoS One. 2011;6(7):e22148. doi: 10.1371/journal.pone.0022148. Epub 2011 Jul 18.

6.

Epigenetic inactivation of suppressors of cytokine signalling in Philadelphia-negative chronic myeloproliferative disorders.

Capello D, Deambrogi C, Rossi D, Lischetti T, Piranda D, Cerri M, Spina V, Rasi S, Gaidano G, Lunghi M.

Br J Haematol. 2008 May;141(4):504-11. doi: 10.1111/j.1365-2141.2008.07072.x. Epub 2008 Mar 3.

PMID:
18318760
7.

Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders.

Fourouclas N, Li J, Gilby DC, Campbell PJ, Beer PA, Boyd EM, Goodeve AC, Bareford D, Harrison CN, Reilly JT, Green AR, Bench AJ.

Haematologica. 2008 Nov;93(11):1635-44. doi: 10.3324/haematol.13043. Epub 2008 Sep 24.

8.

Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling.

van de Geijn GJ, Gits J, Touw IP.

J Leukoc Biol. 2004 Jul;76(1):237-44. Epub 2004 Apr 23.

PMID:
15107455
9.

Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-γ-induced vascular smooth muscle cells.

Xiang S, Dong NG, Liu JP, Wang Y, Shi JW, Wei ZJ, Hu XJ, Gong L.

J Huazhong Univ Sci Technolog Med Sci. 2013 Oct;33(5):615-22. doi: 10.1007/s11596-013-1168-x. Epub 2013 Oct 20.

PMID:
24142708
10.
11.

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3.

Hookham MB, Elliott J, Suessmuth Y, Staerk J, Ward AC, Vainchenker W, Percy MJ, McMullin MF, Constantinescu SN, Johnston JA.

Blood. 2007 Jun 1;109(11):4924-9. Epub 2007 Feb 22.

12.

Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.

Norkina O, Dolganiuc A, Catalano D, Kodys K, Mandrekar P, Syed A, Efros M, Szabo G.

Alcohol Clin Exp Res. 2008 Sep;32(9):1565-73. doi: 10.1111/j.1530-0277.2008.00726.x. Epub 2008 Jul 9.

13.

Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer.

Chen CQ, Chen CS, Chen JJ, Zhou LP, Xu HL, Jin WW, Wu JB, Gao SM.

Mol Cell Biochem. 2013 Nov;383(1-2):137-48. doi: 10.1007/s11010-013-1762-z. Epub 2013 Jul 19.

PMID:
23867991
14.

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

Slattery ML, Lundgreen A, Kadlubar SA, Bondurant KL, Wolff RK.

Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841. Epub 2011 Nov 28.

15.

Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans.

Okinaga T, Ariyoshi W, Akifusa S, Nishihara T.

Med Microbiol Immunol. 2013 Apr;202(2):167-74. doi: 10.1007/s00430-012-0282-x. Epub 2012 Dec 25.

PMID:
23266654
16.

Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis.

Ortiz-Muñoz G, Martin-Ventura JL, Hernandez-Vargas P, Mallavia B, Lopez-Parra V, Lopez-Franco O, Muñoz-Garcia B, Fernandez-Vizarra P, Ortega L, Egido J, Gomez-Guerrero C.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):525-31. doi: 10.1161/ATVBAHA.108.173781. Epub 2009 Jan 22.

17.

Lycorine induces cell death in MM by suppressing Janus Kinase/signal transducer and activator of transcription via inducing the expression of SOCS1.

Jin Z, Zhou S, Zhang Y, Ye H, Jiang S, Yu K, Ma Y.

Biomed Pharmacother. 2016 Dec;84:1645-1653. doi: 10.1016/j.biopha.2016.10.069. Epub 2016 Nov 12.

PMID:
27847203
18.

Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT3/SOCS3 signaling pathway in MHCC97H cells.

Ji Y, Wang Z, Li Z, Li K, Le X, Zhang T.

Cell Physiol Biochem. 2012;29(5-6):863-74. doi: 10.1159/000171034. Epub 2012 May 11.

19.

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