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Items: 1 to 20 of 90

1.

Characterization of rat liver proteins adducted by reactive metabolites of menthofuran.

Khojasteh SC, Hartley DP, Ford KA, Uppal H, Oishi S, Nelson SD.

Chem Res Toxicol. 2012 Nov 19;25(11):2301-9. doi: 10.1021/tx300144d. Epub 2012 Nov 6.

PMID:
23106769
2.

Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.

Khojasteh-Bakht SC, Chen W, Koenigs LL, Peter RM, Nelson SD.

Drug Metab Dispos. 1999 May;27(5):574-80.

3.

Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione.

Thomassen D, Slattery JT, Nelson SD.

J Pharmacol Exp Ther. 1990 May;253(2):567-72.

PMID:
2338648
4.

Metabolism and toxicity of menthofuran in rat liver slices and in rats.

Khojasteh SC, Oishi S, Nelson SD.

Chem Res Toxicol. 2010 Nov 15;23(11):1824-32. doi: 10.1021/tx100268g. Epub 2010 Oct 14.

5.

Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone.

Nelson SD, McClanahan RH, Thomassen D, Gordon WP, Knebel N.

Xenobiotica. 1992 Sep-Oct;22(9-10):1157-64. Review.

PMID:
1441606
6.

Reactive intermediates in the oxidation of menthofuran by cytochromes P-450.

Thomassen D, Knebel N, Slattery JT, McClanahan RH, Nelson SD.

Chem Res Toxicol. 1992 Jan-Feb;5(1):123-30.

PMID:
1581528
7.

Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2003 Oct;31(10):1208-13.

8.

Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria.

Guo J, Prokai-Tatrai K, Nguyen V, Rauniyar N, Ughy B, Prokai L.

J Proteomics. 2011 Oct 19;74(11):2370-9. doi: 10.1016/j.jprot.2011.07.009. Epub 2011 Jul 23.

9.

14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats.

Ferguson LJ, Lebetkin EH, Lih FB, Tomer KB, Parkinson HD, Borghoff SJ, Burka LT.

J Toxicol Environ Health A. 2007 Sep;70(17):1416-23.

PMID:
17687727
10.

Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation.

Moon KH, Lee YM, Song BJ.

Free Radic Biol Med. 2010 Feb 1;48(3):391-8. doi: 10.1016/j.freeradbiomed.2009.11.008. Epub 2009 Nov 14.

11.

Proteomic alteration of mitochondrial aldehyde dehydrogenase 2 in sepsis regulated by heat shock response.

Chen HW, Kuo HT, Hwang LC, Kuo MF, Yang RC.

Shock. 2007 Dec;28(6):710-6.

PMID:
17607160
12.

SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity.

Lu Z, Bourdi M, Li JH, Aponte AM, Chen Y, Lombard DB, Gucek M, Pohl LR, Sack MN.

EMBO Rep. 2011 Jul 1;12(8):840-6. doi: 10.1038/embor.2011.121.

13.

Liver protein targets of hepatotoxic 4-bromophenol metabolites.

Koen YM, Hajovsky H, Liu K, Williams TD, Galeva NA, Staudinger JL, Hanzlik RP.

Chem Res Toxicol. 2012 Aug 20;25(8):1777-86. doi: 10.1021/tx3002675. Epub 2012 Aug 3.

14.

The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.

Gordon WP, Huitric AC, Seth CL, McClanahan RH, Nelson SD.

Drug Metab Dispos. 1987 Sep-Oct;15(5):589-94.

PMID:
2891472
15.

A decades-long investigation of acute metabolism-based hepatotoxicity by herbal constituents: a case study of pennyroyal oil.

Gordon P, Khojasteh SC.

Drug Metab Rev. 2015 Feb;47(1):12-20. doi: 10.3109/03602532.2014.990032. Epub 2014 Dec 16. Review.

PMID:
25512112
16.

Oxidation of 4-hydroxy-2-nonenal by succinic semialdehyde dehydrogenase (ALDH5A).

Murphy TC, Amarnath V, Gibson KM, Picklo MJ Sr.

J Neurochem. 2003 Jul;86(2):298-305.

17.

Malondialdehyde inhibits an AMPK-mediated nuclear translocation and repression activity of ALDH2 in transcription.

Choi JW, Kim JH, Cho SC, Ha MK, Song KY, Youn HD, Park SC.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):400-6. doi: 10.1016/j.bbrc.2010.11.131. Epub 2010 Dec 3.

PMID:
21130747
18.

Inhibition of aldehyde dehydrogenase 2 activity enhances antimycin-induced rat cardiomyocytes apoptosis through activation of MAPK signaling pathway.

Zhang P, Xu D, Wang S, Fu H, Wang K, Zou Y, Sun A, Ge J.

Biomed Pharmacother. 2011 Dec;65(8):590-3. doi: 10.1016/j.biopha.2009.12.001. Epub 2009 Dec 30.

PMID:
21123025
19.

Steady-state metabolism of ethanol in perfused rat livers treated with cyanamide: quantitative analysis of acetaldehyde effects on the metabolic flux rates.

Yao CT, Lai CL, Yin SJ.

Alcohol Clin Exp Res. 2015 May;39(5):798-807. doi: 10.1111/acer.12701. Epub 2015 Apr 1.

PMID:
25827479
20.

Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase.

Mahmoud SS, Croteau RB.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14481-6. Epub 2003 Nov 17.

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